Erschienen in:
01.09.2020 | Original Article
Computed tomography findings of current nonspecific interstitial pneumonia based on the 2013 updated classification of idiopathic interstitial pneumonias: What is a characteristic of previously diagnosed nonspecific interstitial pneumonia excluded from the updated classification
verfasst von:
Junya Tominaga, Tae Iwasawa, Makiko Murota, Hiroaki Arakawa, Takeshi Johkoh, Yasuhiko Yamano, Yoshiaki Zaizen, Kazuya Ichikado, Mikiko Hashisako, Yasuhiro Kondoh, Kensuke Kataoka, Masaki Okamoto, Kiminori Fujimoto, Junya Fukuoka, on behalf of the Study Group of Creation of Radiological Paper from Japan in Diffuse Lung Disease
Erschienen in:
Japanese Journal of Radiology
|
Ausgabe 1/2021
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Abstract
Purpose
To evaluate computed tomography (CT) findings of nonspecific interstitial pneumonia (NSIP) based on the current classification of idiopathic interstitial pneumonias (IIPs) and elucidate a characteristic of previously diagnosed NSIP excluded from the current classification.
Materials and methods
The study included 74 patients with biopsy-proven NSIP (idiopathic NSIP [I-NSIP], 39 patients; NSIP associated with connective tissue disease [CTD-NSIP], 35 patients). Among patients who were compatible with the current classification of IIPs, 29 and 21 were categorized as having current I-NSIP and current CTD-NSIP, respectively. The remaining 24 patients were categorized as having previous I-NSIP or previous CTD-NSIP due to the primary pathologic diagnosis of cellular NSIP or associated findings of acute inflammatory changes. CT findings were evaluated and compared among the four groups.
Results
Current I-NSIP was indicated by ground-glass attenuation and reticulation with traction bronchiectasis/bronchiolectasis in predominantly peribronchovascular areas of the lower lung zone. The previous I-NSIP group tended to show broader airspace consolidation than the current I-NSIP group (p = 0.068). The previous CTD-NSIP group showed significantly broader airspace consolidation than the current I-NSIP group (p = 0.035).
Conclusion
Broad airspace consolidation is a characteristic of previously diagnosed CTD-NSIP excluded from the current classification of IIPs.