Ausgabe 2/2003
Inhalt (9 Artikel)
Introduction: Role of Modeling and Simulation in Clinical Development of Anticancer Agents
Alex Sparreboom, Mats O. Karlsson
Use of Positron Emission Tomography in Anticancer Drug Development
Eric O. Aboagye, Patricia M. Price
Clinical Pharmacokinetic/Pharmacodynamic and Physiologically based Pharmacokinetic Modeling in New Drug Development: The Capecitabine Experience
Karen S. Blesch, Ronald Gieschke, Yuko Tsukamoto, Bruno G. Reigner, Hans U. Burger, Jean-Louis Steimer
Pharmacokinetic–pharmacodynamic Guided Trial Design in Oncology
Ch. van Kesteren, R.A.A. Mathôt, J.H. Beijnen, J.H.M. Schellens
Clinical Trial Design for Target Specific Anticancer Agents
Ronald Hoekstra, Jaap Verweij, Ferry A.L.M. Eskens