nach oben

Neuropsychology Review

Erschienen in:

01.06.2015 | Review

Executive Functioning in Children and Adolescents Prenatally Exposed to Alcohol: A Meta-Analytic Review

verfasst von: Jennifer E. Khoury, Karen Milligan, Todd A. Girard

Erschienen in: Neuropsychology Review | Ausgabe 2/2015

Einloggen, um Zugang zu erhalten

Abstract

Prenatal alcohol exposure is associated with a constellation of adverse physical, neurocognitive and behavior outcomes, which comprise a continuum of disorders labeled Fetal Alcohol Spectrum Disorders (FASD). Extant research has consistently identified executive functions (EF) as a central impairment associated with FASD. Despite this, heterogeneity exists regarding the strength of the association between FASD and different EF, and this association has not yet been quantitatively synthesized. The current meta-analysis reviews 46 studies that compare children and adolescents with FASD to participants without FASD, on a variety of EF measures. In accordance with Miyake et al. Cognitive Psychology, 41, 49–100 (2000) three-factor model of EF, findings for the primary EF domains of working memory, inhibition, and set shifting are reviewed. Results indicate that children and adolescents with FASD demonstrate significant deficits across these EF, although the magnitude of effects diverged between EF, with working memory and inhibition yielding medium effects and set shifting yielding large effects. These results were moderated by sample characteristics, type of FASD diagnosis, and EF methodology. This quantitative synthesis offers novel future research directions.

In order to limit violations of the assumption of independent samples, effect sizes were averaged for separate FASD groups in the first and second stages of analyses. Effect sizes were computed separately for different FASD groups within a single study in the final stage of analysis (i.e., when examining diagnosis-related moderators).

Abel, E. L., & Hannigan, J. H. (1995). Maternal risk factors in fetal alcohol syndrome: provocative and permissive influences. Neurotoxicology and Teratology, 17, 445–462.PubMed

*Aragon, A. S., Kalberg, W. O., Buckley, D., Barela-Scott, L. M., Tabachnick, B. G., & May, P. A. (2008). Neuropsychological study of FASD in a sample of American Indian children: processing simple versus complex information. Alcoholism: Clinical and Experimental Research, 32, 2136–2148. doi:10.1111/j.1530-0277.2008.00802.x.

Ardila, A., Pineda, D., & Rosselli, M. (2000). Correlation between intelligence test scores and executive function measures. Archives of Clinical Neuropsychology, 15, 31–36. doi:10.1016/S0887-6177(98)00159-0.PubMed

Arffa, S. (2007). The relationship of intelligence to executive function and non-executive function measures in a sample of average, above average, and gifted youth. Archives of Clinical Neuropsychology, 22(8), 969–978. doi:10.1016/j.acn.2007.08.001.PubMed

Aronson, M., Hagberg, B., & Gillberg, C. (1997). Attention deficits and autistic spectrum problems in children exposed to alcohol during gestation: a follow‐up study. Developmental Medicine and Child Neurology, 39, 583–587. doi:10.1111/j.1469-8749.1997.tb07493.x.PubMed

*Astley, S. J., Aylward, E. H., Olson, H. C., Kerns, K., Brooks, A., Coggins, T. E., & Richards, T. (2009). Functional magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders. Journal of Neurodevelopmental Disorders, 1, 61–80. doi:10.1007/s11689-009-9004-0.PubMedCentralPubMed

Bailey, B. N., Delaney-Black, V., Covington, C. Y., Ager, J., Janisse, J., Hannigan, J. H., & Sokol, R. J. (2004). Prenatal exposure to binge drinking and cognitive and behavioral outcomes at age 7 years. American Journal of Obstetrics and Gynecology, 19, 1037–1043. doi:10.1016/j.ajog.2004.05.048.

Best, J. R., & Miller, P. H. (2010). A developmental perspective on executive function. Child Development, 81, 1641–1660. doi:10.1111/j.1467-8624.2010.01499.x.PubMedCentralPubMed

Beveridge, M., Jarrold, C., & Pettit, E. (2002). An experimental approach to executive fingerprinting in young children. Infant and Child Development, 11, 107–123. doi:10.1002/icd.300.

Bissonette, G. B., Powell, E. M., & Roesch, M. R. (2013). Neural structures underlying set-shifting: roles of medial prefrontal cortex and anterior cingulate cortex. Behavioural Brain Research, 250, 91–101. doi:10.1016/j.bbr.2013.04.037.

Boone, K. B., Ghaffarian, S., Lesser, I. M., & Hill-Gutierrez, E. (1993). Wisconsin card sorting test performance in healthy, older adults: relationship to age, sex, education, and IQ. Journal of Clinical Psychology, 49, 54–60. doi:10.1002/1097-4679(199301)49:1<54::AID-JCLP2270490108>3.0.CO;2-6.PubMed

Borenstein, M., Rothstein, D., & Cohen, J. (2005). Comprehensive meta- analysis: A computer program for research synthesis (version 2.0) [computer software]. Englewood: Biostat.

