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Virchows Archiv
Erschienen in: Virchows Archiv 2/2017

27.05.2017 | Invited Annual Review Issue

Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm

verfasst von: Larissa V. Furtado, Wade S. Samowitz

Erschienen in: Virchows Archiv | Ausgabe 2/2017

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Abstract

Advances in defining the mutational landscape of colorectal cancer (CRC) over the past decades have revolutionized the molecular understanding and clinical testing algorithms for this disease. Mutation testing is standard of care for the work-up of CRCs. This review focuses on the current indications and strategies for molecular testing in CRC and discusses the potential changes in CRC testing approach associated with the emerging clinical application of genomic-based technologies.
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Metadaten
Titel
Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm
verfasst von
Larissa V. Furtado
Wade S. Samowitz
Publikationsdatum
27.05.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Virchows Archiv / Ausgabe 2/2017
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-017-2153-8

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