Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Japanese Journal of Radiology
Erschienen in: Japanese Journal of Radiology 8/2017

26.05.2017 | Original Article

Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification

verfasst von: Suguru Sato, Yosuke Horii, Norihiko Yoshimura, Takuya Yagi, Hidefumi Aoyama

Erschienen in: Japanese Journal of Radiology | Ausgabe 8/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To compare coronary computed tomography angiography (CTA) and coronary angiography (CAG) with regard to luminal graphic definition of calcified segments using 128-slice dual-source computed tomography (DSCT), specifically for patients with an Agatston score >400.

Materials and methods

Of 1148 consecutive patients who underwent coronary CTA using a 128-slice DSCT, 132 subjects had severe calcification with an Agatston score >400. Thirty-nine of the 132 patients who had undergone CAG within 3 months before or after coronary CTA were included. We investigated the distribution of calcification, and we visually evaluated significant stenosis in the calcified and all segments. Results were compared with CAG.

Results

The target group in this study had a very high mean Agatston score of 1771 ± 1724. Results for sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 247 calcified vs all 325 segments were as follows: sensitivity 93.2 vs 92.2%, specificity 83.9 vs 87.5%, PPV 70.8 vs 69.6%, and NPV 96.7 vs 97.3%, respectively.

Conclusion

128-slice DSCT has potential for evaluation of calcified segments in the lumen, even in patients whose Agatston score exceeds 400.
Literatur
1.
Hamon M, Biondi-Zoccai GG, Malagutti P, Agostoni P, Morello R, Valgimigli M, et al. Diagnostic performance of multislice spiral computed tomography of coronary arteries as compared with conventional invasive coronary angiography: a meta-analysis. J Am Coll Cardiol. 2006;48:1896–910.CrossRefPubMed
2.
Schroeder S, Achenbach S, Bengel F, Burgstahler C, Cademartiri F, de Feyter P, et al. Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a writing group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology. Eur Heart J. 2008;29:531–56.CrossRefPubMed
3.
Hoffmann U, Moselewski F, Cury RC, Ferencik M, Jang IK, Diaz LJ, et al. Predictive value of 16-slice multidetector spiral computed tomography to detect significant obstructive coronary artery disease in patients at high risk for coronary artery disease: patient- versus segment-based analysis. Circulation. 2004;110:2638–43.CrossRefPubMed
4.
Hoffmann U, Ferencik M, Cury RC, Pena AJ. Coronary CT angiography. J Nucl Med. 2006;47:797–806.PubMed
5.
Budoff MJ, Dowe D, Jollis JG, Gitter M, Sutherland J, Halamert E, et al. Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (assessment by coronary computed tomographic angiography of individuals undergoing invasive coronary angiography) trial. J Am Coll Cardiol. 2008;52:1724–32.CrossRefPubMed
6.
Taylor AJ, Cerqueira M, Hodgson JM, Mark D, Min J, O’Gara P, et al. ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance. J Am Coll Cardiol. 2010;56:1864–94.CrossRefPubMed
7.
Brodoefel H, Burgstahler C, Tsiflikas I, Reimann A, Schroeder S, Claussen CD, et al. Dual-source CT: effect of heart rate, heart rate variability, and calcification on image quality and diagnostic accuracy. Radiology. 2008;247:346–55.CrossRefPubMed
8.
Meng L, Cui L, Cheng Y, Wu X, Tang Y, Wang Y, et al. Effect of heart rate and coronary calcification on the diagnostic accuracy of the dual-source CT coronary angiography in patients with suspected coronary artery disease. Korean J Radiol. 2009;10:347–54.CrossRefPubMedPubMedCentral
9.
Achenbach S, Ropers D, Kuettner A, Flohr T, Ohnesorge B, Bruder H, et al. Contrast-enhanced coronary artery visualization by dual-source computed tomography—initial experience. Eur J Radiol. 2006;57:331–5.CrossRefPubMed
10.
Vavere AL, Arbab-Zadeh A, Rochitte CE, Dewey M, Niinuma H, Gottlieb I, et al. Coronary artery stenoses: accuracy of 64-detector row CT angiography in segments with mild, moderate, or severe calcification—a subanalysis of the CORE-64 trial. Radiology. 2011;261:100–1008.CrossRefPubMedPubMedCentral
11.
Ohashi K, Ichikawa K, Hara M, Kawai T, Kunitomo H, Higashide R, et al. Examination of the optimal temporal resolution required for computed tomography coronary angiography. Radiol Phys Technol. 2013;6:453–60.CrossRefPubMed
12.
Schuhbaeck A, Schmid J, Zimmer T, Muschiol G, Hell MM, Marwan M, et al. Influence of the coronary calcium score on the ability to rule out coronary artery stenoses by coronary CT angiography in patients with suspected coronary artery disease. J Cardiovasc Comput Tomogr. 2016;10:343–50.CrossRefPubMed
13.
Scheffel H, Alkadhi H, Plass A, Vachenauer R, Desbiolles L, Gaemperli O, et al. Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol. 2006;16:2739–47.CrossRefPubMedPubMedCentral
14.
Raff GL, Gallagher MJ, O’Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005;46:552–7.CrossRefPubMed
15.
Leschka S, Alkadhi H, Plass A, Desbiolles L, Grünenfelder J, Marincek B, et al. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J. 2005;26:1482–7.CrossRefPubMed
16.
Mollet NR, Cademartiri F, van Mieghem CA, Runza G, McFadden EP, Baks T, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation. 2005;112:2318–23.CrossRefPubMed
17.
Schuijf JD, Pundziute G, Jukema JW, Lamb HJ, van der Hoeven BL, de Roos A, van der Wall EE, et al. Diagnostic accuracy of 64-slice multislice computed tomography in the noninvasive evaluation of significant coronary artery disease. Am J Cardiol. 2006;98:145–8.CrossRefPubMed
18.
Ropers D, Rixe J, Anders K, Küttner A, Baum U, Bautz W, et al. Usefulness of multidetector row spiral computed tomography with 64- × 0.6-mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses. Am J Cardiol. 2006;97:343–8.CrossRefPubMed
19.
Vanhoenacker PK, Heijenbrok-Kal MH, Van Heste R, Decramer I, Van Hoe LR, Wijns W, et al. Diagnostic performance of multidetector CT angiography for assessment of coronary artery disease: meta-analysis. Radiology. 2007;244:419–28.CrossRefPubMed
20.
den Dekker MA, de Smet K, de Bock GH, Tio RA, Oudkerk M, Vliegenthart R. Diagnostic performance of coronary CT angiography for stenosis detection according to calcium score: systematic review and meta-analysis. Eur Radiol. 2012;22:2688–98.CrossRef
21.
Leber AW, Johnson T, Becker A, von Ziegler F, Tittus J, Nikolaou K, et al. Diagnostic accuracy of dual-source multi-slice CT-coronary angiography in patients with an intermediate pretest likelihood for coronary artery disease. Eur Heart J. 2007;28:2354–60.CrossRefPubMed
22.
Johnson TR, Nikolaou K, Busch S, Leber AW, Becker A, Wintersperger BJ, et al. Diagnostic accuracy of dual-source computed tomography in the diagnosis of coronary artery disease. Invest Radiol. 2007;42:684–91.CrossRefPubMed
23.
Ropers U, Ropers D, Pflederer T, Anders K, Kuettner A, Stilianakis NI, et al. Influence of heart rate on the diagnostic accuracy of dual-source computed tomography coronary angiography. J Am Coll Cardiol. 2007;50:2393–8.CrossRefPubMed
24.
Weustink AC, Meijboom WB, Mollet NR, Otsuka M, Pugliese F, van Mieghem C, et al. Reliable high-speed coronary computed tomography in symptomatic patients. J Am Coll Cardiol. 2007;50:786–94.CrossRefPubMed
25.
Alkadhi H, Scheffel H, Desbiolles L, Gaemperli O, Stolzmann P, Plass A, et al. Dual-source computed tomography coronary angiography: influence of obesity, calcium load, and heart rate on diagnostic accuracy. Eur Heart J. 2008;29:766–76.CrossRefPubMed
26.
Stolzmann P, Scheffel H, Leschka S, Plass A, Baumüller S, Marincek B, et al. Influence of calcifications on diagnostic accuracy of coronary CT angiography using prospective ECG triggering. AJR Am J Roentgenol. 2008;191:1684–9.CrossRefPubMed
27.
Lin CJ, Hsu JC, Lai YJ, Wang KL, Lee JY, Li AH, et al. Diagnostic accuracy of dual-source CT coronary angiography in a population unselected for degree of coronary artery calcification and without heart rate modification. Clin Radiol. 2010;65:109–17.CrossRefPubMed
28.
Tsiflikas I, Brodoefel H, Reimann AJ, Thomas C, Ketelsen D, Schroeder S, et al. Coronary CT angiography with dual source computed tomography in 170 patients. Eur J Radiol. 2010;74:161–5.CrossRefPubMed
29.
Singh S, Singh N, Gulati GS, Ramakrishnan S, Kumar G, Sharma S, et al. Dual-source computed tomography for chronic total occlusion of coronary arteries. Catheter Cardiovasc Interv. 2016;88:E117–25.CrossRefPubMed
Metadaten
Titel
Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification
verfasst von
Suguru Sato
Yosuke Horii
Norihiko Yoshimura
Takuya Yagi
Hidefumi Aoyama
Publikationsdatum
26.05.2017
Verlag
Springer Japan
Erschienen in
Japanese Journal of Radiology / Ausgabe 8/2017
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-017-0650-y

