Skip to main content
Erschienen in: International Journal of Colorectal Disease 1/2013

01.01.2013 | Original Article

Fast-track colorectal surgery: protocol adherence influences postoperative outcomes

verfasst von: Francesco Feroci, Elisa Lenzi, Maddalena Baraghini, Alessia Garzi, Andrea Vannucchi, Stefano Cantafio, Marco Scatizzi

Erschienen in: International Journal of Colorectal Disease | Ausgabe 1/2013

Einloggen, um Zugang zu erhalten

Abstract

Purpose

This single-center prospective cohort study, conducted outside of a clinical trial, tried to identify the importance of each fast-track surgery procedure and protocol adherence level on clinical outcomes after colorectal surgery.

Methods

From a prospectively maintained database, 606 patients who underwent elective laparoscopic or open colorectal resection within a well established fast-track surgery (FT) protocol, between 2005 and 2011, were identified. Univariate and multivariate analysis were performed to assess the relationship between each FT procedure with an adherence rate <100 % and the outcome variables (length of stay—LOS, 30-day morbidity and readmission rate). Patients were divided into four adherence level groups to FT procedures—100 %, 85–95 %,70–80 %, and <65 %. Each adherence group was compared with the other groups to evaluate differences in clinical outcome variables.

Results

Group comparisons revealed that higher levels of FT protocol adherence corresponded to significantly improved LOS and morbidity rates. Readmission rates were only significantly different between the full fast-track pathway and the less implemented groups. Multivariate analyses revealed that the fast removal of bladder catheter positively influenced length of stay (p < 0.0001) and 30-day morbidity (p < 0.0001). Laparoscopy surgery, no drain positioning and enforced mobilization improved LOS (p = 0.027, p < 0.0001, p = 0.002, respectively). Early solid feeding improved LOS (p < 0.0001), morbidity (p < 0.0001) and readmission rate (p = 0.011).

