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Erschienen in: Skeletal Radiology 4/2010

01.04.2010 | Scientific Article

CT and MRI findings of calcified spinal meningiomas: correlation with pathological findings

verfasst von: Ji Won Lee, In Sook Lee, Kyung-Un Choi, Young Hwan Lee, Jae Hyuck Yi, Jong Woon Song, Kyung Jin Suh, Hak Jin Kim

Erschienen in: Skeletal Radiology | Ausgabe 4/2010

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Abstract

Objective

This study was designed to present characteristic CT and MR findings of calcified spinal meningiomas that correlate with pathological findings and to assess the efficacy of CT for the detection of calcifications within a mass in comparison to MRI.

Materials and methods

Between 1998 and 2009, 10 out of 11 patients who had pathologically confirmed psammomatous meningiomas showed gross calcifications on CT images and were included in this study. On CT scans of the 10 patients, the distribution pattern, morphology and number of calcifications within masses were evaluated. MRI was performed in seven patients and signal intensities of masses were assessed. The pathological results analyzed semi-quantitatively were compared with the density or the size of calcifications within a mass as seen on a CT scan.

Results

Seven of 10 masses were located at the thoracic spine level. Eight masses had intradural locations. The other two masses had extradural locations. Four masses were completely calcified based on standard radiographs and CT. Symptoms duration, the size of the mass and size or number of calcifications within a mass had no correlation. The location, size, and distribution pattern of calcifications within masses were variable. On MR images, signal intensity of calcified tumor varied on all imaging sequences. All the masses enhanced after injection of intravenous contrast material.

