Erschienen in:
12.03.2019 | Breast Oncology
Borderline and Malignant Phyllodes Tumors: How Often do They Locally Recur and is There Anything we can do About it?
verfasst von:
Richard J. Barth Jr., MD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 7/2019
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Excerpt
For the past 10 years, I have received an automatic monthly email from my librarian with new papers published on phyllodes tumors (PTs). Although these are unusual neoplasms, investigators like to study them; I commonly have a couple of abstracts to read each month. Except for one prospective study, the literature on PTs consists of retrospective studies of clinical outcomes or clinical-pathologic associations. Just about everyone agrees about certain aspects of surgical treatment: (1) the local recurrence (LR) rate is much lower when negative margins are achieved; (2) borderline and malignant PTs locally recur with equal frequencies; and (3) distant metastases occur in 10–20% of patients after resection of malignant PTs, and rarely after borderline phyllodes resections. In the current issue of
Annals of Surgical Oncology, Dr. Spanheimer and associates elegantly describe the clinical outcomes of a large cohort of borderline and malignant phyllodes patients (124 patients over a 60-year period) and provide data that confirms concepts 1–3.
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