Ausgabe 1/2024
Inhalt (20 Artikel)
CD204-positive M2-like tumor-associated macrophages increase migration of gastric cancer cells by upregulating miR-210 to reduce NTN4 expression
- Open Access
- Research
Chin-Wang Chen, Hao-Chen Wang, I-Min Tsai, I-Shu Chen, Chang-Jung Chen, Ya-Chin Hou, Yan-Shen Shan
Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression
- Open Access
- Research
Tommaso Montecchi, Giulia Nannini, Domiziana De Tommaso, Chiara Cassioli, Federica Coppola, Maria Novella Ringressi, Fabio Carraro, Antonella Naldini, Antonio Taddei, Giuseppe Marotta, Amedeo Amedei, Cosima T. Baldari, Cristina Ulivieri
PD-L1-positive circulating endothelial progenitor cells associated with immune response to PD-1 blockade in patients with head and neck squamous cell carcinoma
- Research
Nai-Wen Su, Shuen-Han Dai, Kate Hsu, Kuo-Ming Chang, Chun-Chuan Ko, Chen-Wei Kao, Yi-Fang Chang, Caleb G. Chen
Real-world outcomes of nivolumab plus ipilimumab and pembrolizumab with platinum-based chemotherapy in advanced non-small cell lung cancer: a multicenter retrospective comparative study
- Open Access
- Research
Kinnosuke Matsumoto, Takayuki Shiroyama, Motohiro Tamiya, Toshiyuki Minami, Yuhei Kinehara, Akihiro Tamiya, Yasuhiko Suga, Tomoki Kuge, Masahide Mori, Hidekazu Suzuki, Satoshi Tobita, Kiyonobu Ueno, Yoshinobu Namba, Satoshi Tetsumoto, Toshie Niki, Osamu Morimura, Akio Osa, Kazumi Nishino, Izumi Nagatomo, Yoshito Takeda, Takashi Kijima, Atsushi Kumanogoh
Oncolytic adenovirus coding for shedding-resistant MICA enhances immune responses against tumors
- Open Access
- Brief Report
M Costa-Garcia, JJ Rojas, MD Ramos, P Barlabé, P Calvo, J Navas, R Alemany, R Moreno
Generation and assessment of cytokine-induced killer cells for the treatment of colorectal cancer liver metastases
- Open Access
- Research
Celine Man Ying Li, Yoko Tomita, Bimala Dhakal, Teresa Tin, Runhao Li, Josephine A. Wright, Laura Vrbanac, Susan L. Woods, Paul Drew, Timothy Price, Eric Smith, Guy J. Maddern, Kevin Fenix
HDAC6 inhibitor ACY-1215 enhances STAT1 acetylation to block PD-L1 for colorectal cancer immunotherapy
- Open Access
- Research
Yuqing Wen, Shuyu Ye, Zhengshuo Li, Xiaoyue Zhang, Can Liu, Yangge Wu, Run Zheng, Chenxiao Xu, Junrui Tian, Lanjun Shu, Qun Yan, Feiyan Ai, Jian Ma
Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T-cell function while promoting a senescence-associated phenotype
- Open Access
- Brief Report
Russell Towers, Lidia Trombello, Maximilian Fusenig, Antje Tunger, Anna-Lena Baumann, Roberto Savoldelli, Rebekka Wehner, Frederick Fasslrinner, Claudia Arndt, Francesco Dazzi, Malte Von Bonin, Anja Feldmann, Michael P. Bachmann, Manja Wobus, Marc Schmitz, Martin Bornhäuser
Vaccination against neoantigens induced in cross-priming cDC1 in vivo
- Open Access
- Research
Emily S. Clark, Ana Paula Benaduce, Wasif N. Khan, Olivier Martinez, Eli Gilboa
Rescue of NLRC5 expression restores antigen processing machinery in head and neck cancer cells lacking functional STAT1 and p53
- Open Access
- Research
Brendan L. C. Kinney, Sreenivasulu Gunti, Vikash Kansal, Connor J. Parrish, Nabil F. Saba, Yong Teng, Mary Katherine Henry, Fang-Yi Su, Gabriel A. Kwong, Nicole C. Schmitt
