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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 9/2016

01.09.2016 | Occupational Allergies (JA Poole, Section Editor)

Biomarkers in Occupational Asthma

verfasst von: Javier Dominguez-Ortega, Pilar Barranco, Rosa Rodríguez-Pérez, Santiago Quirce

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 9/2016

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Abstract

Purpose of Review

Work-related asthma is a common disorder among adult asthma patients, and in the case of occupational asthma, it is induced by workplace exposures.

Recent Findings

Occupational asthma provides an excellent model and benchmark for identifying and testing different allergy or inflammatory biomarkers associated with its inception or progression. Moreover, specific inhalation challenge with the incriminated agent represents an experimental setting to identify and validate potential systemic or local biomarkers. Some biomarkers are mainly blood-borne, while local airway biomarkers are derived from inflammatory or resident cells. Genetic and gene–environment interaction studies also provide an excellent framework to identify relevant profiles associated with the risk of developing these work-related conditions.

Summary

Despite significant efforts to identify clinically relevant inflammatory and genomic markers for occupational asthma, apart from the documented utility of airway inflammatory biomarkers, it remains elusive to define specific markers or signatures clearly associated with different endpoints or outcomes in occupational asthma.
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Metadaten
Titel
Biomarkers in Occupational Asthma
verfasst von
Javier Dominguez-Ortega
Pilar Barranco
Rosa Rodríguez-Pérez
Santiago Quirce
Publikationsdatum
01.09.2016
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 9/2016
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-016-0644-3

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16.04.2024 Tonsillektomie Nachrichten

Gegenüber der vollständigen Entfernung der Gaumenmandeln hat die intrakapsuläre Tonsillektomie einige Vorteile, wie HNO-Fachleute aus den USA hervorheben. Sie haben die aktuelle Literatur zu dem Verfahren gesichtet.

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