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Erschienen in: Surgical and Radiologic Anatomy 9/2018

06.06.2018 | Original Article

Magnetic resonance morphometry of the adult normal lumbar intervertebral space

verfasst von: Apostolos H. Fyllos, Dimitrios L. Arvanitis, Apostolos H. Karantanas, Sokratis E. Varitimidis, Michael Hantes, Aristeidis H. Zibis

Erschienen in: Surgical and Radiologic Anatomy | Ausgabe 9/2018

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Abstract

Purpose

This study aims to: (a) quantify and evaluate normal relationships between neighboring spinal units using MR imaging indices, (b) propose an easy-to-apply-and-reproduce method of estimating the correct amount of distraction when surgically restoring a collapsed intervertebral disc, based on individualized measurements.

Methods

This is a retrospective cross-sectional MR imaging study of 119 adult subjects, aged 18–54, asymptomatic for low back pain. Each of the examinees should demonstrate two or more consecutive intervertebral discs classified as Pfirrmann grade I or II to be included. We measured and studied the relationships of disc height index, Dabbs index, Farfan index, disc convexity index and mean and posterior disc height per spinal level using multiple regression analysis. All measurements were tested for intra- and interobserver agreement by two raters.

Results

DHI, Dabbs, Farfan, and mean disc height had a statistically significant correlation with the spinal level and age. Our results were highly reproducible, with excellent inter- and intraobserver agreement and reliability between two raters (ICC = 0.992 and 0.994, respectively). Furthermore, we expressed each intervertebral space as a percentage of its adjacent space, introducing the coefficient α factor for every intervertebral space.

