Ausgabe 7/2021
Inhalt (26 Artikel)
The subtle interplay between gamma delta T lymphocytes and dendritic cells: is there a role for a therapeutic cancer vaccine in the era of combinatorial strategies?
- Review
Domenico Galati, Serena Zanotta, Marialuisa Bocchino, Rosaria De Filippi, Antonio Pinto
Toward precision immunotherapy using multiplex immunohistochemistry and in silico methods to define the tumor immune microenvironment
- Review
Samuel S. Widodo, Ryan A. Hutchinson, Yitong Fang, Stefano Mangiola, Paul J. Neeson, Phillip K. Darcy, Alexander D. Barrow, Christopher M. Hovens, Marija Dinevska, Stanley S. Stylli, Theo Mantamadiotis
Immunologic factors involved in the malignant transformation of endometriosis to endometriosis-associated ovarian carcinoma
- Review
S. Leenen, M. Hermens, P. J. de Vos van Steenwijk, R. L. M. Bekkers, E. M. G. van Esch
CD47 expression in gastric cancer clinical correlates and association with macrophage infiltration
- Original Article
Mingsu Shi, Yun Gu, Kaifeng Jin, Hanji Fang, Yifan Chen, Yifan Cao, Xin Liu, Kunpeng Lv, Xudong He, Chao Lin, Hao Liu, He Li, Hongyong He, Jing Qin, Ruochen Li, Heng Zhang, Weijuan Zhang
A study of the possible role of Fab-glycosylated IgG in tumor immunity
- Original Article
Qian Xu, Xiaodong Deng, Biying Zhang, Chanyuan Zhao, Tao Huang, Yimin Zhang, Zhiming Chen, Jiang Gu
APX005M, a CD40 agonist antibody with unique epitope specificity and Fc receptor binding profile for optimal therapeutic application
- Open Access
- Original Article
Erin L. Filbert, Pia K. Björck, Minu K. Srivastava, Frances R. Bahjat, Xiaodong Yang
Evaluation of cytokines in the tumor microenvironment of lung cancer using bronchoalveolar lavage fluid analysis
- Open Access
- Original Article
Pascal Bezel, Alan Valaperti, Urs Steiner, Dieter Scholtze, Stephan Wieser, Maya Vonow-Eisenring, Andrea Widmer, Benedikt Kowalski, Malcolm Kohler, Daniel P. Franzen
Transcriptional regulation of VEGFA expression in T-regulatory cells from breast cancer patients
- Original Article
Kirti Kajal, Sayantan Bose, Abir K. Panda, Dwaipayan Chakraborty, Sreeparna Chakraborty, Subhadip Pati, Tania Sarkar, Subhanki Dhar, Dia Roy, Shilpi Saha, Gaurisankar Sa
Impacts of pembrolizumab therapy on immune phenotype in patients with high-grade neuroendocrine neoplasms
- Original Article
Alexander W. MacFarlane IV, Ho-Man Yeung, R. Katherine Alpaugh, Essel Dulaimi, Paul F. Engstrom, Arvind Dasari, Kerry S. Campbell, Namrata Vijayvergia
PD-L1 expression in sebaceous carcinomas
- Original Article
Maelle Saliba, Muhammad Shaheen, Rana El Hajj, Fatmeh Abbas, Shaarif Bashir, Umer Nisar Sheikh, Rami Mahfouz, Asif Loya, Ibrahim Khalifeh
Identification of new potential antigen recognized by γδT cells in hepatocellular carcinoma
- Original Article
Xueyan Xi, Yang Guo, Min Zhu, Fen Qiu, Feifei Lei, Gang Li, Boyu Du
Real-world outcome of immune checkpoint inhibitors for advanced hepatocellular carcinoma with macrovascular tumor thrombosis
- Open Access
- Original Article
Hong-Ming Tsai, Meng-Zhi Han, Yih-Jyh Lin, Ting-Tsung Chang, Chiung-Yu Chen, Pin-Nan Cheng, Chiao-Hsiung Chuang, I-Chin Wu, Po-Jun Chen, Jui-Wen Kang, Yen-Cheng Chiu, Hung-Chih Chiu, Shih-Chieh Chien, Hsin-Yu Kuo
Genetic determinants of immune-related adverse events in patients with melanoma receiving immune checkpoint inhibitors
- Original Article
Noha Abdel-Wahab, Adi Diab, Robert K. Yu, Andrew Futreal, Lindsey A. Criswell, Jean H. Tayar, Ramona Dadu, Vickie Shannon, Sanjay S. Shete, Maria E. Suarez-Almazor
Run for your life: an integrated virtual tissue platform for incorporating exercise oncology into immunotherapy
- Original Article
Josua Aponte Serrano, Amit Hagar
CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma
- Open Access
- Original Article
