Atherosclerotic Plaque Regression: Fact or Fiction? | springermedizin.de

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Cardiovascular Drugs and Therapy

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01.08.2010

Atherosclerotic Plaque Regression: Fact or Fiction?

verfasst von: Nesan Shanmugam, Ana Román-Rego, Peter Ong, Juan Carlos Kaski

Erschienen in: Cardiovascular Drugs and Therapy | Ausgabe 4/2010

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Abstract

Coronary artery disease is the major cause of death in the western world. The formation and rapid progression of atheromatous plaques can lead to serious cardiovascular events in patients with atherosclerosis. The better understanding, in recent years, of the mechanisms leading to atheromatous plaque growth and disruption and the availability of powerful HMG CoA-reductase inhibitors (statins) has permitted the consideration of plaque regression as a realistic therapeutic goal. This article reviews the existing evidence underpinning current therapeutic strategies aimed at achieving atherosclerotic plaque regression. In this review we also discuss imaging modalities for the assessment of plaque regression, predictors of regression and whether plaque regression is associated with a survival benefit.

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Titel: Atherosclerotic Plaque Regression: Fact or Fiction?
verfasst von: Nesan Shanmugam
Ana Román-Rego
Peter Ong
Juan Carlos Kaski
Publikationsdatum: 01.08.2010
Verlag: Springer US
Erschienen in: Cardiovascular Drugs and Therapy / Ausgabe 4/2010
Print ISSN: 0920-3206
Elektronische ISSN: 1573-7241
DOI: https://doi.org/10.1007/s10557-010-6241-0

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