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Erschienen in: Clinical Neuroradiology 4/2019

23.08.2018 | Original Article

Cervical MRI Rating Scale: Innovative Approach to Differentiate between Demyelinating and Disc Lesions

verfasst von: Uri Givon, Chen Hoffman, Alon Friedlander, Anat Achiron

Erschienen in: Clinical Neuroradiology | Ausgabe 4/2019

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Abstract

Purpose

The difficult differentiation between multiple sclerosis (MS) lesions and cervical spondylotic myelopathy (CSM) in the cervical spine is well known. The magnetic resonance imaging (MRI) appearance of both lesions is similar, and clinical parameters are usually used for diagnosis. The objective was to establish a reliable radiologic paradigm for diagnosis of demyelinating lesions in the cervical spine.

Methods

The MRI studies of 33 patients with MS (42 lesions) and 55 patients with CSM (60 lesions) were obtained. Lesions were evaluated for vertebral level, lesion location and size in the sagittal and axial planes, cord thickness, well-defined or ill-defined borders, presence of edema and enhancement with gadolinium. Significant differences were used to create a paradigm, which was used for the evaluation of a different group of 32 MRIs with 42 concomitant MS and CSM lesions.

Results

Significant differences were seen in the level, location within the cord in both planes, lesion size, cord thickness and lesion border. The MS lesions were well-defined lesions found in C1–3, posterior in the sagittal plane, central in the axial plane, with a normal or increased cord thickness. Good agreement was seen in the validation stage.

