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Current Allergy and Asthma Reports

Erschienen in:

01.09.2016 | Allergens (RK Bush and JA Woodfolk, Section Editors)

Proteomics for Allergy: from Proteins to the Patients

verfasst von: Emmanuel Nony, Maxime Le Mignon, Sébastien Brier, Armelle Martelet, Philippe Moingeon

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 9/2016

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Abstract

Proteomics encompasses a variety of approaches unraveling both the structural features, post-translational modifications, and abundance of proteins. As of today, proteomic studies have shed light on the primary structure of about 850 allergens, enabling the design of microarrays for improved molecular diagnosis. Proteomic methods including mass spectrometry allow as well to investigate protein-protein interactions, thus yielding precise information on critical epitopes on the surface of allergens. Mass spectrometry is now being applied to the unambiguous identification, characterization, and comprehensive quantification of allergens in a variety of matrices, as diverse as food samples and allergen immunotherapy drug products. As such, it represents a method of choice for quality testing of allergen immunotherapy products.

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Titel: Proteomics for Allergy: from Proteins to the Patients
verfasst von: Emmanuel Nony
Maxime Le Mignon
Sébastien Brier
Armelle Martelet
Philippe Moingeon
Publikationsdatum: 01.09.2016
Verlag: Springer US
Erschienen in: Current Allergy and Asthma Reports / Ausgabe 9/2016
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI: https://doi.org/10.1007/s11882-016-0642-5

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Springer Medizin

Proteomics for Allergy: from Proteins to the Patients

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Intrakapsuläre Tonsillektomie gewinnt an Boden

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