Skip to main content
Erschienen in: Der Internist 5/2005

01.05.2005 | Schwerpunkt: Hypertonie

Die neuen Richtlinien zur Behandlung der Hypertonie

verfasst von: Prof. Dr. H. Haller

Erschienen in: Die Innere Medizin | Ausgabe 5/2005

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die Behandlung des Bluthochdrucks ist ein zentrales Element in der Prävention kardiovaskulärer Erkrankungen. Die neue Klassifikation der Hypertonie trägt dem engen Zusammenhang zwischen der Höhe des Blutdrucks und dem kardiovaskulären Risiko Rechnung und bezeichnet einen Blutdruck zwischen 140/90 mmHg und 130/80 mmHg als hochnormal, sodass stets ein Blutdruck <140/90 mmHg erzielt werden sollte. Die therapeutisch zu erreichenden Blutdruckwerte werden aber auch durch das Ausmaß bereits bestehender Endorganschäden bestimmt. Für Patienten mit Diabetes mellitus gelten 130/80 mmHg und für Patienten mit einer Nierenerkrankung und Proteinurie 125/75 mmHg als therapeutischer Zielblutdruck. Für die primäre Therapie werden die 5 Substanzgruppen Diuretika, β-Blocker, Kalziumantagonisten, ACE-Hemmer und Angiotensinrezeptorenblocker empfohlen. Neben der antihypertensiven Wirkung sind substanzspezifische Wirkungen für ACE-Hemmer und Angiotensinrezeptorenblocker beschrieben. Primär kann statt einer Monotherapie auch eine niedrig dosierte Kombinationstherapie sinnvoll sein.
Literatur
1.
Zurück zum Zitat Wolf-Maier K, Cooper RS, Kramer H et al. (2004) Hypertension treatment and control in five European countries, Canada, and the United States. Hypertension 43: 10–17 Wolf-Maier K, Cooper RS, Kramer H et al. (2004) Hypertension treatment and control in five European countries, Canada, and the United States. Hypertension 43: 10–17
2.
Zurück zum Zitat Guidelines Sub-Committee World Health Organization (1999) International Society of Hypertension guidelines for the management of hypertension. J Hypertens 17: 151–183 Guidelines Sub-Committee World Health Organization (1999) International Society of Hypertension guidelines for the management of hypertension. J Hypertens 17: 151–183
3.
Zurück zum Zitat European Society of Hypertension Guidelines Committee (2003) European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 21: 1011–1053 European Society of Hypertension Guidelines Committee (2003) European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 21: 1011–1053
4.
Zurück zum Zitat Lenfant C, Chobanian AV, Jones DW, Roccella EJ; Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (2003) Seventh report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7). Hypertension 41: 1178–1179 Lenfant C, Chobanian AV, Jones DW, Roccella EJ; Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (2003) Seventh report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7). Hypertension 41: 1178–1179
5.
Zurück zum Zitat Collins R, Peto R, MacMahon S et al.(1990) Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 335: 827–839 Collins R, Peto R, MacMahon S et al.(1990) Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 335: 827–839
6.
Zurück zum Zitat MacMahon S, Peto R, Cutler J et al. (1990) Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 335: 765–774 MacMahon S, Peto R, Cutler J et al. (1990) Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 335: 765–774
7.
Zurück zum Zitat Prospective Studies Collaboration (2002) Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360: 1903–1913 Prospective Studies Collaboration (2002) Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360: 1903–1913
8.
Zurück zum Zitat Kjeldsen SE, Julius S, Hedner T, Hansson L (2001) Stroke is more common than myocardial infarction in hypertension: analysis based on 11 major randomized intervention trials. Blood Press 10: 190–192 Kjeldsen SE, Julius S, Hedner T, Hansson L (2001) Stroke is more common than myocardial infarction in hypertension: analysis based on 11 major randomized intervention trials. Blood Press 10: 190–192
9.
Zurück zum Zitat Primatesta P, Brookes M, Poulter NR (2001) Improved hypertension management and control. Results from the Health Survey for England 1998. Hypertension 38: 827–832 Primatesta P, Brookes M, Poulter NR (2001) Improved hypertension management and control. Results from the Health Survey for England 1998. Hypertension 38: 827–832
10.
