Ausgabe 5/2010
Inhalt (20 Artikel)
Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib
Ansgar Brüning, Petra Burger, Marianne Vogel, Andrea Gingelmaier, Klaus Friese, Alexander Burges
Effect of a Vitamin D3 derivative (B3CD) with postulated anti-cancer activity in an ovarian cancer animal model
Thilo S. Lange, Ashley R. Stuckey, Katina Robison, Kyu Kwang Kim, Rakesh K. Singh, Christina A. Raker, Laurent Brard
An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines
Efstathia Giannopoulou, Konstantinos Dimitropoulos, Andreas A. Argyriou, Angelos K. Koutras, Fotinos Dimitrakopoulos, Haralabos P. Kalofonos
Development of a new fully human anti-CD20 monoclonal antibody for the treatment of B-cell malignancies
Gadi Gazit Bornstein, Christophe Quéva, Mohammad Tabrizi, Anne van Abbema, Carlos Chavez, Ping Wang, Orit Foord, Kiran Ahluwalia, Naomi Laing, Sandhya Raja, Shenghua Wen, Larry L. Green, Xiaodong Yang, Carl Webster, Ross Stewart, David Blakey
The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells
Sharon A. Mason, Sarah-Jane Cozzi, Carly J. Pierce, Sandra J. Pavey, Peter G. Parsons, Glen M. Boyle
Triphenyltin(IV) 2-[(E)-2-(aryl)-1-diazenyl]benzoates as anticancer drugs: synthesis, structural characterization, in vitro cytotoxicity and study of its influence towards the mechanistic role of some key enzymes
Tushar S. Basu Baul, Anup Paul, Lorenzo Pellerito, Michelangelo Scopelliti, Palwinder Singh, Pooja Verma, Dick de Vos
Synthesis and biological properties of oxazolinodaunorubicin—a new derivative of daunorubicin with a modified daunosamine moiety
Malgorzata Lukawska, Joanna Wietrzyk, Adam Opolski, Janusz Oszczapowicz, Irena Oszczapowicz
In vitro cytotoxic evaluation of novel dichlorodiorgano[N-(2-pyridylmethylene)arylamine]tin(IV) derivatives in human tumor cell lines
Tushar S. Basu Baul, Dick de Vos
Studies on the neuroprotective role of Piper longum in C6 glioma induced rats
Umadevi Subramanian, Sharmila Poongavanam, A. J. Vanisree
Involvement of non-protein thiols, mitochondrial dysfunction, reactive oxygen species and p53 in honey-induced apoptosis
Saravana Kumar Jaganathan, Mahitosh Mandal
A phase I trial of imexon, a pro-oxidant, in combination with docetaxel for the treatment of patients with advanced breast, non-small cell lung and prostate cancer
Stacy Moulder, Navneet Dhillon, Chaan Ng, David Hong, Jennifer Wheler, Aung Naing, Susan Tse, Amy La Paglia, Robert Dorr, Evan Hersh, Michelle Boytim, Razelle Kurzrock
Intravenous administration of Reolysin®, a live replication competent RNA virus is safe in patients with advanced solid tumors
Radharani Gollamudi, Mohammad H. Ghalib, Kavita K. Desai, Imran Chaudhary, Benny Wong, Mark Einstein, Matthew Coffey, George M. Gill, Karl Mettinger, John M. Mariadason, Sridhar Mani, Sanjay Goel
A phase I pharmacokinetic and pharmacodynamic study of CKD-732, an antiangiogenic agent, in patients with refractory solid cancer
Sang Joon Shin, Hei-Cheul Jeung, Joong Bae Ahn, Sun Young Rha, Jae Kyung Roh, Kyung Soo Park, Dal-Hyun Kim, Chin Kim, Hyun Cheol Chung
Phase II study of gemcitabine in combination with vinorelbine versus gemcitabine followed by vinorelbine for metastatic breast cancer
In Hae Park, Jungsil Ro, Keun Seok Lee, Shi Nae Kim, Young Ho Yun, Byung Ho Nam
Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma
Jennifer Wu, Charles Henderson, Lynn Feun, Peter Van Veldhuizen, Philip Gold, Hui Zheng, Theresa Ryan, Lawrence S. Blaszkowsky, HaoBin Chen, Max Costa, Barry Rosenzweig, MaryLynn Nierodzik, Howard Hochster, Franco Muggia, Giovanni Abbadessa, Jonathan Lewis, Andrew X. Zhu
Phase II study of sunitinib malate in head and neck squamous cell carcinoma
Nicholas W. Choong, Mark Kozloff, David Taber, H. Shawn Hu, James Wade III, Percy Ivy, Theodore G. Karrison, Allison Dekker, Everett E. Vokes, Ezra E. W. Cohen
Oral metronomic cyclophosphamide in elderly with metastatic melanoma
Estelle Borne, Eve Desmedt, Alain Duhamel, Xavier Mirabel, Véronique Dziwniel, Cyril Maire, Valérie Florin, Véronique Martinot, Nicolas Penel, Sophie Vercambre-Darras, Laurent Mortier
Sunitinib inducing tumor lysis syndrome in a patient treated for renal carcinoma
Judith Michels, Nathalie Lassau, Marine Gross-Goupil, Christophe Massard, Arnaud Mejean, Bernard Escudier
Anti-tumor effects of nitrosylcobalamin against spontaneous tumors in dogs
Joseph A. Bauer, Gerald Frye, Anne Bahr, Jennifer Gieg, Peter Brofman
Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response
Gurpreet Kaur, Mohammad Athar, M. Sarwar Alam