Conclusion

A calcified meningioma should be first suggested when extradural or intradural masses located in the spine contain calcifications regardless of the size or pattern as depicted on CT, especially in the presence of enhancement as seen on MR images.
Literatur
1.
Zurück zum Zitat Calogero JA, Moossy J. Extradural spinal meningiomas. Report of four cases. J Neurosurg. 1972;37:442–7.CrossRefPubMed Calogero JA, Moossy J. Extradural spinal meningiomas. Report of four cases. J Neurosurg. 1972;37:442–7.CrossRefPubMed
3.
Zurück zum Zitat Solero CL, Fornari M, Giombini S, et al. Spinal meningiomas: review of 174 operated cases. Neurosurgery. 1989;25:153–60.CrossRefPubMed Solero CL, Fornari M, Giombini S, et al. Spinal meningiomas: review of 174 operated cases. Neurosurgery. 1989;25:153–60.CrossRefPubMed
4.
Zurück zum Zitat Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL. Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg. 1985;62:18–24.CrossRefPubMed Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL. Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg. 1985;62:18–24.CrossRefPubMed
5.
Zurück zum Zitat De Verdelhan O, Haegelen C, Carsin-Nicol B, et al. MR imaging features of spinal schwannomas and meningiomas. J Neuroradiol. 2005;32:42–9.CrossRefPubMed De Verdelhan O, Haegelen C, Carsin-Nicol B, et al. MR imaging features of spinal schwannomas and meningiomas. J Neuroradiol. 2005;32:42–9.CrossRefPubMed
6.
Zurück zum Zitat Doita M, Harada T, Nishida K, Marui T, Kurosaka M, Yoshiya S. Recurrent calcified spinal meningioma detected by plain radiograph. Spine. 2001;26:E249–52.CrossRefPubMed Doita M, Harada T, Nishida K, Marui T, Kurosaka M, Yoshiya S. Recurrent calcified spinal meningioma detected by plain radiograph. Spine. 2001;26:E249–52.CrossRefPubMed
7.
Zurück zum Zitat Bonstelle CT, Vines FS. Calcification in a cervical intraspinal neurilemmoma. Neuroradiology. 1976;10:231–3.CrossRefPubMed Bonstelle CT, Vines FS. Calcification in a cervical intraspinal neurilemmoma. Neuroradiology. 1976;10:231–3.CrossRefPubMed
8.
Zurück zum Zitat Dross PE, Raji MR. CT myelography of calcified thoracic neurilemmoma. AJNR Am J Neuroradiol. 1985;6:967–8.PubMed Dross PE, Raji MR. CT myelography of calcified thoracic neurilemmoma. AJNR Am J Neuroradiol. 1985;6:967–8.PubMed
9.
Zurück zum Zitat Schimmel DH, Newton TH. Calcification within a thoracic neurilemmoma. Neuroradiology. 1974;8:55–6.CrossRefPubMed Schimmel DH, Newton TH. Calcification within a thoracic neurilemmoma. Neuroradiology. 1974;8:55–6.CrossRefPubMed
10.
Zurück zum Zitat Lombardi G, Passerini A. Spinal cord tumors. Radiology. 1961;76:381–92.PubMed Lombardi G, Passerini A. Spinal cord tumors. Radiology. 1961;76:381–92.PubMed
11.
Zurück zum Zitat Bailey P, Bucy PC. Origin and nature of meningeal tumors. Am J Cancer. 1931;15:15–54. Bailey P, Bucy PC. Origin and nature of meningeal tumors. Am J Cancer. 1931;15:15–54.
12.
Zurück zum Zitat Sandalcioglu IE, Hunold A, Muller O, Bassiouni H, Stolke D, Asgari S. Spinal meningiomas: critical review of 131 surgically treated patients. Eur Spine J. 2008;17:1035–41.CrossRefPubMed Sandalcioglu IE, Hunold A, Muller O, Bassiouni H, Stolke D, Asgari S. Spinal meningiomas: critical review of 131 surgically treated patients. Eur Spine J. 2008;17:1035–41.CrossRefPubMed
13.
Zurück zum Zitat Pear BL, Boyd HR. Roentgenographically visible calcifications in spinal meningioma. AJR Am J Roentgenol. 1974;120:32–45. Pear BL, Boyd HR. Roentgenographically visible calcifications in spinal meningioma. AJR Am J Roentgenol. 1974;120:32–45.
14.
Zurück zum Zitat Nystrom SH, Nyholm M. The origin of the calcium deposits in psammoma bodies of human spinal meningiomas. Naturwissenschaften. 1966;53:703–4.CrossRefPubMed Nystrom SH, Nyholm M. The origin of the calcium deposits in psammoma bodies of human spinal meningiomas. Naturwissenschaften. 1966;53:703–4.CrossRefPubMed
15.
Zurück zum Zitat Camp JD, Adson AW, Shugrue JJ. Roentgenographic findings associated with tumors of spinal column, spinal cord and associated tissues. Am J Cancer. 1933;17:348–72. Camp JD, Adson AW, Shugrue JJ. Roentgenographic findings associated with tumors of spinal column, spinal cord and associated tissues. Am J Cancer. 1933;17:348–72.
16.
Zurück zum Zitat Roux FX, Nataf F, Pinaudeau M, Borne G, Devaux B, Meder JF. Intraspinal meningiomas: review of 54 cases with discussion of poor prognosis factors and modern therapeutic management. Surg Neurol. 1996;46:458–63. discussion 463–64.CrossRefPubMed Roux FX, Nataf F, Pinaudeau M, Borne G, Devaux B, Meder JF. Intraspinal meningiomas: review of 54 cases with discussion of poor prognosis factors and modern therapeutic management. Surg Neurol. 1996;46:458–63. discussion 463–64.CrossRefPubMed
