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23.08.2016 | Oncology

Diagnostic performance of MR imaging findings and quantitative values in the differentiation of seromucinous borderline tumour from endometriosis-related malignant ovarian tumour

verfasst von: Yasuhisa Kurata, Aki Kido, Yusaku Moribata, Kyoko Kameyama, Yuki Himoto, Sachiko Minamiguchi, Ikuo Konishi, Kaori Togashi

Erschienen in: European Radiology | Ausgabe 4/2017

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Abstract

Objectives

To evaluate the diagnostic performance of quantitative values and MRI findings for differentiating seromucinous borderline tumours (SMBTs) from endometriosis-related malignant ovarian tumours (MT).

Methods

This retrospective study examined 19 lesions from SMBT and 84 lesions from MT. The following quantitative values were evaluated using receiver-operating characteristic analysis: overall and solid portion sizes, fluid signal intensity (SI), degree of contrast-enhancement, and mean and minimum apparent diffusion coefficient (ADC) values of the solid portion. Two radiologists independently evaluated four MRI findings characteristic of SMBT, fluid SI on the T1-weighted image and SI of the solid portion on diffusion-weighted image. The diagnostic values of these findings and interobserver agreement were assessed.

Results

For diagnosing SMBT, the mean ADC value of the solid portion showed the greatest area under the curve (0.860) (cut-off value: 1.31 × 10^-3 mm²/s, sensitivity: 1.00, specificity: 0.61). The T2-weighted image (T2WI) high SI solid portion was the most useful finding, with high specificity and interobserver agreement (sensitivity, 0.58; specificity, 0.95–0.96, kappa = 0.96), followed by T2WI low SI core (sensitivity, 0.48–0.63; specificity, 0.98, kappa = 0.68).

Conclusion

Mean ADC values of the solid portion, T2WI high SI solid portion, and T2WI low SI core were useful for differentiating SMBT from MT.

Key Points

• SMBT is a newly categorised ovarian tumour often associated with endometriosis.

• Differentiation of SMBT from endometriosis-related malignant ovarian tumour is clinically important.

• Diagnostic performances of quantitative values and MRI findings were evaluated.

• Mean ADC value of the solid portion was the most useful value.

• “T2WI high SI solid portion” was the most useful MRI finding.

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Titel: Diagnostic performance of MR imaging findings and quantitative values in the differentiation of seromucinous borderline tumour from endometriosis-related malignant ovarian tumour
verfasst von: Yasuhisa Kurata
Aki Kido
Yusaku Moribata
Kyoko Kameyama
Yuki Himoto
Sachiko Minamiguchi
Ikuo Konishi
Kaori Togashi
Publikationsdatum: 23.08.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 4/2017
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-016-4533-x

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Diagnostic performance of MR imaging findings and quantitative values in the differentiation of seromucinous borderline tumour from endometriosis-related malignant ovarian tumour