Borenstein, M., Hedges, L., Higgins, J., & Rothstein, H. (2009). Introduction to meta-analysis. Chichester: Wiley.

Boseck, J.J. (2013). Neuropsychological and adaptive skills deficits in children with attention-deficit/hyperactivity disorder with and without comorbid fetal alcohol spectrum disorder. Proquest Dissertations and Theses.

*Burden, M. J., Andrew, C., Saint‐Amour, D., Meintjes, E. M., Molteno, C. D., Hoyme, H. E., & Jacobson, S. W. (2009). The effects of fetal alcohol syndrome on response execution and inhibition: an event‐related potential study. Alcoholism: Clinical and Experimental Research, 33, 1994–2004. doi:10.1111/j.1530-0277.2009.01038.x.

*Burden, M. J., Westerlund, A., Muckle, G., Dodge, N., Dewailly, E., Nelson, C. A., & Jacobson, J. L. (2011). The effects of maternal binge drinking during pregnancy on neural correlates of response inhibition and memory in childhood. Alcoholism: Clinical and Experimental Research, 35, 69–82. doi:10.1111/j.1530-0277.2010.01323.x.

Buss, C., Entringer, S., Davis, E. P., Hobel, C. J., Swanson, J. M., Wadhwa, P. D., & Sandman, C. A. (2012). Impaired executive function mediates the association between maternal pre-pregnancy body mass index and child ADHD symptoms. PLoS One, 7, 1–8. doi:10.1371/journal.pone.0037758

Cepeda, N. J., Kramer, A. F., & Gonzalez de Sather, J. C. M. (2001). Changes in executive control across the life span: examination of task-switching performance. Developmental Psychology, 37, 715–730. doi:10.1037/0012-1649.37.5.715.PubMed

Chasnoff, I. J., Wells, A. M., Telford, E., Schmidt, C., & Messer, G. (2010). Neurodevelopmental functioning in children with FAS, pFAS, and ARND. Journal of Developmental and Behavioral Pediatrics, 31, 192–201. doi:10.1097/DBP.0b013e3181d5a4e2.PubMed

Cohen, J. (1988). A power primer. Psychological Bulletin, 112, 155–159. doi:10.1037/0033-2909.112.1.155.

*Coles, C. D., Platzman, K. A., Raskind‐Hood, C. L., Brown, R. T., Falek, A., & Smith, I. E. (1997). A comparison of children affected by prenatal alcohol exposure and attention deficit, hyperactivity disorder. Alcoholism: Clinical and Experimental Research, 21, 150–161. doi:10.1111/j.1530-0277.1997.tb03743.x.

Cone-Wesson, B. (2005). Prenatal alcohol and cocaine exposure: influences on cognition, speech, language, and hearing. Journal of Communication Disorders, 38, 279–302. doi:10.1016/j.jcomdis.2005.02.004.PubMed

Cooper, H., & Hedges, L. (Eds.). (1994). The handbook of research synthesis. New York: Russell Sage.

Corbett, B. A., Constantine, L. J., Hendren, R., Rocke, D., & Ozonoff, S. (2009). Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Research, 166, 210–222. doi:10.1016/j.psychres.2008.02.005.PubMedCentralPubMed

Dennis, M., Francis, D. J., Cirino, P. T., Schachar, R., Barnes, M. A., & Fletcher, J. M. (2009). Why IQ is not a covariate in cognitive studies of neurodevelopmental disorders. Journal of the International Neuropsychological Society, 15, 331–343.PubMedCentralPubMed

Disney, E. R., Iacono, W., McGue, M., Tully, E., & Legrand, L. (2008). Strengthening the case: prenatal alcohol exposure is associated with increased risk for conduct disorder. Pediatrics, 122, e1225–e1230. doi:10.1542/peds.2008-1380.PubMedCentralPubMed

*Diwadkar, V. A., Meintjes, E. M., Goradia, D., Dodge, N. C., Warton, C., Molteno, C. D., & Jacobson, J. L. (2013). Differences in cortico‐striatal‐cerebellar activation during working memory in syndromal and nonsyndromal children with prenatal alcohol exposure. Human Brain Mapping, 34, 1931–1945. doi:10.1002/hbm.22042.PubMed

D’Onofrio, B. M., Van Hulle, C. A., Waldman, I. D., Rodgers, J. L., Rathouz, P. J., & Lahey, B. B. (2007). Causal inferences regarding prenatal alcohol exposure and childhood externalizing problems. Archives of General Psychiatry, 64, 1296–1304. doi:10.1001/archpsyc.64.11.1296.PubMed

Duval, S., & Tweedie, R. (2000). Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 56, 455–463. doi:10.1111/j.0006-341X.2000.00455.x

Flak, A. L., Su, S., Bertrand, J., Denny, C. H., Kesmodel, U. S., & Cogswell, M. E. (2014). The association of mild, moderate, and binge prenatal alcohol exposure and child neuropsychological outcomes: a meta‐analysis. Alcoholism: Clinical and Experimental Research, 38, 214–226. doi:10.1111/acer.12214.

