Ausgabe 9/2015
Inhalt (13 Artikel)
Immune checkpoint targeting as anti-cancer immunotherapy: promises, questions, challenges and the need for predictive biomarkers at ASCO 2015
Hardev Pandha, Graham Pawelec
Increased CCL17 serum levels are associated with improved survival in advanced melanoma
Benjamin Weide, Nicolas Allgaier, Andreas Hector, Andrea Forschner, Ulrike Leiter, Thomas K. Eigentler, Claus Garbe, Dominik Hartl
Phase I/II study of adjuvant immunotherapy with sentinel lymph node T lymphocytes in patients with colorectal cancer
Yun-Huan Zhen, Xiao-Hui Liu, Yuan Yang, Bo Li, Jing-Ling Tang, Qiang-Xing Zeng, Jie Hu, Xing-Nan Zeng, Lu Zhang, Ze-Jun Wang, Xiao-Yun Li, Hui-Xin Ge, Ola Winqvist, Ping-Sheng Hu, Jin Xiu
Anti-PD-L1 prolongs survival and triggers T cell but not humoral anti-tumor immune responses in a human MUC1-expressing preclinical ovarian cancer model
Jyothi Thyagabhavan Mony, Lixin Zhang, Tianzhou Ma, Shannon Grabosch, Tejas S. Tirodkar, Joan Brozick, George Tseng, Esther Elishaev, Robert P. Edwards, Xin Huang, Anda M. Vlad
Local and systemic XAGE-1b-specific immunity in patients with lung adenocarcinoma
Mehrdad Talebian Yazdi, Nikki M. Loof, Kees L. M. C. Franken, Christian Taube, Jaap Oostendorp, Pieter S. Hiemstra, Marij J. P. Welters, Sjoerd H. van der Burg
A pilot study in prostate cancer patients treated with the AE37 Ii-key-HER-2/neu polypeptide vaccine suggests that HLA-A*24 and HLA-DRB1*11 alleles may be prognostic and predictive biomarkers for clinical benefit
Eleftheria A. Anastasopoulou, Ioannis F. Voutsas, Theodora Keramitsoglou, Cécile Gouttefangeas, Hubert Kalbacher, Anastasios Thanos, Michael Papamichail, Sonia A. Perez, Constantin N. Baxevanis
Modulating the innate immune activity in murine tumor microenvironment by a combination of inducer molecules attached to microparticles
Ehud Shahar, Raphael Gorodetsky, Elina Aizenshtein, Lior Lalush, Jacob Pitcovski
Genetic susceptibility to cervical squamous cell carcinoma is associated with HLA-DPB1 polymorphisms in Taiwanese women
Yuh-Cheng Yang, Tzu-Yang Chang, Tze-Chien Chen, Wen-Shan Lin, Shih-Chuan Chang, Yann-Jinn Lee
Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients
Maria Grazia Cusi, Cirino Botta, Pierpaolo Pastina, Maria Grazia Rossetti, Elena Dreassi, Giacomo Maria Guidelli, Antonella Fioravanti, Elodia Claudia Martino, Claudia Gandolfo, Marco Pagliuchi, Assunta Basile, Salvatore Francesco Carbone, Veronica Ricci, Lucia Micheli, Pierfrancesco Tassone, Pierosandro Tagliaferri, Luigi Pirtoli, Pierpaolo Correale
The TLR-2/TLR-6 agonist macrophage-activating lipopeptide-2 augments human NK cell cytotoxicity when PGE2 production by monocytes is inhibited by a COX-2 blocker
Christina Müller, Dejene M. Tufa, Debanjana Chatterjee, Peter F. Mühlradt, Reinhold E. Schmidt, Roland Jacobs
Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer
Joseph D. Phillips, Lawrence M. Knab, Nichole R. Blatner, Leila Haghi, Malcolm M. DeCamp, Shari L. Meyerson, Michael J. Heiferman, Jeffrey R. Heiferman, Fotini Gounari, David J. Bentrem, Khashayarsha Khazaie
Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas
Ellen H. de Moll, Yichun Fu, Yingzhi Qian, Sara H. Perkins, Shira Wieder, Sacha Gnjatic, Romain Remark, Sebastian G. Bernardo, Marina Moskalenko, Jonathan Yao, Tammie Ferringer, Rui Chang, Jerry Chipuk, Basil A. Horst, Miriam B. Birge, Robert G. Phelps, Yvonne M. Saenger
Inhibition of tumor progression during allergic airway inflammation in a murine model: significant role of TGF-β
Belen Tirado-Rodriguez, Guillermina Baay-Guzman, Rogelio Hernandez-Pando, Gabriela Antonio-Andres, Mario I. Vega, Leticia Rocha-Zavaleta, Laura C. Bonifaz, Sara Huerta-Yepez