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Cancer Immunology, Immunotherapy

Ausgabe 7/2021

Inhalt (26 Artikel)

Review

Toward precision immunotherapy using multiplex immunohistochemistry and in silico methods to define the tumor immune microenvironment

Samuel S. Widodo, Ryan A. Hutchinson, Yitong Fang, Stefano Mangiola, Paul J. Neeson, Phillip K. Darcy, Alexander D. Barrow, Christopher M. Hovens, Marija Dinevska, Stanley S. Stylli, Theo Mantamadiotis

Review

Immunologic factors involved in the malignant transformation of endometriosis to endometriosis-associated ovarian carcinoma

S. Leenen, M. Hermens, P. J. de Vos van Steenwijk, R. L. M. Bekkers, E. M. G. van Esch

Original Article

CD47 expression in gastric cancer clinical correlates and association with macrophage infiltration

Mingsu Shi, Yun Gu, Kaifeng Jin, Hanji Fang, Yifan Chen, Yifan Cao, Xin Liu, Kunpeng Lv, Xudong He, Chao Lin, Hao Liu, He Li, Hongyong He, Jing Qin, Ruochen Li, Heng Zhang, Weijuan Zhang

Original Article

A study of the possible role of Fab-glycosylated IgG in tumor immunity

Qian Xu, Xiaodong Deng, Biying Zhang, Chanyuan Zhao, Tao Huang, Yimin Zhang, Zhiming Chen, Jiang Gu

Open Access Original Article

APX005M, a CD40 agonist antibody with unique epitope specificity and Fc receptor binding profile for optimal therapeutic application

Erin L. Filbert, Pia K. Björck, Minu K. Srivastava, Frances R. Bahjat, Xiaodong Yang

Open Access Original Article

Evaluation of cytokines in the tumor microenvironment of lung cancer using bronchoalveolar lavage fluid analysis

Pascal Bezel, Alan Valaperti, Urs Steiner, Dieter Scholtze, Stephan Wieser, Maya Vonow-Eisenring, Andrea Widmer, Benedikt Kowalski, Malcolm Kohler, Daniel P. Franzen

Original Article

Transcriptional regulation of VEGFA expression in T-regulatory cells from breast cancer patients

Kirti Kajal, Sayantan Bose, Abir K. Panda, Dwaipayan Chakraborty, Sreeparna Chakraborty, Subhadip Pati, Tania Sarkar, Subhanki Dhar, Dia Roy, Shilpi Saha, Gaurisankar Sa

Original Article

Impacts of pembrolizumab therapy on immune phenotype in patients with high-grade neuroendocrine neoplasms

Alexander W. MacFarlane IV, Ho-Man Yeung, R. Katherine Alpaugh, Essel Dulaimi, Paul F. Engstrom, Arvind Dasari, Kerry S. Campbell, Namrata Vijayvergia

Original Article

PD-L1 expression in sebaceous carcinomas

Maelle Saliba, Muhammad Shaheen, Rana El Hajj, Fatmeh Abbas, Shaarif Bashir, Umer Nisar Sheikh, Rami Mahfouz, Asif Loya, Ibrahim Khalifeh

Original Article

Identification of new potential antigen recognized by γδT cells in hepatocellular carcinoma

Xueyan Xi, Yang Guo, Min Zhu, Fen Qiu, Feifei Lei, Gang Li, Boyu Du

Open Access Original Article

Real-world outcome of immune checkpoint inhibitors for advanced hepatocellular carcinoma with macrovascular tumor thrombosis

Hong-Ming Tsai, Meng-Zhi Han, Yih-Jyh Lin, Ting-Tsung Chang, Chiung-Yu Chen, Pin-Nan Cheng, Chiao-Hsiung Chuang, I-Chin Wu, Po-Jun Chen, Jui-Wen Kang, Yen-Cheng Chiu, Hung-Chih Chiu, Shih-Chieh Chien, Hsin-Yu Kuo

Original Article

Genetic determinants of immune-related adverse events in patients with melanoma receiving immune checkpoint inhibitors

Noha Abdel-Wahab, Adi Diab, Robert K. Yu, Andrew Futreal, Lindsey A. Criswell, Jean H. Tayar, Ramona Dadu, Vickie Shannon, Sanjay S. Shete, Maria E. Suarez-Almazor

