Ausgabe 3/2024
Inhalt (20 Artikel)
Identification macrophage signatures in prostate cancer by single-cell sequencing and machine learning
Zhen Kang, Yu-Xuan Zhao, Ren Shun Qian Qiu, Dong-Ning Chen, Qing-Shui Zheng, Xue-Yi Xue, Ning Xu, Yong Wei
Investigating the immunological function of alpha-2-glycoprotein 1, zinc-binding in regulating tumor response in the breast cancer microenvironment
Toru Hanamura, Kozue Yokoyama, Shigehisa Kitano, Hiroshi Kagamu, Makiko Yamashita, Mayako Terao, Takuho Okamura, Nobue Kumaki, Katsuto Hozumi, Takayuki Iwamoto, Chikako Honda, Sasagu Kurozumi, Jennifer K. Richer, Naoki Niikura
Stimulating T cell responses against patient-derived breast cancer cells with neoantigen peptide-loaded peripheral blood mononuclear cells
Natthaporn Sueangoen, Harald Grove, Nisa Chuangchot, Jaturawitt Prasopsiri, Thanyada Rungrotmongkol, Kamonpan Sanachai, Nitchakan Darai, Suyanee Thongchot, Prapat Suriyaphol, Doonyapat Sa-Nguanraksa, Peti Thuwajit, Pa-thai Yenchitsomanus, Chanitra Thuwajit
INDUCE-2: A Phase I/II, open-label, two-part study of feladilimab in combination with tremelimumab in patients with advanced solid tumors
John F. Hilton, Patrick A. Ott, Aaron R. Hansen, Zujun Li, Matthen Mathew, Cristina H. Messina, Vimal Dave, Xiao Ji, Natalie O. Karpinich, Steven Hirschfeld, Marc Ballas, Dan P. Zandberg
Treatment of secondary CNS lymphoma using CD19-targeted chimeric antigen receptor (CAR) T cells
Kathryn Kline, Tim Luetkens, Rima Koka, Michael E. Kallen, Wengen Chen, Haroon Ahmad, Destiny Omili, Thierry Iraguha, Etse Gebru, Xiaoxuan Fan, Alexis Miller, Nishanthini Dishanthan, Jillian M. Baker, Kenneth A. Dietze, Kim G. Hankey, Jean A. Yared, Nancy M. Hardy, Aaron P. Rapoport, Saurabh Dahiya, Djordje Atanackovic
Distinct profiles of proliferating CD8+/TCF1+ T cells and CD163+/PD-L1+ macrophages predict risk of relapse differently among treatment-naïve breast cancer subtypes
Konstantinos Ntostoglou, Sofia D. P. Theodorou, Tanja Proctor, Ilias P. Nikas, Sinclair Awounvo, Athanasia Sepsa, Vassilis Georgoulias, Han Suk Ryu, Ioannis S. Pateras, Christos Kittas
Longitudinal plasma proteomic analysis identifies biomarkers and combinational targets for anti-PD1-resistant cancer patients
Qiaoyun Tan, Ruyun Gao, Xiaomei Zhang, Jianliang Yang, Puyuan Xing, Sheng Yang, Dan Wang, Guibing Wang, Shasha Wang, Jiarui Yao, Zhishang Zhang, Le Tang, Xiaobo Yu, Xiaohong Han, Yuankai Shi
Targeting monoamine oxidase A: a strategy for inhibiting tumor growth with both immune checkpoint inhibitors and immune modulators
Yifan Ma, Hanmu Chen, Hui Li, Zhite Zhao, Qingling An, Changhong Shi
Atovaquone enhances antitumor efficacy of TCR-T therapy by augmentation of ROS-induced ferroptosis in hepatocellular carcinoma
Anan Chen, Zhiwu Yu, Na Ma, Xinyu Lu, Yajing Zhang, Weikang Xu, Yiyue Wang, Jiayi Xie, Yuqi Qin, Guoheng Mo, Sha Wu, Jinlin Hou, Wei Zhu
Low-intensity pulsed ultrasound activated the anti-tumor immunity by irradiating the spleen of mice in 4 T-1 breast cancer
Yi Xia, Meijie Yang, Xinfang Xiao, Wentao Tang, Juan Deng, Liu Wu, Haopeng Xu, Yilin Tang, Wenzhi Chen, Yan Wang
Synergistic combination therapy using cowpea mosaic virus intratumoral immunotherapy and Lag-3 checkpoint blockade
Sweta Karan, Eunkyeong Jung, Christine Boone, Nicole F. Steinmetz
Targeting metabolic sensing switch GPR84 on macrophages for cancer immunotherapy
Jianying Li, Anjun Ma, Ruohan Zhang, Yao Chen, Chelsea Bolyard, Bao Zhao, Cankun Wang, Thera Pich, Wantong Li, Nuo Sun, Qin Ma, Haitao Wen, Steven K. Clinton, William E. Carson III, Zihai Li, Gang Xin
Immunogenic cell death in colorectal cancer: a review of mechanisms and clinical utility
M. De Silva, B. C. Y. Tse, C. I. Diakos, S. Clarke, M. P. Molloy
Retrospective assessment of neoadjuvant camrelizumab combined with induction chemotherapy: efficacy in laryngeal preservation for advanced hypopharyngeal and laryngeal squamous cell carcinoma
Jin Peng, Guangfeng Luo, Yongchao Yu, Kang Ning, Xuekui Liu
Induction immunotherapy plus chemotherapy followed by definitive chemoradiation therapy in locally advanced esophageal squamous cell carcinoma: a propensity-score matched study
Hui-min Lian, Jia-liang Wu, Wei-jian Liufu, Tian-tian Yu, Shao-qing Niu, Yong Bao, Fang Peng
Chemokine CCL21 determines immunotherapy response in hepatocellular carcinoma by affecting neutrophil polarization
Wenxin Xu, Jialei Weng, Minghao Xu, Qiang Zhou, Shaoqing Liu, Zhiqiu Hu, Ning Ren, Chenhao Zhou, Yinghao Shen
Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer
Angisha Basnet, Kaitlyn M. Landreth, Remi Nohoesu, Stell P. Santiago, Werner J. Geldenhuys, Brian A. Boone, Tracy W. Liu
Granzyme B+ B cells detected by single-cell sequencing are associated with prognosis in patients with intrahepatic cholangiocarcinoma following liver transplantation
Ji-Qiao Zhu, Ying Zhu, Man Qi, Ye Zeng, Zhen-Jia Liu, Cheng Ding, Tao Zhang, Xian-Liang Li, Dong-Dong Han, Qiang He
Multiplexed analysis of macrophage polarisation in pulmonary metastases of microsatellite stable colorectal cancer
Topias Karjula, Hanna Elomaa, Sara A. Väyrynen, Teijo Kuopio, Maarit Ahtiainen, Olli Mustonen, Iiris Puro, Anne Niskakangas, Jukka-Pekka Mecklin, Jan Böhm, Erkki-Ville Wirta, Toni T. Seppälä, Eero Sihvo, Fredrik Yannopoulos, Olli Helminen, Juha P. Väyrynen
Toripalimab, a therapeutic monoclonal anti-PD-1 antibody with high binding affinity to PD-1 and enhanced potency to activate human T cells
Narendiran Rajasekaran, Xiaoguang Wang, Sruthi Ravindranathan, Daniel J Chin, Su-Yi Tseng, Scott L Klakamp, Kate Widmann, Varun N Kapoor, Vladimir Vexler, Patricia Keegan, Sheng Yao, Theresa LaVallee, Sanjay D Khare