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Clinical Rheumatology

Erschienen in:

07.06.2016 | Original Article

Differences in cardiovascular manifestations between ankylosing spondylitis patients with and without kyphosis

verfasst von: Jun Fu, Manyan Wu, Yan Liang, Kai Song, Ming Ni, Yonggang Zhang, Jiying Chen

Erschienen in: Clinical Rheumatology | Ausgabe 8/2016

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Abstract

The objective of this study is to evaluate the differences in cardiovascular manifestations between ankylosing spondylitis (AS) patients with and without kyphosis. A retrospective review of consecutive AS patients treated at our hospital between June 2013 and June 2015 was performed. There were 122 patients who met all of the inclusion and exclusion criteria. Among these patients, there were 57 (ASK group) patients with global kyphosis (GK) > 40° and 65 (AS group) patients with GK < 40°. General information, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), electrocardiography, and echocardiography were record. ESR and CRP levels in the ASK group were significantly higher than the AS group (P < 0.05). Fifteen patients in ASK group but 3 patients in AS group suffered from a left ventricular high voltage (P < 0.05). Heart rate in ASK group was 83.91 ± 13.68 beats/min, and it was 73.88 ± 13.04 beats/min in AS group (P < 0.05). The E/A ratio was 1.13 ± 0.38 in ASK group and 1.32 ± 0.49 in AS group (P < 0.05). The mitral E-wave deceleration time and isovolumetric relaxation time were, respectively, 236.25 ± 34.26 ms and 101.86 ± 17.57 ms in ASK group, which were shorter in AS group (P < 0.05). This study showed that AS patients with kyphosis had a statistically increased incidence of cardiovascular complications including a more rapid heart rate, left ventricular high voltage, and left ventricular diastolic dysfunction.

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Titel: Differences in cardiovascular manifestations between ankylosing spondylitis patients with and without kyphosis
verfasst von: Jun Fu
Manyan Wu
Yan Liang
Kai Song
Ming Ni
Yonggang Zhang
Jiying Chen
Publikationsdatum: 07.06.2016
Verlag: Springer London
Erschienen in: Clinical Rheumatology / Ausgabe 8/2016
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-016-3324-8

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