Weitere Artikel der Ausgabe 8/2017

Japanese Journal of Radiology 8/2017 Zur Ausgabe

Original Article

Comparison of lesion enhancement between BB Cube and 3D-SPGR images for brain tumors with 1.5-T magnetic resonance imaging

Original Article

Biliary stone removal through the percutaneous transhepatic biliary drainage route, focusing on the balloon sphincteroplasty flushing technique: a single center study with 916 patients

Original Article

Contrast-induced nephropathy (CIN) of patients with renal dysfunction in CT examination

Review

Magnetic resonance image guidance in external beam radiation therapy planning and delivery

Original Article

A predictive diagnostic model using multiparametric MRI for differentiating uterine carcinosarcoma from carcinoma of the uterine corpus

Original Article

Orbital malignant lesions in adults: multiparametric MR imaging

Neu im Fachgebiet Radiologie

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Wie toxische Männlichkeit der Gesundheit von Männern schadet

08.04.2024 Andrologie Nachrichten

Stark, erfolgreich, allzeit belastbar – das sind Erwartungen, die Jungen und Männer von der Gesellschaft spüren. Das kann sie „toxisch“ werden lassen – und letztlich sogar der Gesundheit schaden, mahnt Dr. Dirk Sander von der Deutschen Aidshilfe.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen
Bildnachweise