Zurück zum Zitat Franklin S, Khan SA, Wong DA, Larson MG, Levy D (1999) Is pulse pressure useful in predicting risk for coronary heart disease? The Framingham Heart Study. Circulation 100: 354–360 Franklin S, Khan SA, Wong DA, Larson MG, Levy D (1999) Is pulse pressure useful in predicting risk for coronary heart disease? The Framingham Heart Study. Circulation 100: 354–360
11.
Zurück zum Zitat Anderson KM, Wilson PW, Odell PM, Kannel WB (1991) An updated coronary risk profile. A statement for health professionals. Circulation 83: 356–362 Anderson KM, Wilson PW, Odell PM, Kannel WB (1991) An updated coronary risk profile. A statement for health professionals. Circulation 83: 356–362
12.
Zurück zum Zitat Conroy RM, Pyorala K, Fitzgerald AP et al. on behalf of the SCORE Project Group (2003) Prediction of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 24: 987–1003 Conroy RM, Pyorala K, Fitzgerald AP et al. on behalf of the SCORE Project Group (2003) Prediction of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 24: 987–1003
13.
Zurück zum Zitat Keil U, Liese AD, Hense HW, Filipiak B, Doring A, Stieber J, Lowel H (1998) Classical risk factors and their impact on incident non-fatal and fatal myocardial infarction and all-cause mortality in southern Germany. Results from the MONICA Augsburg cohort study 1984–1992. Monitoring Trends and Determinants in Cardiovascular Diseases. Eur Heart J 19: 1197–1207 Keil U, Liese AD, Hense HW, Filipiak B, Doring A, Stieber J, Lowel H (1998) Classical risk factors and their impact on incident non-fatal and fatal myocardial infarction and all-cause mortality in southern Germany. Results from the MONICA Augsburg cohort study 1984–1992. Monitoring Trends and Determinants in Cardiovascular Diseases. Eur Heart J 19: 1197–1207
14.
Zurück zum Zitat Ridker PM (2003) Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 107: 363–369 Ridker PM (2003) Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 107: 363–369
15.
Zurück zum Zitat O’Brien E, Waeber B, Parati G, Staessen J, Myers MG (2001) Blood pressure measuring devices: recommendations of the European Society of Hypertension. BMJ 322: 531–536 O’Brien E, Waeber B, Parati G, Staessen J, Myers MG (2001) Blood pressure measuring devices: recommendations of the European Society of Hypertension. BMJ 322: 531–536
16.
Zurück zum Zitat Mancia G, Parati G (2000) Ambulatory blood pressure monitoring and organ damage. Hypertension 36: 894–900 Mancia G, Parati G (2000) Ambulatory blood pressure monitoring and organ damage. Hypertension 36: 894–900
17.
Zurück zum Zitat Mancia G, Zanchetti A, Agabiti-Rosei E et al. (1997) Ambulatory blood pressure is superior to clinic blood pressure in predicting treatment induced regression of left ventricular hypertrophy. Circulation 95: 1464–1470 Mancia G, Zanchetti A, Agabiti-Rosei E et al. (1997) Ambulatory blood pressure is superior to clinic blood pressure in predicting treatment induced regression of left ventricular hypertrophy. Circulation 95: 1464–1470
18.
Zurück zum Zitat Staessen JA, Thijs L, Fagard R et al. (1999) Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. JAMA 282: 539–546 Staessen JA, Thijs L, Fagard R et al. (1999) Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. JAMA 282: 539–546
19.
Zurück zum Zitat Liu JE, Roman MJ, Pini R, Schwartz JE, Pickering TG, Devereux RB (1999) Cardiac and arterial target organ damage in adults with elevated ambulatory and normal office blood pressure. Ann Intern Med 131: 564–572 Liu JE, Roman MJ, Pini R, Schwartz JE, Pickering TG, Devereux RB (1999) Cardiac and arterial target organ damage in adults with elevated ambulatory and normal office blood pressure. Ann Intern Med 131: 564–572
20.
Zurück zum Zitat Cuspidi C, Ambrosioni E, Mancia G, Pessina AC, Trimarco B, Zanchetti A (2002) Role of echocardiography and carotid ultrasonography in stratifying risk in patients with essential hypertension: the Assessment of Prognostic Risk Observational Survey. J Hypertens 20: 1307–1314 Cuspidi C, Ambrosioni E, Mancia G, Pessina AC, Trimarco B, Zanchetti A (2002) Role of echocardiography and carotid ultrasonography in stratifying risk in patients with essential hypertension: the Assessment of Prognostic Risk Observational Survey. J Hypertens 20: 1307–1314
21.
Zurück zum Zitat Liao D, Cooper L, Cai J et al. (1996) Presence and severity of cerebral white matter lesions and hypertension, its treatment, and its control: The ARIC Study. Stroke 27: 2262–2270 Liao D, Cooper L, Cai J et al. (1996) Presence and severity of cerebral white matter lesions and hypertension, its treatment, and its control: The ARIC Study. Stroke 27: 2262–2270
