Ausgabe 2/2020
Inhalt (24 Artikel)
“Hedgehog pathway”: a potential target of itraconazole in the treatment of cancer
Xin Wei, Wu Liu, Jia Qi Wang, Zeyao Tang
Prostate specific membrane antigen (PSMA) in urothelial cell carcinoma (UCC) is associated with tumor grading and staging
Henner Schreiber, Jörg Hänze, Wilhelm Nimphius, Frederik Anton Verburg, Markus Luster, Rainer Hofmann, Axel Hegele
Crosstalk of estrogen receptors and Wnt/β-catenin signaling in endometrial cancer
Mariz Kasoha, Chrisoula Dernektsi, Anita Seibold, Rainer M. Bohle, Zoltan Takacs, Iordache Ioan-Iulian, Erich-Franz Solomayer, Ingolf Juhasz-Böss
YARS as an oncogenic protein that promotes gastric cancer progression through activating PI3K-Akt signaling
Cheng Zhang, Xiaoting Lin, Qian Zhao, Yakun Wang, Fangli Jiang, Congcong Ji, Yanyan Li, Jing Gao, Jian Li, Lin Shen
Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes
Nicole Kiweler, Désirée Wünsch, Matthias Wirth, Nisintha Mahendrarajah, Günter Schneider, Roland H. Stauber, Walburgis Brenner, Falk Butter, Oliver H. Krämer
Clinical features and treatment of 7 Chinese TAFRO syndromes from 96 de novo Castleman diseases: a 10-year retrospective study
Yi Zhang, Shan-Shan Suo, Han-Jin Yang, Xin-Ping Zhou, Liang-Shun You, Wen-Juan Yu, Zhao-Ming Wang, Jie Jin
Long non-coding RNA MALAT1 facilitates the tumorigenesis, invasion and glycolysis of multiple myeloma via miR-1271-5p/SOX13 axis
Na Liu, Song Feng, Huanhuan Li, Xiaoguang Chen, Songting Bai, Yufeng Liu
TERT promoter hotspot mutations and their relationship with TERT levels and telomere erosion in patients with head and neck squamous cell carcinoma
Paolo Boscolo-Rizzo, Silvia Giunco, Enrica Rampazzo, Martina Brutti, Giacomo Spinato, Anna Menegaldo, Marco Stellin, Monica Mantovani, Luigia Bandolin, Marco Rossi, Annarosa Del Mistro, Giancarlo Tirelli, Angelo Paolo Dei Tos, Angela Guerriero, Monia Niero, Maria Cristina Da Mosto, Jerry Polesel, Anita De Rossi
Prolonged time to treatment initiation in advanced pancreatic cancer patients has no major effect on treatment outcome: a retrospective cohort study controlled for lead time bias and waiting time paradox
Stephan Kruger, Karoline Schirle, Michael Haas, Alexander Crispin, Jörg Schirra, Julia Mayerle, Jan G. D’Haese, Wolfgang G. Kunz, Jens Ricke, Steffen Ormanns, Thomas Kirchner, Sebastian Kobold, Matthias Ilmer, Leonie Gebauer, Christoph B. Westphalen, Michael von Bergwelt-Baildon, Jens Werner, Volker Heinemann, Stefan Boeck
Prognostic value of tumor cavitation in extensive-stage small-cell lung cancer patients treated with anlotinib
Dongfang Chen, Jianlin Xu, Yizhuo Zhao, Tianqing Chu, Hua Zhong, Baohui Han, Runbo Zhong
Co-occurring genetic alterations and primary EGFR T790M mutations detected by NGS in pre-TKI-treated NSCLCs
Yuan Tang, Nanying Che, Yang Yu, Yun Gao, Huaiyin Shi, Qin Feng, Bing Wei, Liheng Ma, Min Gao, Jie Ma, Dongmei Lin
Clinical outcomes and prognostic factors of stereotactic body radiation therapy combined with gemcitabine plus capecitabine for locally advanced unresectable pancreatic cancer
Ze-Tian Shen, Han Zhou, Ao-Mei Li, Xiao-Qin Ji, Chang-Chen Jiang, Xi Yuan, Bing Li, Xi-Xu Zhu, Gui-Chun Huang
Superiority of intensity-modulated radiation therapy in nasopharyngeal carcinoma with skull-base invasion
