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Pediatric Nephrology

Erschienen in:

12.11.2017 | Educational Review

Hearing loss and renal syndromes

verfasst von: Paul J. Phelan, Michelle N. Rheault

Erschienen in: Pediatric Nephrology | Ausgabe 10/2018

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Abstract

The association between ear and kidney abnormalities has long been recognized; however, the connection between these two disparate organs is not always straightforward. Although Alport syndrome is the most well-known, there are over 20 disorders that need to be considered in the differential diagnosis of patients with both ear and kidney abnormalities. Commonalities are present between the kidney and ear in a number of structural proteins, developmentally important transcription factors, ciliary proteins, and channel proteins, and mutations in these pathways can lead to disease in both organ systems. This manuscript reviews the congenital disorders with both hearing and kidney manifestations.

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Titel: Hearing loss and renal syndromes
verfasst von: Paul J. Phelan
Michelle N. Rheault
Publikationsdatum: 12.11.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 10/2018
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-017-3835-9

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Hearing loss and renal syndromes

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