Open Access Original Article

CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma

Pedro Rocha, Ruth Salazar, Jiexin Zhang, Debora Ledesma, Jose L. Solorzano, Barbara Mino, Pamela Villalobos, Hitoshi Dejima, Dzifa Y. Douse, Lixia Diao, Kyle Gregory Mitchell, Xiuning Le, Jianjun Zhang, Annikka Weissferdt, Edwin Parra-Cuentas, Tina Cascone, David C. Rice, Boris Sepesi, Neda Kalhor, Cesar Moran, Ara Vaporciyan, John Heymach, Don L. Gibbons, J. Jack Lee, Humam Kadara, Ignacio Wistuba, Carmen Behrens, Luisa Maren Solis

Open Access Correction

Correction to: CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma

Pedro Rocha, Ruth Salazar, Jiexin Zhang, Debora Ledesma, Jose L. Solorzano, Barbara Mino, Pamela Villalobos, Hitoshi Dejima, Dzifa Y. Douse, Lixia Diao, Kyle Gregory Mitchell, Xiuning Le, Jianjun Zhang, Annikka Weissferdt, Edwin Parra-Cuentas, Tina Cascone, David C. Rice, Boris Sepesi, Neda Kalhor, Cesar Moran, Ara Vaporciyan, John Heymach, Don L. Gibbons, J. Jack Lee, Humam Kadara, Ignacio Wistuba, Carmen Behrens, Luisa Maren Solis

Original Article

Toxicity and effectiveness of CD19 CAR T therapy in children with high-burden central nervous system refractory B-ALL

Yue Tan, Jing Pan, Biping Deng, Zhuojun Ling, Weiliang Song, Jinlong Xu, Jiajia Duan, Zelin Wang, Xinjian Yu, Alex H. Chang, Xiaoming Feng

Original Article

Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values

A. Reum Kim, Kyu Sung Choi, Min-Sung Kim, Kyung-Min Kim, Ho Kang, Sojin Kim, Tamrin Chowdhury, Hyeon Jong Yu, Chae Eun Lee, Joo Ho Lee, Soon-Tae Lee, Jae Kyung Won, Jin Wook Kim, Yong-Hwy Kim, Tae Min Kim, Sung-Hye Park, Seung Hong Choi, Eui-Cheol Shin, Chul-Kee Park

Original Article

Thyroid dysfunction induced by immune checkpoint inhibitors is associated with a better progression-free survival and overall survival in non-small cell lung cancer: an original cohort study

Philippe Thuillier, Claire Joly, Zarrin Alavi, Geneviève Crouzeix, Renaud Descourt, Gilles Quere, Véronique Kerlan, Nathalie Roudaut

Original Article

Comparative analysis of the tumor immune-microenvironment of primary and brain metastases of non-small-cell lung cancer reveals organ-specific and EGFR mutation-dependent unique immune landscape

Seung Geun Song, Sehui Kim, Jaemoon Koh, Jeemin Yim, Bogyeong Han, Young A. Kim, Yoon Kyung Jeon, Doo Hyun Chung

Open Access Original Article

A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment

Dordi Lea, Martin Watson, Ivar Skaland, Hanne R. Hagland, Melinda Lillesand, Einar Gudlaugsson, Kjetil Søreide

Original Article

CD27 enhances the killing effect of CAR T cells targeting trophoblast cell surface antigen 2 in the treatment of solid tumors

Huanpeng Chen, Fengjiao Wei, Meng Yin, Qingyu Zhao, Zhonghua Liu, Bolan Yu, Zhaofeng Huang

Original Article

Stimulation of an anti-tumor immune response with “chromatin-damaging” therapy

Minhui Chen, Craig M. Brackett, Lyudmila G. Burdelya, Achamaporn Punnanitinont, Santosh K. Patnaik, Junko Matsuzaki, Adekunle O. Odunsi, Andrei V. Gudkov, Anurag K. Singh, Elizabeth A. Repasky, Katerina V. Gurova

Open Access Research Report

Activity of ipilimumab plus nivolumab in avelumab-refractory Merkel cell carcinoma

Valerie Glutsch, Hermann Kneitz, Anja Gesierich, Matthias Goebeler, Sebastian Haferkamp, Jürgen C. Becker, Selma Ugurel, Bastian Schilling

Open Access Research Report

Early changes in the circulating T cells are associated with clinical outcomes after PD-L1 blockade by durvalumab in advanced NSCLC patients

Elliot Naidus, Jerome Bouquet, David Y. Oh, Timothy J. Looney, Hai Yang, Lawrence Fong, Nathan E. Standifer, Li Zhang

Update Onkologie

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