Skip to main content
Erschienen in: European Radiology 11/2020

04.06.2020 | Musculoskeletal

CT fluoroscopy-guided transforaminal and intra-articular facet steroid injections for the treatment of cervical radiculopathy: injectate distribution patterns and association with clinical outcome

verfasst von: Nathalie J. Bureau, Thomas P. Moser, Arnaud Gouvion, Anne-Sophie Julien

Erschienen in: European Radiology | Ausgabe 11/2020

Einloggen, um Zugang zu erhalten

Abstract

Objectives

To investigate injectate dispersal patterns and their association with therapeutic efficacy during a transforaminal (TFSI) or an intra-articular facet steroid injection (IFSI) to treat cervical radiculopathy.

Methods

This retrospective study examined the post-intervention cervical spine CT of 56 patients randomized to receive one CT fluoroscopy–guided IFSI (29 patients; 10 (34.5%) males; mean age 45.0 years; SD 8.8 years; range 26–61 years) or TFSI (27 patients; 13 (48.2%) males; mean age 51.1 years; SD 11.2 years; range 29–72 years) (December 2010 to August 2013). The presence of contrast within the intra-articular facet, juxta-articular facet, retrodural, epidural, and foraminal and extraforaminal spaces during IFSI, and within the extraforaminal, foraminal, and epidural spaces during TFSI was assessed. Descriptive data are presented as frequencies. The association between injectate dispersal patterns and therapeutic efficacy, 4-week post-intervention, was assessed with ANCOVA models.

Results

During IFSI, the injectate predominantly spread to the retrodural (62%; 18/29) or juxta-articular (21%; 6/29) space. During TFSI, the injectate predominantly spread to the extraforaminal/foraminal spaces (41%; 11/27) or to the extraforaminal/foraminal/epidural spaces (33%; 9/27). Injectate presence in the juxta-articular (p = .007) or extraforaminal (p < .001) space was a predictor of therapeutic efficacy but not in the foraminal (p = .54), epidural (p = .89), or retrodural (p = .75) space.

Conclusions

TFSI and IFSI led to preferential extraforaminal and retrodural injectate spread, respectively. Targeting the extraforaminal or juxta-articular facet space improved the clinical efficacy of steroid injections when treating cervical radiculopathy.

