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01.11.2015 | Head and Neck

Perfusion imaging of parotid gland tumours: usefulness of arterial spin labeling for differentiating Warthin’s tumours

verfasst von: Hiroki Kato, Masayuki Kanematsu, Haruo Watanabe, Kimihiro Kajita, Keisuke Mizuta, Mitsuhiro Aoki, Tomoyuki Okuaki

Erschienen in: European Radiology | Ausgabe 11/2015

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Abstract

Objective

To assess prospectively the efficacy of arterial spin labelling (ASL) against conventional and diffusion-weighted (DW) MR imaging for differentiating parotid gland tumours.

Methods

We included 10 pleomorphic adenomas, 12 Warthin's tumours, and nine malignant tumours of the parotid glands. Only tumours larger than 10 mm were included in this study. All parotid gland tumours underwent T1-weighted, T2-weighted, DW, and ASL imaging. Tumour-to-parotid gland signal intensity ratios (SIRs) and apparent diffusion coefficients (ADCs) of solid components were correlated with these pathologies.

Results

SIRs on T2-weighted images and ADCs were higher in pleomorphic adenomas than in Warthin's tumours (p < .01) and malignant tumours (p < .01). SIRs on ASL were higher in Warthin's tumours than in pleomorphic adenomas (p < .01) and malignant tumours (p < .05). Az value of SIRs on ASL for differentiating Warthin's tumours from the other pathologies was 0.982. The sensitivity, specificity, and accuracy of SIRs on ASL for the diagnosis of Warthin's tumours at an optimal SIR threshold of over 8.70 were 91.7 %, 94.7 %, and 93.5 %, respectively.

Conclusions

ASL with SIR measurements could non-invasively evaluate tumour blood flow of parotid gland tumours and differentiate Warthin's tumours from pleomorphic adenomas and malignant tumours.

Key Points

• ASL non-invasively evaluates tumour blood flow of parotid gland tumours

• ASL differentiates Warthin's tumours from pleomorphic adenomas and malignant tumours

• ASL cannot differentiate between pleomorphic adenomas and malignant tumours

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Titel: Perfusion imaging of parotid gland tumours: usefulness of arterial spin labeling for differentiating Warthin’s tumours
verfasst von: Hiroki Kato
Masayuki Kanematsu
Haruo Watanabe
Kimihiro Kajita
Keisuke Mizuta
Mitsuhiro Aoki
Tomoyuki Okuaki
Publikationsdatum: 01.11.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 11/2015
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-3755-7

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Perfusion imaging of parotid gland tumours: usefulness of arterial spin labeling for differentiating Warthin’s tumours