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Endocrine Pathology

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01.03.2009

Collision Tumors of the Sella: Craniopharyngioma and Silent Pituitary Adenoma Subtype 3: Case Report

verfasst von: Olga Moshkin, Bernd W. Scheithauer, Luis V. Syro, Alejandro Velasquez, Eva Horvath, Kalman Kovacs

Erschienen in: Endocrine Pathology | Ausgabe 1/2009

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Abstract

Collision tumors of the sella turcica are rare and consist mainly of more than one type of pituitary adenoma, usually a corticotropin- and a prolactin-producing adenoma. The association of a craniopharyngioma and a pituitary adenoma is rare. Herein, we report the first case of an association between craniopharyngioma and silent pituitary adenoma subtype 3. It involved a 12-year-old boy who underwent a frontal craniotomy with surgical removal of a calcified sellar tumor. Histology revealed an adamantinomatous craniopharyngioma; however, by electron microscopy, there was conclusive evidence of adenoma cells showing the ultrastructural features of silent pituitary adenoma subtype 3. Endocrine and neuroimaging as well as detailed immunohistochemical and ultrastructural studies were undertaken. The literature is also reviewed.

Sautner D, Saeger W, Ludecke DK. Tumors of the sellar region mimicking pituitary adenomas. Exp Clin Endocrinol 101(5):283–9, 1993.PubMed

FitzPatrick M, Tartaglino LM, Hollander MD, Zimmerman RA, Flanders AE. Imaging of sellar and parasellar pathology. Radiol Clin North Am 37(1):101–21, 1999. doi:10.1016/S0033-8389(05)70081-6.PubMedCrossRef

Karavitaki N, Brufani C, Warner JT, Adams CB, Richards P, Ansorge O, Shine B, Turner HE, Wass JA. Craniopharyngiomas in children and adults: systematic analysis of 121 cases with long-term follow-up. Clin Endocrinol (Oxf) 62(4):397–409, 2005. doi:10.1111/j.1365-2265.2005.02231.x.CrossRef

Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM. The descriptive epidemiology of craniopharyngioma. J Neurosurg 89(4):547–51, 1998.PubMed

Lafferty AR, Chrousos GP. Pituitary tumors in children and adolescents. J Clin Endocrinol Metab 84(12):4317–23, 1999. doi:10.1210/jc.84.12.4317.PubMedCrossRef

Aksenova MA, Korshunov AG. Hyperprolactinaemia in craniopharyngiomas. Zh Vopr Neirokhir Im NN Burdenko (2):26–29, 1989.

Asari J, Yamanobe K, Sasaki T, Yamao N, Kodama N. A case of prolactinoma associated with craniopharyngioma. No Shinkei Geka 15(12):1313–8, 1987.PubMed

Cusimano MD, Kovacs K, Bilbao JM, Tucker WS, Singer W. Suprasellar craniopharyngioma associated with hyperprolactinaemia, pituitary lactotroph hyperplasia, and microprolactinoma. Case report. J Neurosurg 69(4):620–3, 1988.PubMed

Karavitaki N, Scheithauer BW, Watt J, Ansorge O, Moschopoulos M, Llaguno AV, Wass JA. Collision lesions of the sella: co-existence of craniopharyngioma with gonadotroph adenoma and of Rathke’s cleft cyst with corticotroph adenoma. Pituitary 11(3):317–23, 2008. doi:10.1007/s11102-007-0070-6.PubMedCrossRef

10.

Prabhakar V, Rao BD, Subramanyam MV. Pituitary adenoma associated with craniopharyngioma. J Pathol 103(3):185–7, 1971. doi:10.1002/path.1711030307.PubMedCrossRef

11.

Sano K. Pituitary adenoma and craniopharyngioma. No To Shinkei 21(12):1326–9, 1969.PubMed

12.

Shishkina VL, Kasumova S, Snigireva R, Miakota AE. Craniopharyngioma associated with pituitary adenoma and chordoma of Blumenbach’s clivus. Zh Vopr Neirokhir Im N N Burdenko (6):52–54, 1981.

13.

Wheatley T, Clark JD, Stewart S. Craniopharyngioma with hyperprolactinaemia due to a prolactinoma. J Neurol Neurosurg Psychiatry 49(11):1305–7, 1986. doi:10.1136/jnnp.49.11.1305.PubMedCrossRef

14.

Horvath E, Kovacs K, Smyth HS, Killinger DW, Scheithauer BW, Randall R, Laws ER Jr, Singer W. A novel type of pituitary adenoma: morphological features and clinical correlations. J Clin Endocrinol and Metab 66(6):1111–8, 1988.

15.

Horvath E, Kovacs K, Smyth HS, Cusimano M, Singer W. Silent adenoma subtype 3 of the pituitary—immunohistochemical and ultrastructural classification: a review of 29 cases. Ultrastruct Pathol 29(6):511–24, 2005. doi:10.1080/01913120500323514.PubMedCrossRef

16.

Kontogeorgos G, Kovacs K, Horwath E, Scheithauer BW. Multiple adenomas of the human pituitary: a retrospective autopsy study with clinical implications. J Neurosurg 74(2):243–7, 1991.PubMedCrossRef

17.

Kontogeorgos G, Scheithauer BW, Horvath E, Kovacs K, Lloyd RV, Smyth HS, Rologis D. Double adenomas of the pituitary: a clinicopathological study of 11 tumors. Neurosurg 31(5):840–9, 1992. doi:10.1097/00006123-199211000-00003.CrossRef

18.

Kim K, Yamada S, Usui M, Sano T. Preoperative identification of clearly separated double pituitary adenomas. Clin Endocrinol (Oxf) 61(1):26–30, 2004. doi:10.1111/j.1365-2265.2004.02055.x.CrossRef

19.

Sano T, Horiguchi H, Xu B, Li C, Hino A, Sakaki M, Kannuki S, Yamada S. Double pituitary adenomas: six surgical cases. Pituitary 1(3–4):243–50, 1999. doi:10.1023/A:1009994123582.PubMedCrossRef

20.

McKelvie PA, McNeill P. Double pituitary adenomas: a series of three patients. Pathology 34(1):57–60, 2002.PubMedCrossRef

Titel: Collision Tumors of the Sella: Craniopharyngioma and Silent Pituitary Adenoma Subtype 3: Case Report
verfasst von: Olga Moshkin
Bernd W. Scheithauer
Luis V. Syro
Alejandro Velasquez
Eva Horvath
Kalman Kovacs
Publikationsdatum: 01.03.2009
Verlag: Humana Press Inc
Erschienen in: Endocrine Pathology / Ausgabe 1/2009
Print ISSN: 1046-3976
Elektronische ISSN: 1559-0097
DOI: https://doi.org/10.1007/s12022-009-9065-3

Die Highlights vom Kongress des American College of Cardiology 2024

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Collision Tumors of the Sella: Craniopharyngioma and Silent Pituitary Adenoma Subtype 3: Case Report

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

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