22.
Zurück zum Zitat Skoog I, Lernfelt B, Landahl S et al. (1996) 15-year longitudinal study of blood pressure and dementia. Lancet 347: 1141–1145 Skoog I, Lernfelt B, Landahl S et al. (1996) 15-year longitudinal study of blood pressure and dementia. Lancet 347: 1141–1145
23.
Zurück zum Zitat Kilander L, Nyman H, Boberg M, Hansson L, Lithell H (1998) Hypertension is related to cognitive impairment: A 20-year follow-up of 999 men. Hypertension 31: 780–786 Kilander L, Nyman H, Boberg M, Hansson L, Lithell H (1998) Hypertension is related to cognitive impairment: A 20-year follow-up of 999 men. Hypertension 31: 780–786
24.
Zurück zum Zitat Krumme W, Blum U, Schwertfeger E, FlÜgel P, Höllstin F, Schollmeyer P, Rump LC (1996) Diagnosis of renovascular disease by intra- and extrarenal Doppler scanning. Kidney Int 50: 1288–1292 Krumme W, Blum U, Schwertfeger E, FlÜgel P, Höllstin F, Schollmeyer P, Rump LC (1996) Diagnosis of renovascular disease by intra- and extrarenal Doppler scanning. Kidney Int 50: 1288–1292
25.
Zurück zum Zitat PROGRESS Collaborative Study Group (2001) Randomised trial of perindopril based blood pressure-lowering regimen among 6108 individuals with previous stroke or transient ischaemic attack. Lancet 358: 1033–1041 PROGRESS Collaborative Study Group (2001) Randomised trial of perindopril based blood pressure-lowering regimen among 6108 individuals with previous stroke or transient ischaemic attack. Lancet 358: 1033–1041
26.
Zurück zum Zitat The Heart Outcomes Prevention Evaluation Study Investigators (2000) Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 342: 145–153 The Heart Outcomes Prevention Evaluation Study Investigators (2000) Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 342: 145–153
27.
Zurück zum Zitat Schrier RW, Estacio RO, Esler A, Mehler P (2002) Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and stroke. Kidney Int 61: 1086–1097 Schrier RW, Estacio RO, Esler A, Mehler P (2002) Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and stroke. Kidney Int 61: 1086–1097
28.
Zurück zum Zitat Vasan RS, Larson MG, Leip EP, Evans JC, O’Donnell CJ, Kannel WB, Levy D (2001) Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 345: 1291–1297 Vasan RS, Larson MG, Leip EP, Evans JC, O’Donnell CJ, Kannel WB, Levy D (2001) Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 345: 1291–1297
29.
Zurück zum Zitat Hansson L, Zanchetti A, Carruthers SG et al. (1998) Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 351: 1755–1762 Hansson L, Zanchetti A, Carruthers SG et al. (1998) Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 351: 1755–1762
30.
Zurück zum Zitat UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes. UKPDS38. BMJ 317: 703–713 UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes. UKPDS38. BMJ 317: 703–713
31.
Zurück zum Zitat Estacio RO, Jeffers BW, Hiatt WR, Biggerstaff SL, Gifford N, Schrier RW (1998) The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with non-insulin independent diabetes and hypertension. N Engl J Med 338: 645–652 Estacio RO, Jeffers BW, Hiatt WR, Biggerstaff SL, Gifford N, Schrier RW (1998) The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with non-insulin independent diabetes and hypertension. N Engl J Med 338: 645–652
32.
Zurück zum Zitat Heart Outcomes Prevention Evaluation (HOPE) Study investigators (2000) Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICROHOPE substudy. Lancet 355: 253–259 Heart Outcomes Prevention Evaluation (HOPE) Study investigators (2000) Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICROHOPE substudy. Lancet 355: 253–259
33.
Zurück zum Zitat Blood Pressure Lowering Treatment Trialists‘ Collaboration (2000) Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 356: 1955–1964 Blood Pressure Lowering Treatment Trialists‘ Collaboration (2000) Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 356: 1955–1964
34.
Zurück zum Zitat Gueyffier F, Boutitie F, Boissel JP et al. (1997) The effect of antihypertensive drug treatment on cardiovascular outcomes in women and men. Results from a meta-analysis of individual patient data in randomised controlled trials. Ann Intern Med 126: 761–767 Gueyffier F, Boutitie F, Boissel JP et al. (1997) The effect of antihypertensive drug treatment on cardiovascular outcomes in women and men. Results from a meta-analysis of individual patient data in randomised controlled trials. Ann Intern Med 126: 761–767