Friedman, N. P., & Miyake, A. (2004). The relations among inhibition and interference control functions: a latent-variable analysis. Journal of Experimental Psychology: General, 133, 101–135. doi:10.1037/0096-3445.133.1.10

Fryer, S.L. (2009). Characterization of BOLD response patterns during inhibitory control in individuals with prenatal alcohol exposure. Proquest Dissertations and Abstracts.

*Fryer, S. L., Mattson, S. N., Jernigan, T. L., Archibald, S. L., Jones, K. L., & Riley, E. P. (2012). Caudate volume predicts neurocognitive performance in youth with heavy prenatal alcohol exposure. Alcoholism: Clinical and Experimental Research, 36, 1932-1941. doi:10.1111/j.1530-0277.2012.01811.

*Fryer, S. L., McGee, C. L., Matt, G. E., Riley, E. P., & Mattson, S. N. (2007). Evaluation of psychopathological conditions in children with heavy prenatal alcohol exposure. Pediatrics, 119, e733–e741. doi:10.1542/peds.2006-1606.PubMed

Gathercole, S. E., Pickering, S. J., Knight, C., & Stegmann, Z. (2004). Working memory skills and educational attainment: evidence from national curriculum assessments at 7 and 14 years of age. Applied Cognitive Psychology, 18, 1–16. doi:10.1002/acp.934.

Gautam, P., Nuñez, S. C., Narr, K. L., Kan, E. C., & Sowell, E. R. (2014). Effects of prenatal alcohol exposure on the development of white matter volume and change in executive function. NeuroImage: Clinical, 5, 19–27. doi:10.1016/j.nicl.2014.05.010.

*Glass, L., Ware, A. L., Crocker, N., Deweese, B. N., Coles, C. D., Kable, J. A., & Mattson, S. N. (2013). Neuropsychological deficits associated with heavy prenatal alcohol exposure are not exacerbated by ADHD. Neuropsychology, 27, 713–726. doi:10.1037/a0033994.PubMedCentralPubMed

*Green, C. R., Mihic, A. M., Nikkel, S. M., Stade, B. C., Rasmussen, C., Munoz, D. P., & Reynolds, J. N. (2009). Executive function deficits in children with fetal alcohol spectrum disorders (FASD) measured using the Cambridge neuropsychological tests automated battery (CANTAB). Journal of Child Psychology and Psychiatry, 50, 688–697. doi:10.1111/j.1469-7610.2008.01990.x.PubMed

Guerri, C., Bazinet, A., & Riley, E. P. (2009). Foetal alcohol spectrum disorders and alterations in brain and behaviour. Alcohol and Alcoholism, 44, 108–114. doi:10.1093/alcalc/agn105.PubMedCentralPubMed

Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (1993). Wisconsin card sort test manual: Revised and expanded. Odessa: Psychological Assessment Resources.

Hedges, L. V., & Olkin, I. (1985). Statistical methods for meta-analysis. San Diego: Academic Press.

Hoyme, H. E., May, P. A., Kalberg, W. O., Kodituwakku, P., Gossage, J. P., Trujillo, P. M., & Robinson, L. K. (2005). A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria. Pediatrics, 115, 39–47. doi:10.1542/peds.2004-0259.PubMed

Huizinga, M., Dolan, C. V., & van der Molen, M. W. (2006). Age-related change in executive function: developmental trends and a latent variable analysis. Neuropsychologia, 44, 2017–2036. doi:10.1016/j.neuropsychologia.2006.01.010.PubMed

Kamigaki, T., Fukushima, T., Tamura, K., & Miyashita, Y. (2012). Neurodynamics of cognitive set shifting in monkey frontal cortex and its causal impact on behavioral flexibility. Journal of Cognitive Neuroscience, 24, 2171–2185. doi:10.1162/jocn_a_00277.PubMed

Kawashima, R., Satoh, K., Itoh, H., Ono, S., Furumoto, S., Gotoh, R., Koyama, M., Yoshioka, S., Takahashi, T., Takahashi, K., Yanagisawa, T., & Fukuda, H. (1996). Functional anatomy of GO/NO-GO discrimination and response selection - a PET study in man. Brain Research, 728, 79–89.

Klenberg, L., Korkman, M., & Lahti Nuuttila, P. (2001). Differential development of attention and executive functions in 3- to 12-year-old Finnish children. Developmental Neuropsychology, 20, 407–428. doi:10.1207/S15326942DN2001_6.PubMed

Kodituwakku, P. W. (2007). Defining the behavioral phenotype in children with fetal alcohol spectrum disorders: a review. Neuroscience & Biobehavioral Reviews, 31, 192–201. doi:10.1016/j.neubiorev.2006.06.020.

