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Current Pain and Headache Reports
Erschienen in: Current Pain and Headache Reports 11/2014

01.11.2014 | Neuropathic Pain (E Eisenberg, Section Editor)

Cancer Treatment-Related Neuropathic Pain Syndromes—Epidemiology and Treatment: An Update

verfasst von: Ellen M. Lavoie Smith, Celia M. Bridges, Grace Kanzawa, Robert Knoerl, James P. Kelly IV, Anna Berezovsky, Charis Woo

Erschienen in: Current Pain and Headache Reports | Ausgabe 11/2014

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Abstract

Cancer treatment-related chronic neuropathic pain (NP) is a pervasive and distressing problem that negatively influences function and quality of life for countless cancer survivors. It occurs because of cancer treatment-induced damage to peripheral and central nervous system structures. NP becomes chronic when pain signal transmission persists, eventually sensitizing neurons in the dorsal horn and other pain-processing regions in the central nervous system. Frequently overlooked, NP due to cancer treatment has been understudied. Consequently, only a few pharmacologic interventions have been shown to be effective based on the results of randomized controlled trials. Future research designed to explore pathophysiologic mechanisms and effective mechanism-targeted interventions is sorely needed.
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Metadaten
Titel
Cancer Treatment-Related Neuropathic Pain Syndromes—Epidemiology and Treatment: An Update
verfasst von
Ellen M. Lavoie Smith
Celia M. Bridges
Grace Kanzawa
Robert Knoerl
James P. Kelly IV
Anna Berezovsky
Charis Woo
Publikationsdatum
01.11.2014
Verlag
Springer US
Erschienen in
Current Pain and Headache Reports / Ausgabe 11/2014
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-014-0459-7

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