35.
Zurück zum Zitat Lithell H, Hansson L, Skogg I et al. for the SCOPE Study Group (2003) The Study on Cognition and Prognosis in the Elderly (SCOPE). Principal results of a randomised double-blind intervention trial. J Hypertens 21: 875–886 Lithell H, Hansson L, Skogg I et al. for the SCOPE Study Group (2003) The Study on Cognition and Prognosis in the Elderly (SCOPE). Principal results of a randomised double-blind intervention trial. J Hypertens 21: 875–886
36.
Zurück zum Zitat Brenner BM, Cooper ME, De Zeeuw D et al. (2001) Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 345: 861–869 Brenner BM, Cooper ME, De Zeeuw D et al. (2001) Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 345: 861–869
37.
Zurück zum Zitat Lewis EJ, Hunsicker LG, Clarke WR et al. (2001) Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 345: 851–860 Lewis EJ, Hunsicker LG, Clarke WR et al. (2001) Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 345: 851–860
38.
Zurück zum Zitat Parving HH, Lehnert H, Brochner-Mortensen J, Gomis R, Andersen S, Arner P (2001) The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 345: 870–878 Parving HH, Lehnert H, Brochner-Mortensen J, Gomis R, Andersen S, Arner P (2001) The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 345: 870–878
39.
Zurück zum Zitat Staessen JA, Wang J, Thijs L (2003) Cardiovascular prevention and blood pressure reduction: a qualitative overview updated until 1 March 2003. J Hypertens 21: 1055–1076 Staessen JA, Wang J, Thijs L (2003) Cardiovascular prevention and blood pressure reduction: a qualitative overview updated until 1 March 2003. J Hypertens 21: 1055–1076
40.
Zurück zum Zitat The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT). JAMA 288: 2981–2997 The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT). JAMA 288: 2981–2997
41.
Zurück zum Zitat Dahlöf B, Devereux RB, Kjeldsen SE et al. (2002) Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 359: 995–1003 Dahlöf B, Devereux RB, Kjeldsen SE et al. (2002) Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 359: 995–1003
42.
Zurück zum Zitat Zanchetti A, Hansson L, Menard J, Leonetti G, Rahn K, Warnold I, Wedel H (2001) Risk assessment and treatment benefit in intensively treated hypertensive patients of the Hypertension Optimal Treatment (HOT) study for the HOT Study Group. J Hypertens 19: 819–825 Zanchetti A, Hansson L, Menard J, Leonetti G, Rahn K, Warnold I, Wedel H (2001) Risk assessment and treatment benefit in intensively treated hypertensive patients of the Hypertension Optimal Treatment (HOT) study for the HOT Study Group. J Hypertens 19: 819–825
43.
Zurück zum Zitat Dinneen SF, Gerstein HC (1997) The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature. Arch Intern Med 157: 1413–1418 Dinneen SF, Gerstein HC (1997) The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature. Arch Intern Med 157: 1413–1418
44.
Zurück zum Zitat Thijs L, Fagard R, Lijnen P, Staessen J, Van Hoof R, Amery A (1992) A metaanalysis of outcome trials in elderly hypertensives. J Hypertens 10: 1103–1109 Thijs L, Fagard R, Lijnen P, Staessen J, Van Hoof R, Amery A (1992) A metaanalysis of outcome trials in elderly hypertensives. J Hypertens 10: 1103–1109
45.
Zurück zum Zitat Mogensen CE (1982) Long-term antihypertensive treatment inhibiting progression of diabetic nephropathy. BMJ 285: 685–688 Mogensen CE (1982) Long-term antihypertensive treatment inhibiting progression of diabetic nephropathy. BMJ 285: 685–688
Metadaten
Titel
Die neuen Richtlinien zur Behandlung der Hypertonie
verfasst von
Prof. Dr. H. Haller
Publikationsdatum
01.05.2005
Verlag
Springer-Verlag
Erschienen in
Die Innere Medizin / Ausgabe 5/2005
Print ISSN: 2731-7080
Elektronische ISSN: 2731-7099
DOI
https://doi.org/10.1007/s00108-005-1405-x

Weitere Artikel der Ausgabe 5/2005

Der Internist 5/2005 Zur Ausgabe

Weiterbildung · Zertifizierte Fortbildung

Diagnostik und Therapie des Schilddrüsenknotens

Mitteilungen des BDI

Mitteilungen BDI 5/05

Einführung zum Thema

Arterielle Hypertonie

Klinische Studien

PEACE-Studie

Schwerpunkt: Hypertonie

Blutdruck und Gehirn

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.