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells
- Open Access
- Research
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Predictive value of peripheral blood biomarkers in patients with non-small-cell lung cancer responding to anti-PD-1-based treatment
- Open Access
- Research
Shu Su, Fungjun Chen, Xin Lv, Liang Qi, Zhou Ding, Wei Ren, Ming Wei, Ye Liu, Lixia Yu, Baorui Liu, Lifeng Wang
Allogeneic CAR-T cells with of HLA-A/B and TRAC disruption exhibit promising antitumor capacity against B cell malignancies
- Open Access
- Research
Xinfeng Chen, Binghe Tan, Haizhou Xing, Xuan Zhao, Yu Ping, Zhen Zhang, Jianmin Huang, Xiujuan Shi, Na Zhang, Boxu Lin, Weijie Cao, Xin Li, Xudong Zhang, Ling Li, Zhongxing Jiang, Mingzhi Zhang, Wei Li, Mingyao Liu, Bing Du, Yi Zhang
A novel model for predicting prognosis and response to immunotherapy in nasopharyngeal carcinoma patients
- Open Access
- Research
Ya-Xian Wu, Bo-Yu Tian, Xin-Yuan Ou, Meng Wu, Qi Huang, Run-Kun Han, Xia He, Shu-Lin Chen
Protective effect of low‐intensity pulsed ultrasound on immune checkpoint inhibitor-related myocarditis via fine-tuning CD4+ T-cell differentiation
- Open Access
- Research
Shuai Fu, Zihong Guo, Xiangli Xu, Yifei Li, Stephen Choi, Peng Zhao, Wenqian Shen, Fei Gao, Chao Wang, Shuang Chen, You Li, Jiawei Tian, Ping Sun
Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice
- Open Access
- Research
Akashdip Singh, Eline T. A. M. Mommers-Elshof, Saskia V. Vijver, J. H. Marco Jansen, Susanne Gonder, Robert Jan Lebbink, Dominique Bihan, Richard W. Farndale, Louis Boon, Solomon Langermann, Jeanette H. W. Leusen, Dallas Flies, Linde Meyaard, M. Ines Pascoal Ramos
Ziv-aflibercept plus pembrolizumab in patients with advanced melanoma resistant to anti-PD-1 treatment
- Open Access
- Research
Joanna Baginska, Allison Nau, Ilana Gomez Diaz, Anita Giobbie-Hurder, Jason Weirather, Juliana Vergara, Charlotte Abrecht, Margaret Hallisey, Jenna Dennis, Mariano Severgnini, Julia Huezo, Isabella Marciello, Osama Rahma, Michael Manos, Andrew S. Brohl, Philippe L. Bedard, Daniel J. Renouf, Elad Sharon, Howard Streicher, Patrick A. Ott, Elizabeth I. Buchbinder, F. Stephen Hodi
Phellinus linteus activates Treg cells via FAK to promote M2 macrophage polarization in hepatocellular carcinoma
- Open Access
- Research
Feihua Chen, Mouchun Gong, Dengcheng Weng, Zhaoqing Jin, Guofeng Han, Ziqiang Yang, Junjun Han, Jianjiang Wang
Targeted therapies in retinoblastoma: GD2-directed immunotherapy following autologous stem cell transplantation and evaluation of alternative target B7-H3
- Open Access
- Research
Thomas Eichholz, Florian Heubach, Anne-Marie Arendt, Christian Seitz, Ines B. Brecht, Martin Ebinger, Tim Flaadt, Daniela Süsskind, Lisa Richter, Isabel Hülsenbeck, Leonie Zerweck, Sophia Göricke, Frank Paulsen, Frank Dombrowski, Christian Flotho, Stefan Schönberger, Petra Ketteler, Johannes Schulte, Peter Lang
Coordination of anti-CTLA-4 with whole-brain radiation therapy decreases tumor burden during treatment in a novel syngeneic model of lung cancer brain metastasis
- Open Access
- Research
K. E. Blethen, C. P. Wolford, G. L. Pecar, T. A. Arsiwala, E. Adjeroh, L. P. Dykstra, B. N. Kielkowski, P. R. Lockman