Pedro Rocha, Ruth Salazar, Jiexin Zhang, Debora Ledesma, Jose L. Solorzano, Barbara Mino, Pamela Villalobos, Hitoshi Dejima, Dzifa Y. Douse, Lixia Diao, Kyle Gregory Mitchell, Xiuning Le, Jianjun Zhang, Annikka Weissferdt, Edwin Parra-Cuentas, Tina Cascone, David C. Rice, Boris Sepesi, Neda Kalhor, Cesar Moran, Ara Vaporciyan, John Heymach, Don L. Gibbons, J. Jack Lee, Humam Kadara, Ignacio Wistuba, Carmen Behrens, Luisa Maren Solis
Correction to: CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma
- Open Access
- Correction
Pedro Rocha, Ruth Salazar, Jiexin Zhang, Debora Ledesma, Jose L. Solorzano, Barbara Mino, Pamela Villalobos, Hitoshi Dejima, Dzifa Y. Douse, Lixia Diao, Kyle Gregory Mitchell, Xiuning Le, Jianjun Zhang, Annikka Weissferdt, Edwin Parra-Cuentas, Tina Cascone, David C. Rice, Boris Sepesi, Neda Kalhor, Cesar Moran, Ara Vaporciyan, John Heymach, Don L. Gibbons, J. Jack Lee, Humam Kadara, Ignacio Wistuba, Carmen Behrens, Luisa Maren Solis
Toxicity and effectiveness of CD19 CAR T therapy in children with high-burden central nervous system refractory B-ALL
- Original Article
Yue Tan, Jing Pan, Biping Deng, Zhuojun Ling, Weiliang Song, Jinlong Xu, Jiajia Duan, Zelin Wang, Xinjian Yu, Alex H. Chang, Xiaoming Feng
Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values
- Original Article
A. Reum Kim, Kyu Sung Choi, Min-Sung Kim, Kyung-Min Kim, Ho Kang, Sojin Kim, Tamrin Chowdhury, Hyeon Jong Yu, Chae Eun Lee, Joo Ho Lee, Soon-Tae Lee, Jae Kyung Won, Jin Wook Kim, Yong-Hwy Kim, Tae Min Kim, Sung-Hye Park, Seung Hong Choi, Eui-Cheol Shin, Chul-Kee Park
Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to anti-vascular endothelial growth factor agents and anti-PD-1/Anti-CTLA4 antibodies and shorter survival
- Open Access
- Original Article
Takao Kamai, Toshiki Kijima, Toyonori Tsuzuki, Akinori Nukui, Hideyuki Abe, Kyoko Arai, Ken-Ichiro Yoshida
Thyroid dysfunction induced by immune checkpoint inhibitors is associated with a better progression-free survival and overall survival in non-small cell lung cancer: an original cohort study
- Original Article
Philippe Thuillier, Claire Joly, Zarrin Alavi, Geneviève Crouzeix, Renaud Descourt, Gilles Quere, Véronique Kerlan, Nathalie Roudaut
Comparative analysis of the tumor immune-microenvironment of primary and brain metastases of non-small-cell lung cancer reveals organ-specific and EGFR mutation-dependent unique immune landscape
- Original Article
Seung Geun Song, Sehui Kim, Jaemoon Koh, Jeemin Yim, Bogyeong Han, Young A. Kim, Yoon Kyung Jeon, Doo Hyun Chung
A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment
- Open Access
- Original Article
Dordi Lea, Martin Watson, Ivar Skaland, Hanne R. Hagland, Melinda Lillesand, Einar Gudlaugsson, Kjetil Søreide
CD27 enhances the killing effect of CAR T cells targeting trophoblast cell surface antigen 2 in the treatment of solid tumors
- Original Article
Huanpeng Chen, Fengjiao Wei, Meng Yin, Qingyu Zhao, Zhonghua Liu, Bolan Yu, Zhaofeng Huang
Stimulation of an anti-tumor immune response with “chromatin-damaging” therapy
- Original Article
Minhui Chen, Craig M. Brackett, Lyudmila G. Burdelya, Achamaporn Punnanitinont, Santosh K. Patnaik, Junko Matsuzaki, Adekunle O. Odunsi, Andrei V. Gudkov, Anurag K. Singh, Elizabeth A. Repasky, Katerina V. Gurova
Activity of ipilimumab plus nivolumab in avelumab-refractory Merkel cell carcinoma
- Open Access
- Research Report
Valerie Glutsch, Hermann Kneitz, Anja Gesierich, Matthias Goebeler, Sebastian Haferkamp, Jürgen C. Becker, Selma Ugurel, Bastian Schilling
Early changes in the circulating T cells are associated with clinical outcomes after PD-L1 blockade by durvalumab in advanced NSCLC patients
- Open Access
- Research Report
Elliot Naidus, Jerome Bouquet, David Y. Oh, Timothy J. Looney, Hai Yang, Lawrence Fong, Nathan E. Standifer, Li Zhang