Erschienen in:
01.07.2021 | Clinical Guides in Oncology
GEIS-SEHOP clinical practice guidelines for the treatment of rhabdomyosarcoma
verfasst von:
S. Gallego, D. Bernabeu, M. Garrido-Pontnou, G. Guillen, N. Hindi, A. Juan-Ribelles, C. Márquez, C. Mata, J. Orcajo, G. Ramírez, M. Ramos, C. Romagosa, D. Ruano, P. Rubio, R. Vergés, C. Valverde, GEIS (Grupo Español de Investigación en Sarcomas), SEHOP (Sociedad Española de Hematología y Oncología Pediátrica)
Erschienen in:
Clinical and Translational Oncology
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Ausgabe 12/2021
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Abstract
Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma (STS) in children and adolescents. In Spain the annual incidence is 4.4 cases per million children < 14 years. It is an uncommon neoplasm in adults, but 40% of RMS are diagnosed in patients over 20 years of age, representing 1% of all STS in this age group. RMS can appear anywhere in the body, with some sites more frequently affected including head and neck, genitourinary system and limbs. Assessment of a patient with suspicion of RMS includes imaging studies (MRI, CT, PET-CT) and biopsy. All patients with RMS should receive chemotherapy, either at diagnosis in advanced or metastatic stages, or after initial resection in early local stages. Local control includes surgery and/or radiotherapy depending on site, stage, histology and response to chemotherapy. This guide provides recommendations for diagnosis, staging and treatment of this neoplasm.