Kodituwakku, P., & Kodituwakku, E. (2014). Cognitive and behavioral profiles of children with fetal alcohol spectrum disorders. Current Developmental Disorders Reports, 1, 149–160. doi:10.1007/s40474-014-0022-6.

*Kodituwakku, P. W., Handmaker, N. S., Cutler, S. K., Weathersby, E. K., & Handmaker, S. D. (1995). Specific impairments in self- regulation in children exposed to alcohol prenatally. Alcoholism: Clinical and Experimental Research, 19, 1558–1564. doi:10.1111/j.1530-0277.1995.tb01024.x.

*Kodituwakku, P. W., May, P. A., Clericuzio, C. L., & Weers, D. (2001b). Emotion-related learning in individuals prenatally exposed to alcohol: an investigation of the relation between set shifting, extinction of responses, and behavior. Neuropsychologia, 39, 699–708. doi:10.1016/S0028-3932(01)00002-1.PubMed

*Kooistra, L., Crawford, S., Gibbard, B., Ramage, B., & Kaplan, B. J. (2010). Differentiating attention deficits in children with fetal alcohol spectrum disorder or attention‐deficit–hyperactivity disorder. Developmental Medicine and Child Neurology, 52, 205–211. doi:10.1111/j.1469-8749.2009.03352.x.PubMed

*Kooistra, L., Crawford, S., Gibbard, B., Kaplan, B. J., & Fan, J. (2011). Comparing attentional networks in fetal alcohol spectrum disorder and the inattentive and combined subtypes of attention deficit hyperactivity disorder. Developmental Neuropsychology, 36, 566–577. doi:10.1080/87565641.2010.549978.PubMed

*Korkman, M., Autti-Rämö, I., Koivulehto, H., & Granström, M. L. (1998). Neuropsychological effects at early school age of fetal alcohol exposure of varying duration. Child Neuropsychology, 4, 199–212. doi:10.1076/chin.4.3.199.3171.

Kray, J., Eber, J., & Lindenberger, U. (2004). Age differences in executive functioning across the lifespan: The role of verbalization in task preparation. Acta Psychologica, 115, 143–165. doi:10.1016/j.actpsy.2003.12.001.PubMed

Kyte, Z. A., Goodyer, I. M., & Sahakian, B. J. (2005). Selected executive skills in adolescents with recent first episode major depression. Journal of Child Psychology and Psychiatry, 46, 995–1005. doi:10.1111/j.1469-7610.2004.00400.x.PubMed

*Lane, K.A. (2012). Visual filtering in children with fetal alcohol spectrum disorder. Proquest Dissertations and Theses.

Lebel, C., Roussotte, F., & Sowell, E. R. (2011). Imaging the impact of prenatal alcohol exposure on the structure of the developing human brain. Neuropsychology Review, 21, 102–118. doi:10.1007/s11065-011-9163-0.PubMedCentralPubMed

*Lee, K. T., Mattson, S. N., & Riley, E. P. (2004). Classifying children with heavy prenatal alcohol exposure using measures of attention. Journal of the International Neuropsychological Society, 10, 271–277. doi:10.1017/0S1355617704102142.PubMed

Lehto, J. E., Juujärvi, P., Kooistra, L., & Pulkkinen, L. (2003). Dimensions of executive functioning: evidence from children. British Journal of Developmental Psychology, 21, 59–80. doi:10.1348/026151003321164627.

*Lestideau, O. (2008). Attention and executive functioning of children with fetal alcohol spectrum disorders. Proquest Dissertations and Theses.

Levy, R., & Goldman-Rakic, P.S. (2000). Segregation of working memory functions within the dorsolateral prefrontal cortex. In Executive Control and the Frontal Lobe: Current Issues (pp. 23–32). Springer Berlin Heidelberg.

Lewin, A. B., Larson, M. J., Park, J. M., McGuire, J. F., Murphy, T. K., & Storch, E. A. (2014). Neuropsychological functioning in youth with obsessive compulsive disorder: an examination of executive function and memory impairment. Psychiatry Research, 216, 108–115. doi:10.1016/j.psychres.2014.01.014.PubMed

Liu, Y., & Wang, Y. (2002). Gender difference of neuropsychological function in attention deficit hyperactivity disorder. Chinese Mental Health Journal, 16, 403–406.

Luciana, M., Conklin, H. M., Hooper, C. J., & Yarger, R. S. (2005). The development of nonverbal working memory and executive control processes in adolescents. Child Development, 76, 697–712. doi:10.1111/j.1467-8624.2005.00872.x.PubMed

Mahone, E. M., Hagelthorn, K. M., Cutting, L. E., Schuerholz, L. J., Pelletier, S. F., Rawlins, C., & Denckla, M. B. (2002). Effects of IQ on executive function measures in children with ADHD. Child Neuropsychology, 8, 52–65. doi:10.1076/chin.8.1.52.8719.PubMed

Malisza, K. L., Allman, A. A., Shiloff, D., Jakobson, L., Longstaffe, S., & Chudley, A. E. (2012). Evaluation of spatial working memory function in children and adults with fetal alcohol spectrum disorders: a functional magnetic resonance imaging study. Pediatric Research, 58, 1150–1157. doi:10.1203/01.pdr.0000185479.92484.a1.