Key Points

• During intra-articular facet injection, the injectate spreads from the facet joint to the retrodural space and rarely reaches the epidural and/or foraminal spaces.
• Epidural spread of the injectate during an anterolateral transforaminal steroid injection is the least effective for pain relief in patients with cervical radiculopathy.
• Injection techniques targeting the extraforaminal or juxta-articular facet space are safer than transforaminal injections and effectively relieve pain in patients with cervical radiculopathy.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Carette S, Fehlings MG (2005) Clinical practice. Cervical radiculopathy. N Engl J Med 353(4):392–399CrossRef Carette S, Fehlings MG (2005) Clinical practice. Cervical radiculopathy. N Engl J Med 353(4):392–399CrossRef
2.
Zurück zum Zitat Heckmann JG, Lang CJ, Zobelein I, Laumer R, Druschky A, Neundorfer B (1999) Herniated cervical intervertebral discs with radiculopathy: an outcome study of conservatively or surgically treated patients. J Spinal Disord 12(5):396–401CrossRef Heckmann JG, Lang CJ, Zobelein I, Laumer R, Druschky A, Neundorfer B (1999) Herniated cervical intervertebral discs with radiculopathy: an outcome study of conservatively or surgically treated patients. J Spinal Disord 12(5):396–401CrossRef
3.
Zurück zum Zitat Saal JS, Saal JA, Yurth EF (1996) Nonoperative management of herniated cervical intervertebral disc with radiculopathy. Spine (Phila Pa 1976) 21(16):1877–1883 Saal JS, Saal JA, Yurth EF (1996) Nonoperative management of herniated cervical intervertebral disc with radiculopathy. Spine (Phila Pa 1976) 21(16):1877–1883
4.
Zurück zum Zitat Cyteval C, Thomas E, Decoux E et al (2004) Cervical radiculopathy: open study on percutaneous periradicular foraminal steroid infiltration performed under CT control in 30 patients. AJNR Am J Neuroradiol 25(3):441–445PubMed Cyteval C, Thomas E, Decoux E et al (2004) Cervical radiculopathy: open study on percutaneous periradicular foraminal steroid infiltration performed under CT control in 30 patients. AJNR Am J Neuroradiol 25(3):441–445PubMed
5.
Zurück zum Zitat Lasbleiz J, Siegfried D, Chales G, Marin F, Sighetti M, Duvauferrier R (2008) Evaluation of CT guided cervical epidural injections in patients with mechanical cervicobrachial neuralgia. J Radiol 89(3 Pt 1):317–323CrossRef Lasbleiz J, Siegfried D, Chales G, Marin F, Sighetti M, Duvauferrier R (2008) Evaluation of CT guided cervical epidural injections in patients with mechanical cervicobrachial neuralgia. J Radiol 89(3 Pt 1):317–323CrossRef
6.
Zurück zum Zitat Vallee JN, Feydy A, Carlier RY, Mutschler C, Mompoint D, Vallee CA (2001) Chronic cervical radiculopathy: lateral-approach periradicular corticosteroid injection. Radiology 218(3):886–892CrossRef Vallee JN, Feydy A, Carlier RY, Mutschler C, Mompoint D, Vallee CA (2001) Chronic cervical radiculopathy: lateral-approach periradicular corticosteroid injection. Radiology 218(3):886–892CrossRef
7.
Zurück zum Zitat Derby R, Lee SH, Kim BJ, Chen Y, Seo KS (2004) Complications following cervical epidural steroid injections by expert interventionalists in 2003. Pain Physician 7(4):445–449PubMed Derby R, Lee SH, Kim BJ, Chen Y, Seo KS (2004) Complications following cervical epidural steroid injections by expert interventionalists in 2003. Pain Physician 7(4):445–449PubMed
8.
Zurück zum Zitat Lee JW, Hwang SY, Lee GY, Lee E, Kang HS (2014) Fluoroscopic cervical paramidline interlaminar epidural steroid injections for cervical radiculopathy: effectiveness and outcome predictors. Skeletal Radiol 43(7):933–938CrossRef Lee JW, Hwang SY, Lee GY, Lee E, Kang HS (2014) Fluoroscopic cervical paramidline interlaminar epidural steroid injections for cervical radiculopathy: effectiveness and outcome predictors. Skeletal Radiol 43(7):933–938CrossRef
9.
Zurück zum Zitat Hoang JK, Massoglia DP, Apostol MA, Lascola CD, Eastwood JD, Kranz PG (2013) CT-guided cervical transforaminal steroid injections: where should the needle tip be located? AJNR Am J Neuroradiol 34(3):688–692CrossRef Hoang JK, Massoglia DP, Apostol MA, Lascola CD, Eastwood JD, Kranz PG (2013) CT-guided cervical transforaminal steroid injections: where should the needle tip be located? AJNR Am J Neuroradiol 34(3):688–692CrossRef
10.
Zurück zum Zitat Scanlon GC, Moeller-Bertram T, Romanowsky SM, Wallace MS (2007) Cervical transforaminal epidural steroid injections: more dangerous than we think? Spine (Phila Pa 1976) 32(11):1249–1256CrossRef Scanlon GC, Moeller-Bertram T, Romanowsky SM, Wallace MS (2007) Cervical transforaminal epidural steroid injections: more dangerous than we think? Spine (Phila Pa 1976) 32(11):1249–1256CrossRef
11.
Zurück zum Zitat Anderberg L, Annertz M, Persson L, Brandt L, Saveland H (2007) Transforaminal steroid injections for the treatment of cervical radiculopathy: a prospective and randomised study. Eur Spine J 16(3):321–328CrossRef Anderberg L, Annertz M, Persson L, Brandt L, Saveland H (2007) Transforaminal steroid injections for the treatment of cervical radiculopathy: a prospective and randomised study. Eur Spine J 16(3):321–328CrossRef
12.
Zurück zum Zitat Provenzano DA, Fanciullo G (2007) Cervical transforaminal epidural steroid injections: should we be performing them? Reg Anesth Pain Med 32(2):168 author reply 169-170PubMed Provenzano DA, Fanciullo G (2007) Cervical transforaminal epidural steroid injections: should we be performing them? Reg Anesth Pain Med 32(2):168 author reply 169-170PubMed
13.
