Background
Methods
Patients
Anesthesia
Data collection and outcomes
Statistical analysis
Results
Patients’ characteristics
General anesthesia (n = 188) | Spinal anesthesia (n = 1,728) | P value | |
---|---|---|---|
Age | 74.2 ± 5.8 | 73.4 ± 6.3 | 0.06 |
Gender, n (%) | 0.17 | ||
Male | 121 (64.4%) | 1,199 (69.4%) | |
Female | 67 (35.6%) | 529 (30.6%) | |
BMI | 24.10 ± 3.35 | 24.43 ± 3.92 | 0.32 |
ASA grade ≥ III, n (%) | 119 (63.3%) | 1,074 (62.2%) | 0.79 |
Surgery site, n (%) | 0.37 | ||
Hip | 84 (44.7%) | 699 (40.5%) | |
Knee | 85 (45.2%) | 803 (46.5%) | |
Others | 19 (10.1%) | 226 (13.1%) | |
Comorbidities, n (%) | |||
Hypertension | 82 (43.6%) | 806 (46.6%) | 0.43 |
Diabetes | 28 (14.9%) | 256 (14.8%) | 0.98 |
Respiratory disease | 16 (8.5%) | 111 (6.4%) | 0.28 |
Cardiovascular disease | 21 (11.2%) | 256 (14.8%) | 0.64 |
Stroke | 11 (5.9%) | 138 (8.0%) | 0.30 |
Smoking, n (%) | 20 (10.6%) | 177 (10.2%) | 0.87 |
Drinking, n (%) | 5 (2.7%) | 54 (3.1%) | 0.70 |
Laboratory tests | |||
WBC | 8.0 ± 3.2 | 7.6 ± 2.6 | 0.42 |
BPC | 217.9 ± 72.3 | 217.5 ± 71.4 | 0.94 |
Hb | 117.1 ± 19.6 | 115.2 ± 17.0 | 0.53 |
Scr | 66.0 ± 26.2 | 66.0 ± 33.7 | 0.99 |
SA | 37.1 ± 4.9 | 37.7 ± 4.3 | 0.15 |
INR | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.12 |
Operation time > 1.5 h, n (%) | 160 (85.0%) | 1,231 (71.2%) | < 0.01 |
Intraoperative hemodynamic changes
ICU admission, mortality, and postoperative complications
General anesthesia | Spinal anesthesia | P value | |
---|---|---|---|
ICU admission, n (%) | 44 (23.8%) | 110 (6.4%) | < 0.01 |
Mortality, n (%) | 1 (0.5%) | 3 (0.2%) | 0.86 |
Complications | |||
Pulmonary infection, n (%) | 1 (0.5%) | 8 (0.5%) | 1.00 |
Pulmonary embolism, n (%) | 1 (0.5%) | 4 (0.2%) | 0.99 |
Deep vein thrombosis, n (%) | 5 (2.7%) | 26 (1.5%) | 0.36 |
Unplanned intubation, n (%) | 7 (3.8%) | 2 (0.1%) | < 0.01 |
Blood transfusion, n (%) | 13 (7.0%) | 90 (5.2%) | 0.32 |
Reoperation, n (%) | 2 (1.1%) | 19 (1.1%) | 1.00 |
Urinary retention, n (%) | 2 (1.1%) | 30 (1.7%) | 0.70 |
Odds ratio | 95% CI | P value | |
---|---|---|---|
Spinal vs. General anesthesia | 0.240 | 0.115–0.498 | < 0.01 |
Age ≥ 80 years vs. < 80 years | 7.219 | 3.814–13.664 | < 0.01 |
Operation time ≥ 1.5 h vs. < 1.5 h | 8.346 | 4.283–16.264 | < 0.01 |
Preoperative diabetes | 3.027 | 1.420–6.451 | < 0.01 |