Manji, S., Pei, J., Loomes, C., & Rasmussen, C. (2009). A review of the verbal and visual memory impairments in children with foetal alcohol spectrum disorders. Developmental Neurorehabilitation, 12, 239–247. doi:10.1080/17518420902980118.PubMed

Mattson, S. N., & Riley, E. P. (2000). Parent ratings of behavior in children with heavy prenatal alcohol exposure and IQ‐matched controls. Alcoholism: Clinical and Experimental Research, 24, 226–231. doi:10.1111/j.1530-0277.2000.tb04595.x.

Mattson, S. N., Riley, E. P., Gramling, L., Delis, D. C., & Jones, K. L. (1997). Heavy prenatal alcohol exposure with or without physical features of fetal alcohol syndrome leads to IQ deficits. The Journal of Pediatrics, 131, 718–721. doi:10.1016/S0022-3476(97)70099-4.PubMed

*Mattson, S. N., Goodman, A. M., Caine, C., Delis, D. C., & Riley, E. P. (1999). Executive functioning in children with heavy prenatal alcohol exposure. Alcoholism: Clinical and Experimental Research, 23, 1808–1815. doi:10.1111/j.1530-0277.1999.tb04077.x.

*Mattson, S. N., Roesch, S. C., Fagerlund, Å., Autti‐Rämö, I., Jones, K. L., May, P. A., & Riley, E. P. (2010). Toward a neurobehavioral profile of fetal alcohol spectrum disorders. Alcoholism: Clinical and Experimental Research, 34, 1640–1650. doi:10.1111/j.1530-0277.2010.01250.x.

Mattson, S. N., Crocker, N., & Nguyen, T. T. (2011). Fetal alcohol spectrum disorders: neuropsychological and behavioral features. Neuropsychology Review, 21, 81–101. doi:10.1007/s11065-011-9167-9.PubMedCentralPubMed

*Mattson, S. N., Roesch, S. C., Glass, L., Deweese, B. N., Coles, C. D., Kable, J. A., & Riley, E. P. (2013). Further development of a neurobehavioral profile of fetal alcohol spectrum disorders. Alcoholism: Clinical and Experimental Research, 37, 517–528. doi:10.1111/j.1530-0277.2012.01952.x.

May, P. A., Gossage, J. P., Kalberg, W. O., Robinson, L. K., Buckley, D., Manning, M., & Hoyme, H. E. (2009). Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in‐school studies. Developmental Disabilities Research Reviews, 15, 176–192. doi:10.1002/ddrr.68.PubMed

*McGee, C. L., Schonfeld, A. M., Roebuck-Spencer, T. M., Riley, E. P., & Mattson, S. N. (2008). Children with heavy prenatal alcohol exposure demonstrate deficits on multiple measures of concept formation. Alcoholism: Clinical and Experimental Research, 32, 1388–1397. doi:10.1111/j.1530-0277.2008.00707.x.

Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter, A., & Wager, T. D. (2000). The unity and diversity of executive functions and their contributions to complex “frontal lobe” tasks: a latent variable analysis. Cognitive Psychology, 41, 49–100. doi:10.1006/cogp.1999.0734.PubMed

Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of Internal Medicine, 151, 264–269. doi:10.7326/0003-4819-151-4-200908180-00135.PubMed

Monsell, S. (1996). Control of mental processes. In V. Bruce (Ed.), Unsolved mysteries of the mind: Tutorial essays in cognition (pp. 93–148). Hove: Erlbaum.

Morris, N., & Jones, D. M. (1990). Memory updating in working memory: the role of the central executive. British Journal of Psychology, 81, 111–121. doi:10.1111/j.2044-8295.1990.tb02349.x.

Nakahara, K., Hayashi, T., Konishi, S., & Miyashita, Y. (2002). Functional MRI of macaque monkeys performing a cognitive set-shifting task. Science, 295, 1532–1536. doi:10.1126/science.1067653.PubMed

Nash, K., Stevens, S., Greenbaum, R., Weiner, J., Koren, G., & Rovet, J. (2015). Improving executive functioning in children with fetal alcohol spectrum disorders. Child Neuropsychology, 21, 191–209. doi:10.1080/09297049.2014.889110.PubMed

Newcorn, J. H., Halperin, J. M., Jensen, P. S., Abikoff, H. B., Arnold, L. E., Cantwell, D. P., & Vitiello, B. (2001). Symptom profiles in children with ADHD: effects of comorbidity and gender. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 137–146. doi:10.1097/00004583-200102000-00008.PubMed

Nigg, J. T. (2000). On inhibition/disinhibition in developmental psychopathology: Views from cognitive and personality psychology and a working inhibition taxonomy. Psychological Bulletin, 126, 220–246. doi:10.1037/0033-2909.126.2.220

*Noland, J. S., Singer, L. T., Arendt, R. E., Minnes, S., Short, E. J., & Bearer, C. F. (2003). Executive functioning in preschool-age children prenatally exposed to alcohol, cocaine, and marijuana. Alcohol Clinical Experimental Research, 27, 647–656.