Shufang Liao, Yuan Xie, Yi Feng, Yuanyuan Zhou, Yufei Pan, Jinfang Fan, Jinglin Mi, Xiaoli Qin, Dacheng Yao, Wei Jiang
First-line PD-1/PD-L1 inhibitor plus chemotherapy vs chemotherapy alone for negative or < 1% PD-L1-expressing metastatic non-small-cell lung cancers
Thierry Landre, Gaetan Des Guetz, Kader Chouahnia, Cherifa Taleb, Alain Vergnenègre, Christos Chouaïd
Treatment of refractory germ-cell tumours with single-agent cabazitaxel: a German Testicular Cancer Study Group case series
Christoph Oing, Marcus Hentrich, Anja Lorch, Dietrich Gläser, Holger Rumpold, Sebastian Ochsenreither, Stephan Richter, Annette Dieing, Stefanie Zschäbitz, Ronnie Rodrigues Pereira, Carsten Bokemeyer, Christoph Seidel
Efficacy and safety of first-line pembrolizumab monotherapy in elderly patients (aged ≥ 75 years) with non-small cell lung cancer
Hisao Imai, Satoshi Wasamoto, Ou Yamaguchi, Kensuke Suzuki, Tomohide Sugiyama, Junji Uchino, Hiroyuki Minemura, Takashi Osaki, Hisashi Ishii, Yukihiro Umeda, Keita Mori, Mie Kotake, Hiroshi Kagamu, Nobutoshi Morozumi, Hirokazu Taniguchi, Takashi Kasai, Koichi Minato, Kyoichi Kaira
Tissue factor activity on microvesicles from cancer patients
Fanny Ender, Annika Freund, Tabea Quecke, Corinna Steidel, Piet Zamzow, Nikolas von Bubnoff, Frank Gieseler
Impact of clinical complete response on treatment outcomes in patients with locally advanced HPV-negative oropharyngeal squamous cell carcinoma
Francesca De Felice, Daniela Musio, Gessica Abate, Erika Moscarelli, Nadia Bulzonetti, Vincenzo Tombolini
Comparative analysis of causes and predictors of early death in elderly and young patients with acute promyelocytic leukemia treated with arsenic trioxide
Bo Jin, Yingmei Zhang, Wenyi Hou, Fenglin Cao, Ming Lu, Huiyuan Yang, Xuanyu Tian, Yuan Wang, Jinxiao Hou, Jinyue Fu, Haitao Li, Jin Zhou
Clinical impact of first-line bevacizumab plus chemotherapy in metastatic colorectal cancer of mucinous histology: a multicenter, retrospective analysis on 685 patients
Vincenzo Catalano, Francesca Bergamo, Chiara Cremolini, Bruno Vincenzi, Francesca Negri, Paolo Giordani, Paolo Alessandroni, Rossana Intini, Silvia Stragliotto, Daniele Rossini, Beatrice Borelli, Daniele Santini, Donatella Sarti, Marco B. L. Rocchi, Sara Lonardi, Alfredo Falcone, Vittorina Zagonel, Rodolfo Mattioli, Francesco Graziano
Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib
Julia Eismann, Yujing J. Heng, Johannes M. Waldschmidt, Ioannis S. Vlachos, Kathryn P. Gray, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos, Charles J. Murphy, Sheida Nabavi, Gerburg M. Wulf
Insufficient examined lymph node count underestimates staging in pN3a patients after curative gastrectomy: a multicenter study with external validation
Yinping Dong, Yiran Qiu, Jingyu Deng, Wei Wang, Zhe Sun, Zhenning Wang, Zhiwei Zhou, Huimian Xu, Han Liang
Impact of pathologic complete response on survival after neoadjuvant chemotherapy in early-stage breast cancer: a population-based analysis
Nathalie LeVasseur, J. Sun, L. Gondara, R. Diocee, C. Speers, C. Lohrisch, S. Chia
Percent tumor volume vs American Joint Committee on Cancer staging system subclassification for predicting biochemical recurrence in patients with pathologic T2 prostate cancer
Se Young Choi, Byung Hoon Chi, Bumjin Lim, Yoon Soo Kyung, Dalsan You, In Gab Jeong, Cheryn Song, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim