Ausgabe 1/2022
Inhalt (19 Artikel)
Intratumoral Foxp3+RORγt+ T cell infiltration determines poor prognosis and immunoevasive contexture in gastric cancer patients
Yuchao Fei, Yifan Cao, Yun Gu, Hanji Fang, Yifan Chen, Jieti Wang, Xin Liu, Kunpeng Lv, Xudong He, Chao Lin, Hao Liu, He Li, Hongyong He, Ruochen Li, Heng Zhang, Weijuan Zhang
Reduced frequency of cytotoxic CD56dim CD16+ NK cells leads to impaired antibody-dependent degranulation in EBV-positive classical Hodgkin lymphoma
Elena Pánisová, Anna Lünemann, Simone Bürgler, Monika Kotur, Julien Lazarovici, Alina Danu, Meike Kaulfuss, Juliane Mietz, Obinna Chijioke, Christian Münz, Pierre Busson, Christoph Berger, David Ghez, Tarik Azzi
Imaging features of gadoxetic acid-enhanced MR imaging for evaluation of tumor-infiltrating CD8 cells and PD-L1 expression in hepatocellular carcinoma
Lin Sun, Luwen Mu, Jing Zhou, Wenjie Tang, Linqi Zhang, Sidong Xie, Jingbiao Chen, Jin Wang
Lenalidomide enhances the efficacy of anti-BCMA CAR-T treatment in relapsed/refractory multiple myeloma: a case report and revies of the literature
Guoxing Zhao, Runhong Wei, Lei Feng, Yi Wu, Feng He, Mingxing Xiao, Zhi Cheng
Predictive value of NLR, TILs (CD4+/CD8+) and PD-L1 expression for prognosis and response to preoperative chemotherapy in gastric cancer
Ina Valeria Zurlo, Mattia Schino, Antonia Strippoli, Maria Alessandra Calegari, Alessandra Cocomazzi, Alessandra Cassano, Carmelo Pozzo, Mariantonietta Di Salvatore, Riccardo Ricci, Carlo Barone, Emilio Bria, Giampaolo Tortora, Luigi Maria Larocca, Michele Basso, Maurizio Martini
CD74+ macrophages are associated with favorable prognosis and immune contexture in hepatocellular carcinoma
Nan Xiao, Kangshuai Li, Xiaodong Zhu, Bin Xu, Xuefeng Liu, Ming Lei, Hui-Chuan Sun
SIRPα-specific monoclonal antibody enables antibody-dependent phagocytosis of neuroblastoma cells
Meriem Bahri, Sareetha Kailayangiri, Sarah Vermeulen, Natacha Galopin, Claudia Rossig, François Paris, Sophie Fougeray, Stéphane Birklé
Impact of preoperative plasma levels of interleukin 6 and interleukin 6 soluble receptor on disease outcomes after radical cystectomy for bladder cancer
Victor M. Schuettfort, Benjamin Pradere, Quoc-Dien Trinh, David D’Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Reza Sari Motlagh, Michael Rink, Pierre I. Karakiewicz, Piotr Chlosta, Jeremy Yuen-Chun Teoh, Yair Lotan, Douglas Scherr, Mohammad Abufaraj, Marco Moschini, Shahrokh F. Shariat
Conditioning treatment with CD27 Ab enhances expansion and antitumor activity of adoptively transferred T cells in mice
Anna Wasiuk, Jeff Weidlick, Crystal Sisson, Jenifer Widger, Andrea Crocker, Laura Vitale, Henry C. Marsh, Tibor Keler, Li-Zhen He
PTCH1 mutation promotes antitumor immunity and the response to immune checkpoint inhibitors in colorectal cancer patients
