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10.08.2016 | Case Report

Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS

verfasst von: Estelle Lauer, Max Villa, Morgane Jotterand, Raquel Vilarino, Marc Bollmann, Katarzyna Michaud, Silke Grabherr, Marc Augsburger, Aurélien Thomas

Erschienen in: International Journal of Legal Medicine | Ausgabe 2/2017

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Abstract

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was performed to map elements in thin formalin-fixed paraffin-embedded tissue sections of two forensic cases with firearm and electrocution injuries, respectively. In both cases, histological examination of the wounded tissue regions revealed the presence of exogenous aggregates that may be interpreted as metallic depositions. The use of imaging LA-ICP-MS allowed us to unambiguously determine the elemental composition of the observed aggregates assisting the pathologist in case assessments. To the best of our knowledge, we demonstrate for the first time the use of imaging LA-ICP-MS as a complementary tool for forensic pathologists and toxicologists in order to map the presence of metals and other elements in thin tissue sections of post-mortem cases.

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Titel: Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS
verfasst von: Estelle Lauer
Max Villa
Morgane Jotterand
Raquel Vilarino
Marc Bollmann
Katarzyna Michaud
Silke Grabherr
Marc Augsburger
Aurélien Thomas
Publikationsdatum: 10.08.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: International Journal of Legal Medicine / Ausgabe 2/2017
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-016-1414-4

Springer Medizin

Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS

Abstract

Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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