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European Radiology

Erschienen in:

27.09.2017 | Cardiac

CT myocardial perfusion imaging: ready for prime time?

verfasst von: Richard A. P. Takx, Csilla Celeng, U. Joseph Schoepf

Erschienen in: European Radiology | Ausgabe 3/2018

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Abstract

The detection of functional coronary artery stenosis with coronary CT angiography (CCTA) is suboptimal. Additional CT myocardial perfusion imaging (CT-MPI) may be helpful to identify patients with myocardial ischaemia in whom coronary revascularization therapy would be beneficial. CT-MPI adds incremental diagnostic and prognostic value over obstructive disease on CCTA. It allows for the quantitation of myocardial blood flow and calculation of coronary flow reserve and shows good correlation with ¹⁵O-H₂O positron emission tomography and invasive fractional flow reserve. In addition, patients prefer CCTA/CT-MPI over SPECT, MRI and invasive coronary angiography. CT-MPI is ready for clinical use for detecting myocardial ischaemia caused by obstructive disease. Nevertheless, the clinical utility of CT-MPI to identify ischaemia in patients with non-obstructive/microvascular disease still has to be established.

Key Points

• CT-MPI can improve the positive predictive value of CCTA for lesion-specific ischaemia.

• CT-MPI adds incremental prognostic value over CCTA for major adverse cardiac events.

• CT-MPI correlates with ¹⁵ O-H ₂ O PET.

• CT-MPI/CCTA shows high overall patient satisfaction.

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Titel: CT myocardial perfusion imaging: ready for prime time?
verfasst von: Richard A. P. Takx
Csilla Celeng
U. Joseph Schoepf
Publikationsdatum: 27.09.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 3/2018
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-017-5057-8

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