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Journal of Clinical Immunology OnlineFirst articles

16.11.2022 | Original Article

Efficacy and Safety of Interferon-Gamma in Chronic Granulomatous Disease: a Systematic Review and Meta-analysis

Chronic granulomatous disease (CGD) is a primary immunodeficiency with increased susceptibility to several bacteria, fungi, and mycobacteria, caused by defective or null superoxide production by the NADPH oxidase enzymatic complex [ 1 , 2 ].

Open Access 16.11.2022 | Original Article

BT595, a 10% Human Normal Immunoglobulin, for Replacement Therapy of Primary Immunodeficiency Disease: Results of a Subcohort Analysis in Children

Primary immunodeficiency diseases (PID)/inborn errors of immunity (IEI) are a class of about 430 disorders characterized by an intrinsic defect in the human immune system [ 1 ]. Patients with antibody deficiency, including children, present with …

16.11.2022 | Original Article

Increased Hazard Risk of First Malignancy in Adults with Undetectable Serum IgE: a Retrospective Cohort Study

Immunoglobulin E (IgE) antibody has a pathophysiologic role in allergic disease and may provide protection against helminthic infection [ 1 ]. Little is known about the clinical significance of undetectable serum IgE (IgE deficiency). Limited case …

16.11.2022 | Original Article

Clinical and Genetic Characterization of Patients with Artemis Deficiency in Japan

Severe combined immunodeficiency (SCID) encompasses a group of genetic disorders characterized by a profound impairment in humoral and cellular immunity. Approximately half of patients with SCID in Japan present with a T − B + NK − phenotype caused …

15.11.2022 | Original Article

A Heterozygous Gain-of-Function Variant in IKBKB Associated with Autoimmunity and Autoinflammation

Biallelic loss-of-function variants of the IKBKB gene, encoding for the inhibitor kappa B kinase 2 (IKK2 or IKKβ) protein, cause autosomal recessive severe combined immunodeficiency (SCID) with relatively normal T and B cell counts [ 1 ].

Über diese Zeitschrift

The Journal of Clinical Immunology is an international journal that helps researchers and academic clinicians keep current on investigative basic immunology and diseases related to the immune system. This well-established journal publishes articles on basic, translational, and clinical studies in all aspects of immunology, including animal models of human diseases.

Metadaten
Titel
Journal of Clinical Immunology
Abdeckung
Volume 17/1997 - Volume 42/2022
Verlag
Springer US
Elektronische ISSN
1573-2592
Print ISSN
0271-9142
Zeitschriften-ID
10875
DOI
https://doi.org/10.1007/10875.1573-2592

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