Conclusions

Our results suggest that a normal values’ database to refer during preoperative planning of correction of a degenerated intervertebral disc is feasible. Our study offers new anatomical and radiological insight in terms of spinal measurements and their potential correlation with current surgical techniques. A new approach for calculating disc space as an expression of its adjacent disc has been introduced with various potential applications.
Literatur
4.
Zurück zum Zitat Dabbs VM, Dabbs LG (1990) Correlation between disc height narrowing and low-back pain. Spine (Phila Pa 1976) 15:1366–1369CrossRef Dabbs VM, Dabbs LG (1990) Correlation between disc height narrowing and low-back pain. Spine (Phila Pa 1976) 15:1366–1369CrossRef
6.
Zurück zum Zitat Farfan HF, Cossette JW, Robertson GH, Wells RV, Kraus H (1970) The effects of torsion on the lumbar intervertebral joints: the role of torsion in the production of disc degeneration. J Bone Joint Surg Am 52:468–497CrossRefPubMed Farfan HF, Cossette JW, Robertson GH, Wells RV, Kraus H (1970) The effects of torsion on the lumbar intervertebral joints: the role of torsion in the production of disc degeneration. J Bone Joint Surg Am 52:468–497CrossRefPubMed
7.
Zurück zum Zitat Fleiss J (1986) The design and analysis of clinical experiments. Wiley, New York Fleiss J (1986) The design and analysis of clinical experiments. Wiley, New York
8.
Zurück zum Zitat Frobin W, Brinckmann P, Biggemann M, Tillotson M, Burton K (1997) Precision measurement of disc height, vertebral height and sagittal plane displacement from lateral radiographic views of the lumbar spine. Clin Biomech (Bristol Avon) 12(Suppl 1):S1–S63 Frobin W, Brinckmann P, Biggemann M, Tillotson M, Burton K (1997) Precision measurement of disc height, vertebral height and sagittal plane displacement from lateral radiographic views of the lumbar spine. Clin Biomech (Bristol Avon) 12(Suppl 1):S1–S63
9.
Zurück zum Zitat Froholdt A, Brox JI, Reikerås O, Leivseth G (2013) Disc height and sagittal alignment in operated and non-operated levels in the lumbar spine at long-term follow-up: a case-control study. Open Orthop J 7:258–263CrossRefPubMedPubMedCentral Froholdt A, Brox JI, Reikerås O, Leivseth G (2013) Disc height and sagittal alignment in operated and non-operated levels in the lumbar spine at long-term follow-up: a case-control study. Open Orthop J 7:258–263CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Haefeli M, Kalberer F, Saegesser D, Nerlich AG, Boos N, Paesold G (2006) The course of macroscopic degeneration in the human lumbar intervertebral disc. Spine (Phila Pa 1976) 31:1522–1531CrossRef Haefeli M, Kalberer F, Saegesser D, Nerlich AG, Boos N, Paesold G (2006) The course of macroscopic degeneration in the human lumbar intervertebral disc. Spine (Phila Pa 1976) 31:1522–1531CrossRef
11.
Zurück zum Zitat Hassett G, Hart DJ, Manek NJ, Doyle DV, Spector TD (2003) Risk factors for progression of lumbar spine disc degeneration: the Chingford Study. Arthritis Rheum 48:3112–3117CrossRefPubMed Hassett G, Hart DJ, Manek NJ, Doyle DV, Spector TD (2003) Risk factors for progression of lumbar spine disc degeneration: the Chingford Study. Arthritis Rheum 48:3112–3117CrossRefPubMed
12.
Zurück zum Zitat Jarman JP, Arpinar VE, Baruah D, Klein AP, Maiman DJ, Tugan Muftuler L (2015) Intervertebral disc height loss demonstrates the threshold of major pathological changes during degeneration. Eur Spine J 24:1944–1950CrossRefPubMed Jarman JP, Arpinar VE, Baruah D, Klein AP, Maiman DJ, Tugan Muftuler L (2015) Intervertebral disc height loss demonstrates the threshold of major pathological changes during degeneration. Eur Spine J 24:1944–1950CrossRefPubMed
13.
Zurück zum Zitat Kaito T, Hosono N, Mukai Y, Makino T, Fuji T, Yonenobu K (2010) Induction of early degeneration of the adjacent segment after posterior lumbar interbody fusion by excessive distraction of lumbar disc space. J Neurosurg Spine 12:671–679CrossRefPubMed Kaito T, Hosono N, Mukai Y, Makino T, Fuji T, Yonenobu K (2010) Induction of early degeneration of the adjacent segment after posterior lumbar interbody fusion by excessive distraction of lumbar disc space. J Neurosurg Spine 12:671–679CrossRefPubMed
16.
Zurück zum Zitat Kerttula LI, Serlo WS, Tervonen OA, Pääkkö EL, Vanharanta HV (2000) Post-traumatic findings of the spine after earlier vertebral fracture in young patients: clinical and MRI study. Spine (Phila Pa 1976) 25:1104–1108CrossRef Kerttula LI, Serlo WS, Tervonen OA, Pääkkö EL, Vanharanta HV (2000) Post-traumatic findings of the spine after earlier vertebral fracture in young patients: clinical and MRI study. Spine (Phila Pa 1976) 25:1104–1108CrossRef
18.
Zurück zum Zitat Leivseth G, Braaten S, Frobin W, Brinckmann P (2006) Mobility of lumbar segments instrumented with a ProDisc II prosthesis: a two-year follow-up study. Spine (Phila Pa 1976) 31:1726–1733CrossRef Leivseth G, Braaten S, Frobin W, Brinckmann P (2006) Mobility of lumbar segments instrumented with a ProDisc II prosthesis: a two-year follow-up study. Spine (Phila Pa 1976) 31:1726–1733CrossRef
19.
Zurück zum Zitat Mannion AF, Leivseth G, Brox JI, Fritzell P, Hägg O, Fairbank JC (2014) ISSLS Prize winner: Long-term follow-up suggests spinal fusion is associated with increased adjacent segment disc degeneration but without influence on clinical outcome: results of a combined follow-up from 4 randomized controlled trials. Spine (Phila Pa 1976) 39:1373–1383CrossRef Mannion AF, Leivseth G, Brox JI, Fritzell P, Hägg O, Fairbank JC (2014) ISSLS Prize winner: Long-term follow-up suggests spinal fusion is associated with increased adjacent segment disc degeneration but without influence on clinical outcome: results of a combined follow-up from 4 randomized controlled trials. Spine (Phila Pa 1976) 39:1373–1383CrossRef