Conclusion

The new CSM-MS lesion score allows accurate diagnosis of demyelinating lesions in the cervical spine vs. CSM lesions.
Literatur
1.
Zurück zum Zitat Chong AL, Chandra RV, Chuah KC, Roberts EL, Stuckey SL. Proton Density MRI Increases Detection of Cervical Spinal Cord Multiple Sclerosis Lesions Compared with T2-Weighted Fast Spin-Echo. AJNR Am J Neuroradiol. 2016;37:180-4.CrossRefPubMed Chong AL, Chandra RV, Chuah KC, Roberts EL, Stuckey SL. Proton Density MRI Increases Detection of Cervical Spinal Cord Multiple Sclerosis Lesions Compared with T2-Weighted Fast Spin-Echo. AJNR Am J Neuroradiol. 2016;37:180-4.CrossRefPubMed
2.
Zurück zum Zitat Dula AN, Pawate S, Dortch RD, Barry RL, George-Durrett KM, Lyttle BD, Dethrage LM, Gore JC, Smith SA. Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T. Mult Scler. 2016;22:320–8.CrossRef Dula AN, Pawate S, Dortch RD, Barry RL, George-Durrett KM, Lyttle BD, Dethrage LM, Gore JC, Smith SA. Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T. Mult Scler. 2016;22:320–8.CrossRef
3.
Zurück zum Zitat Hittmair K, Mallek R, Prayer D, Schindler EG, Kollegger H. Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences. AJNR Am J Neuroradiol. 1996;17:1555–65.PubMed Hittmair K, Mallek R, Prayer D, Schindler EG, Kollegger H. Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences. AJNR Am J Neuroradiol. 1996;17:1555–65.PubMed
4.
Zurück zum Zitat Ronthal M. On the coincidence of cervical spondylosis and multiple sclerosis. Clin Neurol Neurosurg. 2006;108:275–7.CrossRef Ronthal M. On the coincidence of cervical spondylosis and multiple sclerosis. Clin Neurol Neurosurg. 2006;108:275–7.CrossRef
5.
Zurück zum Zitat Bashir K, Hadley MN, Whitaker JN. Surgery for spinal cord compression in multiple sclerosis. Curr Opin Neurol. 2001;14:765–9.CrossRef Bashir K, Hadley MN, Whitaker JN. Surgery for spinal cord compression in multiple sclerosis. Curr Opin Neurol. 2001;14:765–9.CrossRef
6.
Zurück zum Zitat Bashir K, Cai CY, Moore TA 2nd, Whitaker JN, Hadley MN. Surgery for cervical spinal cord compression in patients with multiple sclerosis. Neurosurgery. 2000;47:637–42; discussion 642–3.PubMed Bashir K, Cai CY, Moore TA 2nd, Whitaker JN, Hadley MN. Surgery for cervical spinal cord compression in patients with multiple sclerosis. Neurosurgery. 2000;47:637–42; discussion 642–3.PubMed
7.
Zurück zum Zitat Tan LA, Kasliwal MK, Muth CC, Stefoski D, Traynelis VC. Is cervical decompression beneficial in patients with coexistent cervical stenosis and multiple sclerosis? J Clin Neurosci. 2014;21:2189–93.CrossRef Tan LA, Kasliwal MK, Muth CC, Stefoski D, Traynelis VC. Is cervical decompression beneficial in patients with coexistent cervical stenosis and multiple sclerosis? J Clin Neurosci. 2014;21:2189–93.CrossRef
8.
Zurück zum Zitat Lubelski D, Alvin MD, Silverstein M, Senol N, Abdullah KG, Benzel EC, Mroz TE. Quality of life outcomes following surgery for patients with coexistent cervical stenosis and multiple sclerosis. Eur Spine J. 2014;23:1699–704.CrossRef Lubelski D, Alvin MD, Silverstein M, Senol N, Abdullah KG, Benzel EC, Mroz TE. Quality of life outcomes following surgery for patients with coexistent cervical stenosis and multiple sclerosis. Eur Spine J. 2014;23:1699–704.CrossRef
9.
Zurück zum Zitat Lubelski D, Abdullah KG, Alvin MD, Wang TY, Nowacki AS, Steinmetz MP, Ransohoff RM, Benzel EC, Mroz TE.Clinical outcomes following surgical management of coexistent cervical stenosis and multiple sclerosis: a cohort-controlled analysis. Spine J. 2014;14:331–7.CrossRef Lubelski D, Abdullah KG, Alvin MD, Wang TY, Nowacki AS, Steinmetz MP, Ransohoff RM, Benzel EC, Mroz TE.Clinical outcomes following surgical management of coexistent cervical stenosis and multiple sclerosis: a cohort-controlled analysis. Spine J. 2014;14:331–7.CrossRef
10.
Zurück zum Zitat Harrop JS, Naroji S, Maltenfort M, Anderson DG, Albert T, Ratliff JK, Ponnappan RK, Rihn JA, Smith HE, Hilibrand A, Sharan AD, Vaccaro A. Cervical myelopathy: a clinical and radiographic evaluation and correlation to cervical spondylotic myelopathy. Spine (Phila Pa 1976). 2010;35:620–4.CrossRef Harrop JS, Naroji S, Maltenfort M, Anderson DG, Albert T, Ratliff JK, Ponnappan RK, Rihn JA, Smith HE, Hilibrand A, Sharan AD, Vaccaro A. Cervical myelopathy: a clinical and radiographic evaluation and correlation to cervical spondylotic myelopathy. Spine (Phila Pa 1976). 2010;35:620–4.CrossRef
11.
Zurück zum Zitat Kim HJ, Tetreault LA, Massicotte EM, Arnold PM, Skelly AC, Brodt ED, Riew KD. Differential diagnosis for cervical spondylotic myelopathy: literature review. Spine (Phila Pa 1976). 2013;38(22 Suppl 1):S78–88.CrossRef Kim HJ, Tetreault LA, Massicotte EM, Arnold PM, Skelly AC, Brodt ED, Riew KD. Differential diagnosis for cervical spondylotic myelopathy: literature review. Spine (Phila Pa 1976). 2013;38(22 Suppl 1):S78–88.CrossRef
12.
Zurück zum Zitat Brain R, Wilkinson M. The association of cervical spondylosis and disseminated sclerosis. Brain. 1957;80:456–78.CrossRef Brain R, Wilkinson M. The association of cervical spondylosis and disseminated sclerosis. Brain. 1957;80:456–78.CrossRef
13.
Zurück zum Zitat Lebl DR, Bono CM. Update on the diagnosis and management of cervical spondylotic myelopathy. J Am Acad Orthop Surg. 2015;23:648–60.CrossRef Lebl DR, Bono CM. Update on the diagnosis and management of cervical spondylotic myelopathy. J Am Acad Orthop Surg. 2015;23:648–60.CrossRef
14.
Zurück zum Zitat Fehlings MG, Tetreault LA, Wilson JR, Skelly AC. Cervical spondylotic myelopathy: current state of the art and future directions. Spine (Phila Pa 1976). 2013;38(22 Suppl 1):S1–8.CrossRef Fehlings MG, Tetreault LA, Wilson JR, Skelly AC. Cervical spondylotic myelopathy: current state of the art and future directions. Spine (Phila Pa 1976). 2013;38(22 Suppl 1):S1–8.CrossRef
Metadaten
Titel
Cervical MRI Rating Scale: Innovative Approach to Differentiate between Demyelinating and Disc Lesions
verfasst von
Uri Givon
Chen Hoffman
Alon Friedlander
Anat Achiron
Publikationsdatum
23.08.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Neuroradiology / Ausgabe 4/2019
Print ISSN: 1869-1439
Elektronische ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-018-0721-1

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