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Erschienen in: Archives of Gynecology and Obstetrics 1/2022

12.05.2021 | Maternal-Fetal Medicine

Can sonographic changes in cervical length during pregnancy predict the need for cervical ripening in term pregnancies?

verfasst von: Hanoch Schreiber, Michal Ovadia, Hadar Gluska, Maya Sharon-Weiner, Tal Biron-Shental, Ofer Markovitch

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 1/2022

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Abstract

Purpose

To evaluate the effect of changes in sonographic cervical length (CL) measured at 14–16 and 21–24 weeks of gestation, on cervical ripening in term pregnancies.

Methods

This retrospective, cohort study included term pregnancies with CL measured with transvaginal sonography (CL1 at 14–16 weeks gestation and CL2 at 21–24 weeks). History of preterm labor, multiple gestations, planned caesarean section, fetal anomalies and stillbirths were excluded. Participants were grouped based on ≥ 10% vs. < 10% CL shortening between measurements. The primary outcome was whether cervical shortening < 10% between CL1 and CL2 was associated with increased use of cervical ripening. Secondary outcomes were gestational age at delivery, delivery mode and birthweight.

Results

Among 267 women who met the inclusion criteria, CL decreased ≥ 10% between scans in 70 (26.3%) and < 10% in 197 (73.7%). Baseline characteristics were similar between groups. Fewer women with ≥ 10% shortening between scans, underwent cervical ripening (7.1% vs. 16.8%, p < 0.05). In addition, in the ≥ 10% group, although CL2 was in the normal range, it was shorter than in the < 10% group (34.3 ± 6.7 mm vs. 40.1 ± 6.4 mm, p < 0.01).

