Erschienen in:
30.01.2019 | Editorial
Cerebral complications of solid organ transplantation
verfasst von:
R. Sonneville, E. Mariotte, M. C. Brouwer
Erschienen in:
Intensive Care Medicine
|
Ausgabe 3/2019
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Excerpt
Solid organ transplantation (SOT) is a highly effective treatment in patients with end-stage organ failure, but is associated with a substantial risk of complications, including neurologic complications. Depending on the type of SOT and evaluated time frame, neurologic complications are described in between 10 and 21% of kidney transplant patients [
1] and 33% of liver transplant patients in the perioperative period [
2] and in 85% of heart transplant patients during 18 years of follow-up [
3]. The spectrum of complications is broad, including postoperative delirium, peri-transplantation stroke, drug toxicity, central nervous system (CNS) infections and post-transplantation CNS lymphomas [
4]. Here, we provide a practical approach to management of major neurologic complications in SOT patients admitted to the ICU. …