17.
Zurück zum Zitat Freidberg SR. Removal of an ossified ventral thoracic meningioma. Case report. J Neurosurg. 1972;37:728–30.CrossRefPubMed Freidberg SR. Removal of an ossified ventral thoracic meningioma. Case report. J Neurosurg. 1972;37:728–30.CrossRefPubMed
18.
Zurück zum Zitat Schaller B. Spinal meningioma: relationship between histological subtypes and surgical outcome? J Neurooncol. 2005;75:157–61.CrossRefPubMed Schaller B. Spinal meningioma: relationship between histological subtypes and surgical outcome? J Neurooncol. 2005;75:157–61.CrossRefPubMed
19.
Zurück zum Zitat Philippon J, Bataini JP, Cornu P, et al. Recurrent meningioma. Neurochirurgie. 1986;32(Suppl 1):1–84.PubMed Philippon J, Bataini JP, Cornu P, et al. Recurrent meningioma. Neurochirurgie. 1986;32(Suppl 1):1–84.PubMed
20.
Zurück zum Zitat Gezen F, Kahraman S, Canakci Z, Beduk A. Review of 36 cases of spinal cord meningioma. Spine. 2000;25:727–31.CrossRefPubMed Gezen F, Kahraman S, Canakci Z, Beduk A. Review of 36 cases of spinal cord meningioma. Spine. 2000;25:727–31.CrossRefPubMed
21.
Zurück zum Zitat Holland BA, Kucharcyzk W, Brant-Zawadzki M, Norman D, Haas DK, Harper PS. MR imaging of calcified intracranial lesions. Radiology. 1985;157:353–6.PubMed Holland BA, Kucharcyzk W, Brant-Zawadzki M, Norman D, Haas DK, Harper PS. MR imaging of calcified intracranial lesions. Radiology. 1985;157:353–6.PubMed
22.
Zurück zum Zitat Oot RF, New PF, Pile-Spellman J, Rosen BR, Shoukimas GM, Davis KR. The detection of intracranial calcifications by MR. AJNR Am J Neuroradiol. 1986;7:801–9.PubMed Oot RF, New PF, Pile-Spellman J, Rosen BR, Shoukimas GM, Davis KR. The detection of intracranial calcifications by MR. AJNR Am J Neuroradiol. 1986;7:801–9.PubMed
23.
Zurück zum Zitat Tsuchiya K, Makita K, Furui S, Nitta K. MRI appearances of calcified regions within intracranial tumours. Neuroradiol. 1993;35:341–4.CrossRef Tsuchiya K, Makita K, Furui S, Nitta K. MRI appearances of calcified regions within intracranial tumours. Neuroradiol. 1993;35:341–4.CrossRef
24.
Zurück zum Zitat Yamada S, Kawai S, Yonezawa T, Masui K, Nishi N, Fujiwara K. Cervical extradural en-plaque meningioma. Neurol Med Chir. 2007;47:36–9.CrossRef Yamada S, Kawai S, Yonezawa T, Masui K, Nishi N, Fujiwara K. Cervical extradural en-plaque meningioma. Neurol Med Chir. 2007;47:36–9.CrossRef
25.
Zurück zum Zitat Gambardella G, Toscano S, Staropoli C, et al. Epidural spinal meningioma. Role of magnetic resonance in differential diagnosis. Acta Neurochir. 1990;107:70–3.CrossRef Gambardella G, Toscano S, Staropoli C, et al. Epidural spinal meningioma. Role of magnetic resonance in differential diagnosis. Acta Neurochir. 1990;107:70–3.CrossRef
26.
Zurück zum Zitat El Khamary SM, Alorainy IA. Case 100: spinal epidural meningioma. Radiology. 2006;241:614–7.CrossRefPubMed El Khamary SM, Alorainy IA. Case 100: spinal epidural meningioma. Radiology. 2006;241:614–7.CrossRefPubMed
28.
Zurück zum Zitat Hu HP, Huang QL. Signal intensity correlation of MRI with pathological findings in spinal neurinomas. Neuroradiology. 1992;34:98–102.CrossRefPubMed Hu HP, Huang QL. Signal intensity correlation of MRI with pathological findings in spinal neurinomas. Neuroradiology. 1992;34:98–102.CrossRefPubMed
29.
Zurück zum Zitat Emamian SA, Skriver EB, Henriksen L, Cortsen ME. Lumbar herniated disk mimicking neurinoma. Case report. Acta Radiol. 1993;34:127–9.CrossRefPubMed Emamian SA, Skriver EB, Henriksen L, Cortsen ME. Lumbar herniated disk mimicking neurinoma. Case report. Acta Radiol. 1993;34:127–9.CrossRefPubMed
30.
Zurück zum Zitat Ashkenazi E, Pomeranz S, Floman Y. Foraminal herniation of a lumbar disc mimicking neurinoma on CT and MR imaging. J Spinal Dis. 1997;10:448–50. Ashkenazi E, Pomeranz S, Floman Y. Foraminal herniation of a lumbar disc mimicking neurinoma on CT and MR imaging. J Spinal Dis. 1997;10:448–50.
31.
Zurück zum Zitat Lambiase RE, Levine SM, Terek RM, Wyman JJ. Long bone surface osteomas: imaging features that may help avoid unnecessary biopsies. AJR Am J Roentgenol. 1998;171:775–8.PubMed Lambiase RE, Levine SM, Terek RM, Wyman JJ. Long bone surface osteomas: imaging features that may help avoid unnecessary biopsies. AJR Am J Roentgenol. 1998;171:775–8.PubMed
Metadaten
Titel
CT and MRI findings of calcified spinal meningiomas: correlation with pathological findings
verfasst von
Ji Won Lee
In Sook Lee
Kyung-Un Choi
Young Hwan Lee
Jae Hyuck Yi
Jong Woon Song
Kyung Jin Suh
Hak Jin Kim
Publikationsdatum
01.04.2010
Verlag
Springer-Verlag
Erschienen in
Skeletal Radiology / Ausgabe 4/2010
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-009-0771-1

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