*Norman, A. L., O'Brien, J. W., Spadoni, A. D., Tapert, S. F., Jones, K. L., Riley, E. P., & Mattson, S. N. (2013). A functional magnetic resonance imaging study of spatial working memory in children with prenatal alcohol exposure: contribution of familial history of alcohol use disorders. Alcoholism: Clinical and Experimental Research, 37, 132-140. doi:10.1111/j.1530-0277.2012.01880.x.

*O’Brien, J. W., Norman, A. L., Fryer, S. L., Tapert, S. F., Paulus, M. P., Jones, K. L., & Mattson, S. N. (2013). Effect of predictive cuing on response inhibition in children with heavy prenatal alcohol exposure. Alcoholism: Clinical and Experimental Research, 37, 644–654. doi:10.1111/acer.12017.

*O’Hare, E. D., Lu, L. H., Houston, S. M., Bookheimer, S. Y., Mattson, S. N., O’Connor, M. J., et al. (2009). Altered frontal-parietal functioning during verbal working memory in children and adolescents with heavy prenatal alcohol exposure. Human Brain Mapping, 30, 3200–3208. doi:10.1002/hbm.20741.PubMedCentralPubMed

O’Leary, C. M., Nassar, N., Zubrick, S. R., Kurinczuk, J. J., Stanley, F., & Bower, C. (2010). Evidence of a complex association between dose, pattern and timing of prenatal alcohol exposure and child behaviour problems. Addiction, 105, 74–86. doi:10.1111/j.1360-0443.2009.02756.x.PubMed

Oosterlaan, J., Scheres, A., & Sergeant, J. A. (2005). Which executive functioning deficits are associated with AD/HD, ODD/CD and comorbid AD/HD+ ODD/CD? Journal of Abnormal Child Psychology, 33, 69–85. doi:10.1007/s10802-005-0935-y.PubMed

Osório, A., Cruz, R., Sampaio, A., Garayzábal, E., Martínez-Regueiro, R., Gonçalves, Ó. F., & Fernández-Prieto, M. (2012). How executive functions are related to intelligence in Williams syndrome. Research in Developmental Disabilities, 33, 1169–1175. doi:10.1016/j.ridd.2012.02.003.PubMed

Owens, M., Stevenson, J., Hadwin, J. A., & Norgate, R. (2012). Anxiety and depression in academic performance: an exploration of the mediating factors of worry and working memory. School Psychology International, 33, 433–449. doi:10.1177/0143034311427433.

*Paolozza, A., Titman, R., Brien, D., Munoz, D. P., & Reynolds, J. N. (2013). Altered accuracy of saccadic eye movements in children with fetal alcohol spectrum disorder. Alcoholism: Clinical and Experimental Research, 37, 1491–1498. doi:10.1111/acer.12119.

*Paolozza, A., Rasmussen, C., Pei, J., Hanlon-Dearman, A., Nikkel, S. M., Andrew, G., & Reynolds, J. N. (2014a). Deficits in response inhibition correlate with oculomotor control in children with fetal alcohol spectrum disorder and prenatal alcohol exposure. Behavioural Brain Research, 259, 97–105. doi:10.1016/j.bbr.2013.10.040.PubMed

*Paolozza, A., Rasmussen, C., Pei, J., Hanlon-Dearman, A., Nikkel, S. M., Andrew, G., & Reynolds, J. N. (2014b). Working memory and visuospatial deficits correlate with oculomotor control in children with fetal alcohol spectrum disorder. Behavioural Brain Research, 263, 70–79. doi:10.1016/j.bbr.2014.01.024.PubMed

Pennington, B. F., & Ozonoff, S. (1996). Executive functions and developmental psychopathology. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 37, 51–87. doi:10.1111/j.1469-7610.1996.tb01380.x.PubMed

Pincus, T., Miles, C., Froud, R., Underwood, M., Carnes, D., & Taylor, S. J. (2011). Methodological criteria for the assessment of moderators in systematic reviews of randomised controlled trials: a consensus study. BMC Medical Research Methodology, 11, 14. doi:10.1186/1471-2288-11-14.PubMedCentralPubMed

Pulsifer, M. B. (1996). The neuropsychology of mental retardation. Journal of the International Neuropsychological Society, 2, 159–176. doi:10.1017/S1355617700001016.PubMed

*Quattlebaum, J. L., & O’Connor, M. J. (2013). Higher functioning children with prenatal alcohol exposure: is there a specific neurocognitive profile? Child Neuropsychology, 19, 561–578. doi:10.1080/09297049.2012.713466.PubMed

Rasmussen, C. (2005). Executive functioning and working memory in fetal alcohol spectrum disorder. Alcoholism: Clinical and Experimental Research, 29, 1359–1367. doi:10.1097/01.alc.0000175040.91007.d0.

