Introduction
Material and methods
Results
Patient | Isolates | |
---|---|---|
C. coyleae
| Accompanying species | |
Bacteriuria (cfu/ml) | ||
1 | 103 | None |
2 | 103 | |
3 | 104 | |
4 | 104 | |
5 | 104 | |
6 | 104 | |
7 | 104 | E. faecalis (103) |
8 | 104 | E. faecalis (103) |
9 | 104 | E. faecalis (105) |
10 | 103 | E. coli (102) |
11 | 104 | E. coli (104) |
Patient | Isolates | |
---|---|---|
C. coyleae
| Accompanying species | |
Bacteriuria (cfu/ml) | ||
1 | 102 * | None |
2 | 103 | |
3 | 103 | |
4 | 103 | |
5 | 104 | |
6 | 104 | |
7 | 104 | |
8 | 104 | |
9 | 104 | |
10 | 105 | |
11 | 105 | |
12 | 104 | |
13 | 104 | |
14 | 104 | |
15 | 103 | P. mirabilis (103) |
16 | 104 | E. faecalis (103) |
17 | 104 | E. faecalis (103) |
18 | 104 | S. epidermidis (104) |
19 | 104 | S. saprophyticus (104) |
20 | 104 | E. coli (105) |
21 | 104 | P. vulgaris (105) |
22 | 105 | S. hominis (104) |
23 | 103 (predominant) | E. coli (103) + C. albicans (104) |
24 | 105 | E. coli (103) |
25 | 103 | S. haemolyticus (103) |
26 | 103 | E. faecalis (104) |
27 | 104 | E. faecalis (104) |
28 | 105 | S. agalactiae (104) |
Patient | Urine sample | Isolates/bacteriuria (cfu/ml) |
---|---|---|
Female, 73 years, UTI | Middle stream urine | C. coyleae (104) E. coli (105) |
Nephrostomy | E. coli (102) | |
Female, 26 years, UTI susp. | Nephrostomy (pyonephrosis) | C. coyleae (103) P. mirabilis (103) S. epidermidis (103) Prevotella spp. (105) P. assacharolyticus (105) Lactobacillus spp. (105) |
Nephrostomy (sample obtained 3 days later) | P. mirabilis (105) |
Antibiotic susceptibility of C. coyleae isolates | |||||
---|---|---|---|---|---|
Benzylpenicillin | Ciprofloxacin | Gentamycin | Tetracycline | Vancomycin | |
Our study (n = 39) | 5.1% | 43.6% | 69.2% | 87.2% | 100% |
Fernandez et al. [2] (n = 12) | 8.3% | 83.3% | 100% | 100% | 100% |
Discussion
Literature | Clinical significance |
---|---|
Funke et al. (1997) [1] | Females with overactive bladder syndrome |
Verhelst et al. (2006) [9] | C. coyleae occurred in 0.2% of vaginal microflora samples of healthy women (with grade 1 of Gram stain vaginal smears) |
Turk et al. (2007) [10] | C. coyleae occurred in the semen of men with prostatitis with severe (> 1 million WBC/ml semen) and moderate (0.2–1 milion WBC/ml semen) inflammation as well as in semen from controls |
Pearce et al. (2014) [11] | C. coyleae was most frequently cultured from urine samples from women with urgency urinary incontinence (UUI) than healthy controls |
Yang (2015) [12] | Occurrence in vaginal microflora across gestation in pregnant women treated with placebo or probiotics |
Brubaker et al. (2016) [13] | The statistical association between UUI symptoms and C. coyleae was demonstrated |
Schwaderer et al. (2017) [14] | Urine from women with urinary tract stones |
Barberis et al. (2018) [5] | Total nephrectomy following C. coyleae UTI in 36-year-old woman with a history of chronic kidney failure under hemodialysis due to polycystic kidney disease, with several episodes of UTI |