21.
Zurück zum Zitat Pfirrmann CW, Metzdorf A, Elfering A, Hodler J, Boos N (2006) Effect of aging and degeneration on disc volume and shape: a quantitative study in asymptomatic volunteers. J Orthop Res 24:1086–1094CrossRefPubMed Pfirrmann CW, Metzdorf A, Elfering A, Hodler J, Boos N (2006) Effect of aging and degeneration on disc volume and shape: a quantitative study in asymptomatic volunteers. J Orthop Res 24:1086–1094CrossRefPubMed
22.
Zurück zum Zitat Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N (2001) Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976) 26:1873–1878CrossRef Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N (2001) Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976) 26:1873–1878CrossRef
23.
Zurück zum Zitat Radcliff KE, Kepler CK, Jakoi A, Sidhu GS, Rihn J, Vaccaro AR, Albert TJ, Hilibrand AS (2013) Adjacent segment disease in the lumbar spine following different treatment interventions. Spine J 13:1339–1349CrossRefPubMed Radcliff KE, Kepler CK, Jakoi A, Sidhu GS, Rihn J, Vaccaro AR, Albert TJ, Hilibrand AS (2013) Adjacent segment disease in the lumbar spine following different treatment interventions. Spine J 13:1339–1349CrossRefPubMed
24.
Zurück zum Zitat Siepe CJ, Hitzl W, Meschede P, Sharma AK, Khattab MF, Mayer MH (2009) Interdependence between disc space height, range of motion and clinical outcome in total lumbar disc replacement. Spine (Phila Pa 1976) 34:904–916CrossRef Siepe CJ, Hitzl W, Meschede P, Sharma AK, Khattab MF, Mayer MH (2009) Interdependence between disc space height, range of motion and clinical outcome in total lumbar disc replacement. Spine (Phila Pa 1976) 34:904–916CrossRef
25.
Zurück zum Zitat Siepe CJ, Korge A, Grochulla F, Mehren C, Mayer HM (2008) Analysis of post-operative pain patterns following total lumbar disc replacement: results from fluoroscopically guided spine infiltrations. Eur Spine J 17:44–56CrossRefPubMed Siepe CJ, Korge A, Grochulla F, Mehren C, Mayer HM (2008) Analysis of post-operative pain patterns following total lumbar disc replacement: results from fluoroscopically guided spine infiltrations. Eur Spine J 17:44–56CrossRefPubMed
26.
Zurück zum Zitat Siepe CJ, Mayer HM, Heinz-Leisenheimer M, Korge A (2007) Total lumbar disc replacement: different results for different levels. Spine (Phila Pa 1976) 32:782–790CrossRef Siepe CJ, Mayer HM, Heinz-Leisenheimer M, Korge A (2007) Total lumbar disc replacement: different results for different levels. Spine (Phila Pa 1976) 32:782–790CrossRef
27.
Zurück zum Zitat Strube P, Hoff EK, Schürings M, Schmidt H, Dreischarf M, Rohlmann A, Putzier M (2013) Parameters influencing the outcome after total disc replacement at the lumbosacral junction. Part 2: distraction and posterior translation lead to clinical failure after a mean follow-up of 5 years. Eur Spine J 22:2279–2287CrossRefPubMedPubMedCentral Strube P, Hoff EK, Schürings M, Schmidt H, Dreischarf M, Rohlmann A, Putzier M (2013) Parameters influencing the outcome after total disc replacement at the lumbosacral junction. Part 2: distraction and posterior translation lead to clinical failure after a mean follow-up of 5 years. Eur Spine J 22:2279–2287CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Minamide A, Oka H, Ishimoto Y, Nagata K, Kagotani R, Takiguchi N, Akune T, Kawaguchi H, Nakamura K, Yoshida M (2014) Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study. Osteoarthr Cartil 22:104–110. https://doi.org/10.1016/j.joca.2013.10.019 CrossRefPubMed Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Minamide A, Oka H, Ishimoto Y, Nagata K, Kagotani R, Takiguchi N, Akune T, Kawaguchi H, Nakamura K, Yoshida M (2014) Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study. Osteoarthr Cartil 22:104–110. https://​doi.​org/​10.​1016/​j.​joca.​2013.​10.​019 CrossRefPubMed
29.
Zurück zum Zitat Videman T, Battié MC, Parent E, Gibbons LE, Vainio P, Kaprio J (2008) Progression and determinants of quantitative magnetic resonance imaging measures of lumbar disc degeneration: a five-year follow-up of adult male monozygotic twins. Spine (Phila Pa 1976) 33:1484–1490CrossRef Videman T, Battié MC, Parent E, Gibbons LE, Vainio P, Kaprio J (2008) Progression and determinants of quantitative magnetic resonance imaging measures of lumbar disc degeneration: a five-year follow-up of adult male monozygotic twins. Spine (Phila Pa 1976) 33:1484–1490CrossRef
30.
Zurück zum Zitat Wang H, Chen W, Jiang J, Lu F, Ma X, Xia X (2016) Analysis of the correlative factors in the selection of interbody fusion cage height in transforaminal lumbar interbody fusion. BMC Musculoskelet Disord 17:9CrossRefPubMedPubMedCentral Wang H, Chen W, Jiang J, Lu F, Ma X, Xia X (2016) Analysis of the correlative factors in the selection of interbody fusion cage height in transforaminal lumbar interbody fusion. BMC Musculoskelet Disord 17:9CrossRefPubMedPubMedCentral
Metadaten
Titel
Magnetic resonance morphometry of the adult normal lumbar intervertebral space
verfasst von
Apostolos H. Fyllos
Dimitrios L. Arvanitis
Apostolos H. Karantanas
Sokratis E. Varitimidis
Michael Hantes
Aristeidis H. Zibis
Publikationsdatum
06.06.2018
Verlag
Springer Paris
Erschienen in
Surgical and Radiologic Anatomy / Ausgabe 9/2018
Print ISSN: 0930-1038
Elektronische ISSN: 1279-8517
DOI
https://doi.org/10.1007/s00276-018-2048-7

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