Yanni Wang, Huan Chen, Xi Jiao, Lihong Wu, Ying Yang, Jiao Zhang, Lijia Wu, Chang Liu, Na Zhuo, Shuang Li, Jifang Gong, Jian Li, Xiaotian Zhang, Xicheng Wang, Zhi Peng, Changsong Qi, Zhenghang Wang, Jie Li, Yan Li, Zhihao Lu, Henghui Zhang, Lin Shen
Construction of TME and Identification of crosstalk between malignant cells and macrophages by SPP1 in hepatocellular carcinoma
Lulu Liu, Ruyi Zhang, Jingwen Deng, Xiaomeng Dai, Xudong Zhu, Qihan Fu, Hangyu Zhang, Zhou Tong, Peng Zhao, Weijia Fang, Yi Zheng, Xuanwen Bao
CD40 and CD80/86 signaling in cDC1s mediate effective neoantigen vaccination and generation of antigen-specific CX3CR1+ CD8+ T cells
Takayoshi Yamauchi, Toshifumi Hoki, Takaaki Oba, Ryutaro Kajihara, Kristopher Attwood, Xuefang Cao, Fumito Ito
Anti-disialoganglioside antibody internalization by neuroblastoma cells as a mechanism of immunotherapy resistance
Rachelle Tibbetts, Kee Kiat Yeo, Sakunthala Muthugounder, Meng-Hua Lee, Cham Jung, Tania Porras-Corredor, Michael A. Sheard, Shahab Asgharzadeh
Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30
Savannah E. Butler, Rachel A. Brog, Cheryl H. Chang, Charles L. Sentman, Yina H. Huang, Margaret E. Ackerman
STAT3 is over-activated within CD163pos bone marrow macrophages in both Multiple Myeloma and the benign pre-condition MGUS
Morten N. Andersen, Niels F. Andersen, Kristina L. Lauridsen, Anders Etzerodt, Boe S. Sorensen, Niels Abildgaard, Trine Plesner, Marianne Hokland, Holger J. Møller
Maintenance of WT1 expression in tumor cells is associated with a good prognosis in malignant glioma patients treated with WT1 peptide vaccine immunotherapy
Chisato Yokota, Naoki Kagawa, Koji Takano, Yasuyoshi Chiba, Manabu Kinoshita, Noriyuki Kijima, Yusuke Oji, Yoshihiro Oka, Haruo Sugiyama, Akihiro Tsuboi, Shuichi Izumoto, Haruhiko Kishima, Naoya Hashimoto
Increased serum cholesterol and long-chain fatty acid levels are associated with the efficacy of nivolumab in patients with non-small cell lung cancer
Masato Karayama, Naoki Inui, Yusuke Inoue, Katsuhiro Yoshimura, Kazutaka Mori, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Kazuhiro Asada, Tomohiro Uto, Masato Fujii, Takashi Matsui, Shun Matsuura, Dai Hashimoto, Mikio Toyoshima, Hideki Kusagaya, Hiroyuki Matsuda, Nao Inami, Yusuke Kaida, Mitsuru Niwa, Yasuhiro Ito, Takafumi Suda
ICI plus chemotherapy prolonged survival over ICI alone in patients with previously treated advanced NSCLC
Shiqi Mao, Fei Zhou, Yiwei Liu, Shuo Yang, Bin Chen, Jian Xu, Fengying Wu, Xuefei Li, Chao Zhao, Wanying Wang, Qian Liu, Xiaofei Yu, Keyi Jia, Chuchu Shao, Caicun Zhou, Guanghui Gao, Shengxiang Ren
Clinical benefit of continuing pembrolizumab treatment beyond progression in patients with metastatic urothelial carcinoma
Wataru Fukuokaya, Takahiro Kimura, Takafumi Yanagisawa, Shoji Kimura, Shunsuke Tsuzuki, Yuhei Koike, Yuya Iwamoto, Yuki Enei, Masatoshi Tanaka, Fumihiko Urabe, Hajime Onuma, Mariko Honda, Jun Miki, Yu Oyama, Hirokazu Abe, Shin Egawa