Erschienen in:
Open Access
01.12.2015 | Poster presentation
Endocan can be a predictive marker of severity of sepsis but cannot be a marker of acute respiratory distress syndrome in ICU patients
verfasst von:
M Mizunuma, H Ishikura, Y Nakamura, K Muranishi, S Morimoto, H Kaneyama, Y Izutani, T Nishida, A Murai
Erschienen in:
Critical Care
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Sonderheft 1/2015
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Excerpt
Endocan (endothelial cell specific molecule-1), a 50 kDa dermatan sulfate proteoglycan, is expressed by endothelial cells in the lung and kidney. It was reported that the serum Endocan level is related to the severity of sepsis and positive correlation with the mortality rate. On the other hand, it was also reported that lower levels of serum Endocan are associated with subsequent development of chronic kidney disease, and chronic liver disease acute lung injury (ALI) in trauma patients. The aim of this study is confirmation of the relationship between serum Endocan level and the severity of sepsis, and also the severity of acute respiratory distress syndrome (ARDS) in septic patients. …