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Pediatric Nephrology
Erschienen in: Pediatric Nephrology 9/2011

01.09.2011 | Review

Current perspectives on congenital obstructive nephropathy

verfasst von: Susan E. Ingraham, Kirk M. McHugh

Erschienen in: Pediatric Nephrology | Ausgabe 9/2011

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Abstract

Congenital obstructive nephropathy is the leading cause of chronic renal disease in children. As a result, it represents a tremendous societal burden in terms of morbidity and mortality, as well as in health care expenses of caring for children with chronic kidney disease and end-stage renal disease. The various diagnostic, prognostic, and therapeutic challenges associated with congenital obstructive nephropathy highlight the importance of developing effective experimental models for studying this disease process. In this review, we define the clinical entity that is congenital obstructive nephropathy, outline the current standards of diagnosis and care, and discuss the utilization of current experimental models designed to help clarify some of the clinical conundrums associated with this important disease.
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Metadaten
Titel
Current perspectives on congenital obstructive nephropathy
verfasst von
Susan E. Ingraham
Kirk M. McHugh
Publikationsdatum
01.09.2011
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Nephrology / Ausgabe 9/2011
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-011-1799-8

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