Rasmussen, C., & Bisanz, J. (2009). Executive functioning in children with fetal alcohol spectrum disorders: profiles and age-related differences. Child Neuropsychology, 15, 201–215. doi:10.1080/09297040802385400.PubMed

*Rasmussen, C., & Bisanz, J. (2011). The relation between mathematics and working memory in young children with fetal alcohol spectrum disorders. The Journal of Special Education, 45, 184–191. doi:10.1177/0022466909356110.

Rasmussen, C., Horne, K., & Witol, A. (2006). Neurobehavioral functioning in children with fetal alcohol spectrum disorder. Child Neuropsychology, 12, 453–468. doi:10.1080/09297040600646854.PubMed

*Rasmussen, C., Wyper, K., & Talwar, V. (2009). The relation between theory of mind and executive functions in children with fetal alcohol spectrum disorders. Canadian Journal of Clinical Pharmacology, 16, e370–e380.PubMed

*Rasmussen, C., Tamana, S., Baugh, L., Andrew, G., Tough, S., & Zwaigenbaum, L. (2013). Neuropsychological impairments on the NEPSY-II among children with FASD. Child Neuropsychology, 19, 337–349. doi:10.1080/09297049.2012.658768.PubMed

Riley, E. P., Infante, M. A., & Warren, K. R. (2011). Fetal alcohol spectrum disorders: an overview. Neuropsychology Review, 21, 73–80. doi:10.1007/s11065-011-9166-x.PubMedCentralPubMed

Rosenthal, R. (1991). Effect sizes: Pearson’s correlation, its display via the BESD, and alternative indices. American Psychologist, 46, 1086–1087. doi:10.1037/0003-066X.46.10.1086.

*Roussotte, F. F., Bramen, J. E., Nunez, S. C., Quandt, L. C., Smith, L., O’Connor, M. J., & Sowell, E. R. (2011). Abnormal brain activation during working memory in children with prenatal exposure to drugs of abuse: the effects of methamphetamine, alcohol, and polydrug exposure. NeuroImage, 54, 3067–3075. doi:10.1016/j.neuroimage.2010.10.072.PubMedCentralPubMed

Schonfeld, A.M. (2003). Moral judgement and reasoning in children and adolescents with prenatal alcohol exposure. Proquest Dissertations and Theses.

*Schonfeld, A. M., Mattson, S. N., Lang, A. R., Delis, D. C., & Riley, E. P. (2001). Verbal and nonverbal fluency in children with heavy prenatal alcohol exposure. Journal of Studies on Alcohol and Drugs, 62, 239.

*Spadoni, A. D., Bazinet, A. D., Fryer, S. L., Tapert, S. F., Mattson, S. N., & Riley, E. P. (2009). BOLD response during spatial working memory in youth with heavy prenatal alcohol exposure. Alcoholism: Clinical and Experimental Research, 33, 2067–2076. doi:10.1111/j.1530-0277.2009.01046.x.

Steinhausen, H. C., & Spohr, H. L. (1998). Long-term outcome of children with fetal alcohol syndrome: psychopathology, behavior and intelligence. Alcoholism: Clinical and Experimental Research, 22, 334–338. doi:10.1111/j.1530-0277.1998.tb03657.x.

*Steinmann, T.P., Andrew, C.M., Thomsen, C.E., Kjar, T.W., Meintjes, E.M., Molteno, C.D., & Sorensen, H. B. (2011). An auditory Go/No-Go study of event-related potentials in children with fetal alcohol spectrum disorders. In Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE, 789–792. doi: 10.1109/IEMBS.2011.6090181.

Stratton, K., Howe, C., & Battaglia, F. (1996). Fetal alcohol syndrome: Diagnosis, epidemiology, prevention, and treatment. Washington: National Academy.

Streissguth, A. P., Barr, H. M., Sampson, P. D., Darby, B. L., & Martin, D. C. (1989). IQ at age 4 in relation to maternal alcohol use and smoking during pregnancy. Developmental Psychology, 25, 3–11. doi:10.1037/0012-1649.25.1.3.

Streissguth, A. P., Aase, J. M., Clarren, S. K., Randels, S. P., LaDue, R. A., & Smith, D. F. (1991). Fetal alcohol syndrome in adolescents and adults. Journal of the American Medical Association, 265, 1961–1967. doi:10.1001/jama.1991.03460150065025.PubMed

Tanabe, M. K., Whitaker, A. M., O’Callaghan, E. T., Murray, J., & Houskamp, B. M. (2014). Intellectual ability as a predictor of performance on the Wisconsin card-sorting test. Applied Neuropsychology: Child, 3(4), 275–283. doi:10.1080/21622965.2012.757700.

