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01.05.2014 | Interventional

Effectiveness of combined use of imprint cytological and histological examination in CT-guided tissue-core biopsy

verfasst von: Takuji Yamagami, Rika Yoshimatsu, Kenji Kajiwara, Masaki Ishikawa, Tomohiro Matsumoto, Hideaki Kakizawa, Naoyuki Toyoda, Terumitsu Hasebe, Kazuo Awai

Erschienen in: European Radiology | Ausgabe 5/2014

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Abstract

Objectives

This study evaluated the efficacy of the combination of imprint cytology and histology in tissue-core percutaneous biopsy under real-time computed tomography (CT) fluoroscopic guidance.

Methods

Between October 2009 and June 2013, 156 percutaneous needle biopsies were performed in our institution. Those obtained by tissue-core biopsy underwent both imprint cytological and histological examinations routinely after touch imprint cytology was performed on site to evaluate the samples’ sufficiency for cytological and pathological examination. Final diagnosis was confirmed by independent surgical pathology, independent culture results or clinical follow-up.

Results

Rates of adequate specimens and precise diagnosis, by combined cytological and histological examination were 100 % (156/156) and 96.2 % (150/156), by cytology 94.4 % (152/156) and 83.3 % (130/156) and by histology 99.3 % (155/156) and 92.3 % (144/156). Precise diagnosis was achieved by combined examinations in 94.7 % (89/94) of thoracic lesions, 97.6 % (40/41) of musculoskeletal lesions, and 100 % (21/21) of abdominal, pelvic and retroperitoneal lesions. In all 104 lesions diagnosed as malignant by CT-guided biopsy and in 30 of 52 diagnosed as benign, specific cell types could be proved by combined examinations.

Conclusions

Combined imprint cytology and histology performed after on-site touch imprint cytological evaluation improved the diagnostic ability of CT fluoroscopically guided biopsy.

Key points

• CT-guided needle biopsy is a well-established diagnostic technique.

• Touch imprint cytological evaluation on site is helpful in improving quality of CT-guided biopsy.

• The rate of diagnosing malignant lymphoma specifically with cytological examination is relatively low.

• The rate of specific diagnosis of benign lesion in musculoskeletal regions is low.

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Titel: Effectiveness of combined use of imprint cytological and histological examination in CT-guided tissue-core biopsy
verfasst von: Takuji Yamagami
Rika Yoshimatsu
Kenji Kajiwara
Masaki Ishikawa
Tomohiro Matsumoto
Hideaki Kakizawa
Naoyuki Toyoda
Terumitsu Hasebe
Kazuo Awai
Publikationsdatum: 01.05.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 5/2014
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-014-3104-2

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Effectiveness of combined use of imprint cytological and histological examination in CT-guided tissue-core biopsy