Erschienen in:
23.10.2018 | Editorial
Benefits and risks of the P/F approach
verfasst von:
L. Gattinoni, F. Vassalli, F. Romitti
Erschienen in:
Intensive Care Medicine
|
Ausgabe 12/2018
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Excerpt
The PaO
2/FIO
2 ratio represents the pressure exerted in the blood by the unbound molecules of oxygen, normalized to the fractional volume of inspired oxygen. The PaO
2/FIO
2 ratio is used to assess the lung’s capability to oxygenate the blood, primarily in ARDS, where its thresholds of 150, 200, and 300 are used/proposed to classify ARDS severity [
1,
2]. Ideally, a given PaO
2/FIO
2 ratio value should correspond to a definite lung severity, independently of FIO
2. In reality, the same severity may be associated with quite different PaO
2/FIO
2 values, depending on several factors, as previously described [
3]. …