Erschienen in:
01.08.2011 | SSAT/SAGES Joint Symposium
Endoscopic Mucosal Resection of Barrett’s Esophagus and Early Esophageal Cancer
verfasst von:
Jeffrey H. Peters, Thomas A. Watson
Erschienen in:
Journal of Gastrointestinal Surgery
|
Ausgabe 8/2011
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Excerpt
The introduction of endoscopic techniques capable of removing 2- to 3-cm pieces of mucosa and submucosa has been one of the most significant advances in the treatment of esophageal and gastric neoplasia over the past decade. Endoscopic mucosal resection (EMR) was initially developed in Japan by Inoue and others for treatment of superficial squamous cell carcinomas of the esophagus.
1 It was adopted slowly in the USA and Europe, and its use continues to evolve. The most common application in Western populations is for excisional biopsy of small (less than 2 cm) mucosal irregularities or nodules in patients with Barrett’s esophagus (BE), high-grade dysplasia (HGD), and intramucosal adenocarcinoma. Data to date support endoscopic resection (ER) as the treatment of choice for focal mucosal esophageal adenocarcinoma and as an important adjunct to radiofrequency (RF) ablation in dysplastic Barrett’s epithelium. …