Zurück zum Zitat Rathmell JP, Benzon HT (2004) Transforaminal injection of steroids: should we continue? Reg Anesth Pain Med 29(5):397–399PubMed Rathmell JP, Benzon HT (2004) Transforaminal injection of steroids: should we continue? Reg Anesth Pain Med 29(5):397–399PubMed
14.
Zurück zum Zitat Wolter T, Knoeller S, Berlis A, Hader C (2010) CT-guided cervical selective nerve root block with a dorsal approach. AJNR Am J Neuroradiol 31(10):1831–1836CrossRef Wolter T, Knoeller S, Berlis A, Hader C (2010) CT-guided cervical selective nerve root block with a dorsal approach. AJNR Am J Neuroradiol 31(10):1831–1836CrossRef
15.
Zurück zum Zitat Wald JT, Maus TP, Geske JR et al (2012) Safety and efficacy of CT-guided transforaminal cervical epidural steroid injections using a posterior approach. AJNR Am J Neuroradiol 33(3):415–419CrossRef Wald JT, Maus TP, Geske JR et al (2012) Safety and efficacy of CT-guided transforaminal cervical epidural steroid injections using a posterior approach. AJNR Am J Neuroradiol 33(3):415–419CrossRef
16.
Zurück zum Zitat Bensler S, Sutter R, Pfirrmann CW, Peterson CK (2015) Long term outcomes from CT-guided indirect cervical nerve root blocks and their relationship to the MRI findings--a prospective study. Eur Radiol 25(11):3405–3413CrossRef Bensler S, Sutter R, Pfirrmann CW, Peterson CK (2015) Long term outcomes from CT-guided indirect cervical nerve root blocks and their relationship to the MRI findings--a prospective study. Eur Radiol 25(11):3405–3413CrossRef
17.
Zurück zum Zitat Sutter R, Pfirrmann CW, Zanetti M, Hodler J, Peterson CK (2011) CT-guided cervical nerve root injections: comparing the immediate post-injection anesthetic-related effects of the transforaminal injection with a new indirect technique. Skeletal Radiol 40(12):1603–1608CrossRef Sutter R, Pfirrmann CW, Zanetti M, Hodler J, Peterson CK (2011) CT-guided cervical nerve root injections: comparing the immediate post-injection anesthetic-related effects of the transforaminal injection with a new indirect technique. Skeletal Radiol 40(12):1603–1608CrossRef
18.
Zurück zum Zitat Bise S, Pesquer L, Feldis M et al (2018) Comparison of three CT-guided epidural steroid injection approaches in 104 patients with cervical radicular pain: transforaminal anterolateral, posterolateral, and transfacet indirect. Skeletal Radiol 47(12):1625–1633CrossRef Bise S, Pesquer L, Feldis M et al (2018) Comparison of three CT-guided epidural steroid injection approaches in 104 patients with cervical radicular pain: transforaminal anterolateral, posterolateral, and transfacet indirect. Skeletal Radiol 47(12):1625–1633CrossRef
19.
Zurück zum Zitat Bureau NJ, Moser T, Dagher JH et al (2014) Transforaminal versus intra-articular facet corticosteroid injections for the treatment of cervical radiculopathy: a randomized, double-blind, controlled study. AJNR Am J Neuroradiol 35(8):1467–1474CrossRef Bureau NJ, Moser T, Dagher JH et al (2014) Transforaminal versus intra-articular facet corticosteroid injections for the treatment of cervical radiculopathy: a randomized, double-blind, controlled study. AJNR Am J Neuroradiol 35(8):1467–1474CrossRef
20.
Zurück zum Zitat Amrhein TJ, Bozdogan E, Vekaria S et al (2019) Cross-sectional CT assessment of the extent of injectate spread at CT fluoroscopy-guided cervical epidural interlaminar steroid injections. Radiology 292(3):723–729CrossRef Amrhein TJ, Bozdogan E, Vekaria S et al (2019) Cross-sectional CT assessment of the extent of injectate spread at CT fluoroscopy-guided cervical epidural interlaminar steroid injections. Radiology 292(3):723–729CrossRef
21.
Zurück zum Zitat Goldstein CL, Pashuck TD, Ingalls KL et al (2019) Dispersal pattern of injectate after cervical epidural steroid injection evaluated with magnetic resonance imaging. Global Spine J 9(4):393–397CrossRef Goldstein CL, Pashuck TD, Ingalls KL et al (2019) Dispersal pattern of injectate after cervical epidural steroid injection evaluated with magnetic resonance imaging. Global Spine J 9(4):393–397CrossRef
22.
Zurück zum Zitat Park CH, Lee SH (2014) Contrast dispersion pattern and efficacy of computed tomography-guided cervical transforaminal epidural steroid injection. Pain Physician 17(6):487–492PubMed Park CH, Lee SH (2014) Contrast dispersion pattern and efficacy of computed tomography-guided cervical transforaminal epidural steroid injection. Pain Physician 17(6):487–492PubMed
23.
Zurück zum Zitat Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16(4):494–502CrossRef Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16(4):494–502CrossRef
24.
Zurück zum Zitat Okada K (1981) Studies on the cervical facet joints using arthrography of the cervical facet joint (author’s transl). Nihon Seikeigeka Gakkai Zasshi 55(6):563–580PubMed Okada K (1981) Studies on the cervical facet joints using arthrography of the cervical facet joint (author’s transl). Nihon Seikeigeka Gakkai Zasshi 55(6):563–580PubMed
25.
Zurück zum Zitat Murthy NS, Maus TP, Aprill C (2011) The retrodural space of Okada. AJR Am J Roentgenol 196(6):W784–W789CrossRef Murthy NS, Maus TP, Aprill C (2011) The retrodural space of Okada. AJR Am J Roentgenol 196(6):W784–W789CrossRef
Metadaten
Titel
CT fluoroscopy-guided transforaminal and intra-articular facet steroid injections for the treatment of cervical radiculopathy: injectate distribution patterns and association with clinical outcome
verfasst von
Nathalie J. Bureau
Thomas P. Moser
Arnaud Gouvion
Anne-Sophie Julien
Publikationsdatum
04.06.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 11/2020
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-020-06974-8

Weitere Artikel der Ausgabe 11/2020

European Radiology 11/2020 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.