Ausgabe 4/2010
Inhalt (19 Artikel)
Evaluation Of 5-hydroxy-2,3-diaryl (substituted)-cyclopent-2-en-1-ones as cis-restricted analogues of combretastatin A-4 as novel anti angiogenic and anticancer agents
Vinod Kumar Sanna, Manu Jaggi, Vadlapudi Kumar, Anand C. Burman
Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity
Satoki Nakamura, Mitsuji Yamashita, Daisuke Yokota, Isao Hirano, Takaaki Ono, Michio Fujie, Kiyoshi Shibata, Taishi Niimi, Takuya Suyama, Kasthuraiah Maddali, Kazuhide Asai, Junko Yamashita, Yukiko Iguchi, Kazunori Ohnishi
The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral oncogenesis
G. Harish Kumar, R. Vidya Priyadarsini, G. Vinothini, P. Vidjaya Letchoumy, S. Nagini
MER1, a novel organic arsenic derivative, has potent PML-RARα- independent cytotoxic activity against leukemia cells
Mirna Golemovic, Alfonso Quintás-Cardama, Taghi Manshouri, Nada Orsolic, Hatice Duzkale, Mary Johansen, Emil J. Freireich, Hagop Kantarjian, Ralph A. Zingaro, Srdan Verstovsek
The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines
Brigette B. Y. Ma, Vivian W. Y. Lui, Edwin P. Hui, Cecilia P. Y. Lau, Kakiu Ho, Margaret H. L. Ng, S. H. Cheng, Sai-Wah Tsao, Anthony T. C. Chan
Cytotoxic activities of new iron(III) and nickel(II) chelates of some S-methyl-thiosemicarbazones on K562 and ECV304 cells
Belkıs Atasever, Bahri Ülküseven, Tülay Bal-Demirci, Serap Erdem-Kuruca, Zeynep Solakoğlu
Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines
D. M. Collins, J. Crown, N. O’Donovan, A. Devery, F. O’Sullivan, L. O’Driscoll, M. Clynes, R. O’Connor
The effect of cellular environment and p53 status on the mode of action of the platinum derivative LA-12
Eva Roubalová, Veronika Kvardová, Roman Hrstka, Šárka Bořilová, Eva Michalová, Lenka Dubská, Petr Müller, Petr Sova, Bořivoj Vojtěšek
Synthesis and identification of a new class of (S)-2,6-diamino-4,5,6,7-tetrahydrobenzo[d]thiazole derivatives as potent antileukemic agents
D. S. Prasanna, C. V. Kavitha, B. Raghava, K. Vinaya, S. R. Ranganatha, Sathees C. Raghavan, K. S. Rangappa
Tea polyphenols inhibit cyclooxygenase-2 expression and block activation of nuclear factor-kappa B and Akt in diethylnitrosoamine induced lung tumors in Swiss mice
Preeti Roy, Nidhi Nigam, Madhulika Singh, Jasmine George, Smita Srivastava, Hasnain Naqvi, Yogeshwer Shukla
Pyrimidinyl-arylpropionic acid derivatives: viable resources in the development of new antineoplastic agents
Xishan Xiong, Li Wang, Yangliang Ye, Lili Fu, Minli Chen, Qingyi Wang, Moyan Liu, Jing Tang, Bing Dai, Jianhua Shen, Changlin Mei
Purine analogs sensitize the multidrug resistant cell line (NCI-H460/R) to doxorubicin and stimulate the cell growth inhibitory effect of verapamil
Milica Pešić, Ana Podolski, Ljubiša Rakić, Sabera Ruždijić
Novel combretastatin A-4 derivative XN0502 induces cell cycle arrest and apoptosis in A549 cells
Hong Zhu, Jun Zhang, Na Xue, Yongzhou Hu, Bo Yang, Qiaojun He
Phase I trial of weekly docetaxel, weekly doxorubicin, daily oral cyclophosphamide, and G-CSF (ConTAC Regimen)in advanced malignancies
Robert Wesolowski, David Peereboom, Patricia Weiss, Paul Elson, George Thomas Budd
A dose escalation, safety, and tolerability study of MN-029 in patients with advanced solid tumors
Anne M. Traynor, Michael S. Gordon, Dona Alberti, David S. Mendelson, Mark S. Munsey, George Wilding, Richard E. Gammans, William L. Read
Yttrium-90-ibritumomab tiuxetan in combination with intravenous busulfan, cyclophosphamide, and etoposide followed by autologous stem cell transplantation in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
Byung Woog Kang, Won Seog Kim, Chul Kim, Geundoo Jang, Sung Sook Lee, Yoon Hee Choi, Dae Ho Lee, Sang We Kim, Shin Kim, Jin-Sook Ryu, Jooryung Huh, Jung Shin Lee, Cheolwon Suh
Phase II trial of sunitinib in patients with relapsed or refractory germ cell tumors
Darren R. Feldman, Stefan Turkula, Michelle S. Ginsberg, Nicole Ishill, Sujata Patil, Maryann Carousso, George J. Bosl, Robert J. Motzer
Inadequacy of size-based response criteria to assess the efficacy of trabectedin among metastatic sarcoma patients
Antoine Hollebecque, Antoine Adenis, Sophie Taieb, Claudia Lebedinsky, Nicolas Penel
Reversible cardiogenic shock following 5-Fluorouracil infusion
Charles Ferté, Carlos Gomez Roca, Yohann Loriot, Rastislav Bahleda, Cristian Moldovan, Ariel Cohen, Hassan Izzedine, Jean-Charles Soria, Stephane Ederhy