Ausgabe 11/2022
Inhalt (11 Artikel)
Clinical Pharmacokinetics and Pharmacodynamics of Rucaparib
Mingxiang Liao, Jeri Beltman, Heidi Giordano, Thomas C. Harding, Lara Maloney, Andrew D. Simmons, Jim J. Xiao
Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resistance to Anti-Cancer Agents: A Review on the Pharmacogenomics Aspect
Gera Narendra, Shalki Choudhary, Baddipadige Raju, Himanshu Verma, Om Silakari
The Cytokine Release Syndrome and/or the Proinflammatory Cytokines as Underlying Mechanisms of Downregulation of Drug Metabolism and Drug Transport: A Systematic Review of the Clinical Pharmacokinetics of Victim Drugs of this Drug–Disease Interaction Under Different Clinical Conditions
Milo Gatti, Federico Pea
Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates
Wan-Yu Chu, Karel Allegaert, Thomas P. C. Dorlo, Alwin D. R. Huitema, Axel R. Franz, Mario Rüdiger, Laura Nijstad, Kim Annink, Christian Maiwald, Michael Schroth, Anja Hagen, Loubna el Bakkali, Mirjam M. van Weisenbruch, Christian F. Poets, Manon Benders, Frank van Bel, Karel Allegaert, Gunnar Naulaers, Dirk Bassler, Katrin Klebermass-Schrehof, Maximo Vento, Hercilia Guimaraes, Tom Stiris, Isabella Mauro, Marjo Metsäranta, Sampsa Vanhatalo, Jan Mazela, Tuuli Metsvaht, Roselinda van der Vlugt-Meijer
Optimising the Nadroparin Dose for Thromboprophylaxis During Hemodialysis by Developing a Population Pharmacodynamic Model Using Anti-Xa Levels
Tessa C. C. Jaspers, Charlotte E. Meijer, Louis Jean Vleming, Casper F. M. Franssen, Jeroen Diepstraten, Michael V. Lukens, Patricia M. L. A. van den Bemt, Barbara Maat, Nakisa Khorsand, Daniël J. Touw, Jeroen V. Koomen
Pharmacokinetic Study of Conjugated Equine Estrogens in Healthy Chinese Postmenopausal Women Using a Parallel Two-Column LC–MS/MS Method
Meiyun Shi, Lei Yin, Yantong Sun, Can Wang, Lanlan Cai, Tinglan Zhang, Xiaotong Zhou, J. Paul Fawcett, Xiaoli Gao, Jingkai Gu
Characterizing Absorption Properties of Dispersible Pretomanid Tablets Using Population Pharmacokinetic Modelling
Yuanxi Zou, Jerry Nedelman, Antonio Lombardi, Frances Pappas, Mats O. Karlsson, Elin M. Svensson
Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion
Yomna M. Nassar, Nicolas Hohmann, Robin Michelet, Katharina Gottwalt, Andreas D. Meid, Jürgen Burhenne, Wilhelm Huisinga, Walter E. Haefeli, Gerd Mikus, Charlotte Kloft
Meropenem Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children Receiving Continuous Renal Replacement Therapy
Michael Thy, Saik Urien, Naim Bouazza, Frantz Foissac, Inès Gana, Emmanuelle Bille, Agathe Béranger, Julie Toubiana, Romain Berthaud, Fabrice Lesage, Sylvain Renolleau, Jean-Marc Tréluyer, Sihem Benaboud, Mehdi Oualha
Evaluation of Absorption and Metabolism-Based DDI Potential of Pexidartinib in Healthy Subjects
Hamim Zahir, Jonathan Greenberg, Dale Shuster, Ching Hsu, Kengo Watanabe, Frank LaCreta
Correction to: Predicting Drug–Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling
Maiara Camotti Montanha, Francesc Fabrega, Alice Howarth, Nicolas Cottura, Hannah Kinvig, Fazila Bunglawala, Andrew Lloyd, Paolo Denti, Catriona Waitt, Marco Siccardi