Thomspon, S. G., & Higgins, J. P. T. (2002). How should meta-regression analyses be undertaken and interpreted? Statistics in Medicine, 21, 1559–1573.

Thorell, L. B., & Wåhlstedt, C. (2006). Executive functioning deficits in relation to symptoms of ADHD and/or ODD in preschool children. Infant and Child Development, 15, 503–518. doi:10.1002/icd.475.

*Vaurio, L. (2012). Emotion-based decision making in children with fetal alcohol spectrum disorders. Proquest Dissertations and Theses.

*Vaurio, L., Riley, E. P., & Mattson, S. N. (2008). Differences in executive functioning in children with heavy prenatal alcohol exposure or attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society, 14, 119–129. doi:10.1017/S1355617708080144.PubMedCentralPubMed

*Vaurio, L., Riley, E. P., & Mattson, S. N. (2011). Neuropsychological comparison of children with heavy prenatal alcohol exposure and an IQ-matched comparison group. Journal of the International Neuropsychological Society, 17, 463–473. doi:10.1017/S1355617711000063.PubMedCentralPubMed

Ware, A. L., Crocker, N., O’Brien, J. W., Deweese, B. N., Roesch, S. C., Coles, C. D., & Mattson, S. N. (2012). Executive function predicts adaptive behavior in children with histories of heavy prenatal alcohol exposure and attention‐deficit/hyperactivity disorder. Alcoholism: Clinical and Experimental Research, 36, 1431–1441. doi:10.1111/j.1530-0277.2011.01718.x.

Willcutt, E. G., Doyle, A. E., Nigg, J. T., Faraone, S. V., & Pennington, B. F. (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biological Psychiatry, 57, 1336–1346. doi:10.1016/j.biopsych.2005.02.006.PubMed

Witt, S. T., & Stevens, M. C. (2013). fMRI task parameters influence hemodynamic activity in regions implicated in mental set switching. NeuroImage, 65, 139–151. doi:10.1016/j.neuroimage.2012.09.072.PubMedCentralPubMed

*Wozniak, J. R., Mueller, B. A., Bell, C. J., Muetzel, R. L., Hoecker, H. L., Boys, C. J., & Lim, K. O. (2013). Global functional connectivity abnormalities in children with fetal alcohol spectrum disorders. Alcoholism: Clinical and Experimental Research, 37, 748–756. doi:10.1111/acer.12024.

Zelazo, P. D., & Müller, U. (2002). Executive function in typical and atypical development. In U. Goswami (Ed.), Blackwell handbook of childhood cognitive development. Blackwell handbooks of developmental psychology (pp. 445–469). Malden: Blackwell Publishing.

Titel: Executive Functioning in Children and Adolescents Prenatally Exposed to Alcohol: A Meta-Analytic Review
verfasst von: Jennifer E. Khoury
Karen Milligan
Todd A. Girard
Publikationsdatum: 01.06.2015
Verlag: Springer US
Erschienen in: Neuropsychology Review / Ausgabe 2/2015
Print ISSN: 1040-7308
Elektronische ISSN: 1573-6660
DOI: https://doi.org/10.1007/s11065-015-9289-6

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Thrombektomie auch bei großen Infarkten von Vorteil

16.05.2024 Ischämischer Schlaganfall Nachrichten

Auch ein sehr ausgedehnter ischämischer Schlaganfall scheint an sich kein Grund zu sein, von einer mechanischen Thrombektomie abzusehen. Dafür spricht die LASTE-Studie, an der Patienten und Patientinnen mit einem ASPECTS von maximal 5 beteiligt waren.

Schwindelursache: Massagepistole lässt Otholiten tanzen

14.05.2024 Benigner Lagerungsschwindel Nachrichten

Wenn jüngere Menschen über ständig rezidivierenden Lagerungsschwindel klagen, könnte eine Massagepistole der Auslöser sein. In JAMA Otolaryngology warnt ein Team vor der Anwendung hochpotenter Geräte im Bereich des Nackens.

Schützt Olivenöl vor dem Tod durch Demenz?

10.05.2024 Morbus Alzheimer Nachrichten

Konsumieren Menschen täglich 7 Gramm Olivenöl, ist ihr Risiko, an einer Demenz zu sterben, um mehr als ein Viertel reduziert – und dies weitgehend unabhängig von ihrer sonstigen Ernährung. Dafür sprechen Auswertungen zweier großer US-Studien.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2015

The Still Enigmatic Syndrome of Transient Global Amnesia: Interactions Between Neurological and Psychopathological Factors

Procedural Learning and Memory Rehabilitation in Korsakoff’s Syndrome - a Review of the Literature

Decision Making Under Objective Risk Conditions–a Review of Cognitive and Emotional Correlates, Strategies, Feedback Processing, and External Influences

The Potential Utility of Eye Movements in the Detection and Characterization of Everyday Functional Difficulties in Mild Cognitive Impairment

Historical Perspectives on the Behavioral Function of the Insula