Conclusion

Decrease in cervical length > 10% between 14–16 and 21–24-weeks’ gestation is associated with lower use of cervical ripening at term.
Literatur
1.
Zurück zum Zitat Garfield RE, Saade G, Buhimschi C, Buhimschi I, Shi L, Shi SQ, Chwalisz K (1998) Control and assessment of the uterus and cervix during pregnancy and labour. Hum Reprod Update 4(5):673–695CrossRef Garfield RE, Saade G, Buhimschi C, Buhimschi I, Shi L, Shi SQ, Chwalisz K (1998) Control and assessment of the uterus and cervix during pregnancy and labour. Hum Reprod Update 4(5):673–695CrossRef
2.
Zurück zum Zitat Hassan SS, Romero R, Berry SM, Dang K, Blackwell SC, Treadwell MC, Wolfe HM (2000) Patients with an ultrasonographic cervical length≤ 15 mm have nearly a 50% risk of early spontaneous preterm delivery. Am J Obstet Gynecol 182:1458–1467CrossRef Hassan SS, Romero R, Berry SM, Dang K, Blackwell SC, Treadwell MC, Wolfe HM (2000) Patients with an ultrasonographic cervical length≤ 15 mm have nearly a 50% risk of early spontaneous preterm delivery. Am J Obstet Gynecol 182:1458–1467CrossRef
3.
Zurück zum Zitat Berghella V, Bega G, Tolosa JE, Berghella M (2003) Ultrasound assessment of the cervix. Clin Obstet Gynecol 46:947–962CrossRef Berghella V, Bega G, Tolosa JE, Berghella M (2003) Ultrasound assessment of the cervix. Clin Obstet Gynecol 46:947–962CrossRef
4.
Zurück zum Zitat Goldenberg RL, Culhane JF, Iams JD, Romero R (2008) Epidemiology and causes of preterm birth. Lancet 371(9606):75–84CrossRef Goldenberg RL, Culhane JF, Iams JD, Romero R (2008) Epidemiology and causes of preterm birth. Lancet 371(9606):75–84CrossRef
5.
Zurück zum Zitat Hibbard JU, Tart M, Moawad AH (2000) Cervical length at 16–22 weeks’ gestation and risk for preterm delivery. Obstet Gynecol 96(6):972–978PubMed Hibbard JU, Tart M, Moawad AH (2000) Cervical length at 16–22 weeks’ gestation and risk for preterm delivery. Obstet Gynecol 96(6):972–978PubMed
6.
Zurück zum Zitat Baños N, Murillo-Bravo C, Julià C, Migliorelli F, Perez-Moreno A, Ríos J et al (2018) Mid-trimester sonographic cervical consistency index to predict spontaneous preterm birth in a low-risk population. Ultrasound Obstet Gynecol 51:629–636CrossRef Baños N, Murillo-Bravo C, Julià C, Migliorelli F, Perez-Moreno A, Ríos J et al (2018) Mid-trimester sonographic cervical consistency index to predict spontaneous preterm birth in a low-risk population. Ultrasound Obstet Gynecol 51:629–636CrossRef
7.
Zurück zum Zitat Odibo AO, Berghella V, Reddy U, Tolosa JE, Wapner RJ (2001) Does transvaginal ultrasound of the cervix predict preterm premature rupture of membranes in a high-risk population? Ultrasound Obstet Gynecol 18(3):223–227CrossRef Odibo AO, Berghella V, Reddy U, Tolosa JE, Wapner RJ (2001) Does transvaginal ultrasound of the cervix predict preterm premature rupture of membranes in a high-risk population? Ultrasound Obstet Gynecol 18(3):223–227CrossRef
8.
Zurück zum Zitat Heath VCF, Southall TR, Souka AP, Novakov A, Nicolaides KH (1998) Cervical length at 23 weeks of gestation: relation to demographic characteristics and previous obstetric history. Ultrasound Obstet Gynecol 12(5):304–311CrossRef Heath VCF, Southall TR, Souka AP, Novakov A, Nicolaides KH (1998) Cervical length at 23 weeks of gestation: relation to demographic characteristics and previous obstetric history. Ultrasound Obstet Gynecol 12(5):304–311CrossRef
9.
Zurück zum Zitat Burger M, Weber-Rössler T, Willmann M (1997) Measurement of the pregnant cervix by transvaginal sonography: an interobserver study and new standards to improve the interobserver variability. Ultrasound Obstet Gynecol 9(3):188–193CrossRef Burger M, Weber-Rössler T, Willmann M (1997) Measurement of the pregnant cervix by transvaginal sonography: an interobserver study and new standards to improve the interobserver variability. Ultrasound Obstet Gynecol 9(3):188–193CrossRef
10.
Zurück zum Zitat Ozdemir I, Demirci F, Yucel O, Erkorkmaz U (2007) Ultrasonographic cervical length measurement at 10–14 and 20–24 weeks gestation and the risk of preterm delivery. Eur J Obstet Gynecol Reproduc Biol 130(2):176–179CrossRef Ozdemir I, Demirci F, Yucel O, Erkorkmaz U (2007) Ultrasonographic cervical length measurement at 10–14 and 20–24 weeks gestation and the risk of preterm delivery. Eur J Obstet Gynecol Reproduc Biol 130(2):176–179CrossRef
11.
Zurück zum Zitat Souka AP, Papastefanou I, Michalitsi V, Salambasis K, Chrelias C, Salamalekis G, Kassanos D (2011) Cervical length changes from the first to second trimester of pregnancy, and prediction of preterm birth by first-trimester sonographic cervical measurement. J Ultrasound Med 30(7):997–1002CrossRef Souka AP, Papastefanou I, Michalitsi V, Salambasis K, Chrelias C, Salamalekis G, Kassanos D (2011) Cervical length changes from the first to second trimester of pregnancy, and prediction of preterm birth by first-trimester sonographic cervical measurement. J Ultrasound Med 30(7):997–1002CrossRef
12.
Zurück zum Zitat Greco E, Gupta R, Syngelaki A, Poon LC, Nicolaides KH (2012) First-trimester screening for spontaneous preterm delivery with maternal characteristics and cervical length. Fetal Diag Ther 31(3):154–161CrossRef Greco E, Gupta R, Syngelaki A, Poon LC, Nicolaides KH (2012) First-trimester screening for spontaneous preterm delivery with maternal characteristics and cervical length. Fetal Diag Ther 31(3):154–161CrossRef
13.
Zurück zum Zitat Miller ES, Einerson B, Sahabi S, Grobman WA (2014) Association between second-trimester cervical length and cesarean delivery in multiparas. J Ultrasound Med 33:1733–1736CrossRef Miller ES, Einerson B, Sahabi S, Grobman WA (2014) Association between second-trimester cervical length and cesarean delivery in multiparas. J Ultrasound Med 33:1733–1736CrossRef
14.
Zurück zum Zitat Smith GC, Celik E, To M, Khouri O, Nicolaides KH (2008) Cervical length at mid-pregnancy and the risk of primary cesarean delivery. New Engl J Medicine 358:1346–1353CrossRef Smith GC, Celik E, To M, Khouri O, Nicolaides KH (2008) Cervical length at mid-pregnancy and the risk of primary cesarean delivery. New Engl J Medicine 358:1346–1353CrossRef
15.
Zurück zum Zitat Miller ES, Sakowicz A, Donelan EA, Grobman WA (2015) Does midtrimester cervical length aid in predicting vaginal birth after cesarean? Am J Obstet Gynecol 212:791-e1CrossRef Miller ES, Sakowicz A, Donelan EA, Grobman WA (2015) Does midtrimester cervical length aid in predicting vaginal birth after cesarean? Am J Obstet Gynecol 212:791-e1CrossRef
16.
Zurück zum Zitat Heath VCF, Souka AP, Erasmus I, Gibb DMF, Nicolaides KH (1998) Cervical length at 23 weeks of gestation: the value of Shirodkar suture for the short cervix. Ultrasound Obstet Gynecol 12:318–322CrossRef Heath VCF, Souka AP, Erasmus I, Gibb DMF, Nicolaides KH (1998) Cervical length at 23 weeks of gestation: the value of Shirodkar suture for the short cervix. Ultrasound Obstet Gynecol 12:318–322CrossRef
17.
Zurück zum Zitat Berghella V, Roman A, Daskalakis C, Ness A, Baxter JK (2007) Gestational age at cervical length measurement and incidence of preterm birth. Obstet Gynecol 110:311–317CrossRef Berghella V, Roman A, Daskalakis C, Ness A, Baxter JK (2007) Gestational age at cervical length measurement and incidence of preterm birth. Obstet Gynecol 110:311–317CrossRef
18.
Zurück zum Zitat Shynlova O, Oldenhof A, Dorogin A, Xu Q, Mu J, Nashman N, Lye SJ (2006) Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midgestation. Biol Reprod 74:839–849CrossRef Shynlova O, Oldenhof A, Dorogin A, Xu Q, Mu J, Nashman N, Lye SJ (2006) Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midgestation. Biol Reprod 74:839–849CrossRef
Metadaten
Titel
Can sonographic changes in cervical length during pregnancy predict the need for cervical ripening in term pregnancies?
verfasst von
Hanoch Schreiber
Michal Ovadia
Hadar Gluska
Maya Sharon-Weiner
Tal Biron-Shental
Ofer Markovitch
Publikationsdatum
12.05.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 1/2022
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-021-06089-5

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