Conclusion

Postoperative outcomes after colorectal surgery are directly proportional to FT protocol adherence. The early removal of the bladder catheter and early postoperative solid feeding independently influenced the length of hospital stay and 30-day morbidity rates.
Literatur
1.
Zurück zum Zitat Slim K (2011) Fast-track surgery: the next revolution in surgical care following laparoscopy. Colorectal Dis 13(5):478–480PubMedCrossRef Slim K (2011) Fast-track surgery: the next revolution in surgical care following laparoscopy. Colorectal Dis 13(5):478–480PubMedCrossRef
2.
Zurück zum Zitat Lassen K, Soop M, Nygren J, Cox PB, Hendry PO, Spies C, von Meyenfeldt MF, Fearon KC, Revhaug A, Norderval S, Ljungqvist O, Lobo DN, Dejong CH, Enhanced Recovery After Surgery (ERAS) Group (2009) Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations. Arch Surg 144(10):961–969PubMedCrossRef Lassen K, Soop M, Nygren J, Cox PB, Hendry PO, Spies C, von Meyenfeldt MF, Fearon KC, Revhaug A, Norderval S, Ljungqvist O, Lobo DN, Dejong CH, Enhanced Recovery After Surgery (ERAS) Group (2009) Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations. Arch Surg 144(10):961–969PubMedCrossRef
3.
Zurück zum Zitat Raue W, Haase O, Junghans T, Scharfenberg M, Muller JM, Schwenk W (2004) ‘Fast-track’ multimodal rehabilitation program improves outcome after laparoscopic sigmoidectomy: a controlled prospective evaluation. Surg Endosc 18:1463–8.45PubMedCrossRef Raue W, Haase O, Junghans T, Scharfenberg M, Muller JM, Schwenk W (2004) ‘Fast-track’ multimodal rehabilitation program improves outcome after laparoscopic sigmoidectomy: a controlled prospective evaluation. Surg Endosc 18:1463–8.45PubMedCrossRef
4.
Zurück zum Zitat Basse L, Jakobsen DH, Bardram (2005) Functional recovery after open versus laparoscopic colonic resection: a randomized, blinded study. Ann Surg 241:416–423PubMedCrossRef Basse L, Jakobsen DH, Bardram (2005) Functional recovery after open versus laparoscopic colonic resection: a randomized, blinded study. Ann Surg 241:416–423PubMedCrossRef
5.
Zurück zum Zitat King PM, Blazeby JM, Ewings P (2006) The influence of an enhanced recovery programme on clinical outcomes, costs and quality of life after surgery for colorectal cancer. Colorectal Dis 8:506–513PubMedCrossRef King PM, Blazeby JM, Ewings P (2006) The influence of an enhanced recovery programme on clinical outcomes, costs and quality of life after surgery for colorectal cancer. Colorectal Dis 8:506–513PubMedCrossRef
6.
Zurück zum Zitat Basse L, Thorbol JE, Lossl K, Kehlet H (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277PubMedCrossRef Basse L, Thorbol JE, Lossl K, Kehlet H (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277PubMedCrossRef
7.
Zurück zum Zitat Gatt M, Anderson AD, Reddy BS, Hayward-Sampson P, Tring IC, MacFie J (2005) Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg 92:1354–1362PubMedCrossRef Gatt M, Anderson AD, Reddy BS, Hayward-Sampson P, Tring IC, MacFie J (2005) Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg 92:1354–1362PubMedCrossRef
8.
Zurück zum Zitat Khoo CK, Vickery CJ, Forsyth N, Vinall NS, Eyre-Brook IA (2007) A prospective randomized controlled trial of multimodal perioperative management protocol in patients undergoing elective colorectal resection for cancer. Ann Surg 245:867–872PubMedCrossRef Khoo CK, Vickery CJ, Forsyth N, Vinall NS, Eyre-Brook IA (2007) A prospective randomized controlled trial of multimodal perioperative management protocol in patients undergoing elective colorectal resection for cancer. Ann Surg 245:867–872PubMedCrossRef
9.
Zurück zum Zitat Muller S, Zalunardo MP, Hubner M, Clavien PA, Demartines N (2009) A fast-track program reduces complications and length of hospital stay after open colonic surgery. Gastroenterology 136:842–847PubMedCrossRef Muller S, Zalunardo MP, Hubner M, Clavien PA, Demartines N (2009) A fast-track program reduces complications and length of hospital stay after open colonic surgery. Gastroenterology 136:842–847PubMedCrossRef
10.
Zurück zum Zitat Serclova Z, Dytrych P, Marvan J et al (2009) Fast-track in open intestinal surgery: prospective randomized study (Clinical Trials Gov Identifier no. NCT00123456). Clin Nutr 28:618–624PubMedCrossRef Serclova Z, Dytrych P, Marvan J et al (2009) Fast-track in open intestinal surgery: prospective randomized study (Clinical Trials Gov Identifier no. NCT00123456). Clin Nutr 28:618–624PubMedCrossRef
11.
Zurück zum Zitat Delaney CP, Zutshi M, Senagore AJ, Remzi FH, Hammel J, Fazio VW (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859PubMedCrossRef Delaney CP, Zutshi M, Senagore AJ, Remzi FH, Hammel J, Fazio VW (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859PubMedCrossRef
12.
Zurück zum Zitat Anderson AD, McNaught CE, MacFie J, Tring I, Barker P, Mitchell CJ (2003) Randomized clinical trial of multimodal optimization and standard perioperative surgical care. Br J Surg 90:1497–1504PubMedCrossRef Anderson AD, McNaught CE, MacFie J, Tring I, Barker P, Mitchell CJ (2003) Randomized clinical trial of multimodal optimization and standard perioperative surgical care. Br J Surg 90:1497–1504PubMedCrossRef
13.
Zurück zum Zitat Spanjersberg WR, Reurings J, Keus F, van Laarhoven CJ (2011) Fast track surgery versus conventional recovery strategies for colorectal surgery. Cochrane Database Syst Rev. Feb 16(2): Spanjersberg WR, Reurings J, Keus F, van Laarhoven CJ (2011) Fast track surgery versus conventional recovery strategies for colorectal surgery. Cochrane Database Syst Rev. Feb 16(2):
14.
Zurück zum Zitat Maessen J, Dejong CH, Hausel J, Nygren J, Lassen K, Anderson J (2007) A protocol is not enough to implement an enhanced recovery programme for colorectal resection. Br J Surg 94:224–231PubMedCrossRef Maessen J, Dejong CH, Hausel J, Nygren J, Lassen K, Anderson J (2007) A protocol is not enough to implement an enhanced recovery programme for colorectal resection. Br J Surg 94:224–231PubMedCrossRef
15.
Zurück zum Zitat Ahmed J, Khan S, Gatt M, Kallam R, MacFie J (2010) Compliance with enhanced recovery programmes in elective colorectal surgery. Br J Surg 97(5):754–758PubMedCrossRef Ahmed J, Khan S, Gatt M, Kallam R, MacFie J (2010) Compliance with enhanced recovery programmes in elective colorectal surgery. Br J Surg 97(5):754–758PubMedCrossRef
16.
Zurück zum Zitat Lassen K, Hannemann P, Ljungqvist O, Fearon K, Dejong CH, von Meyenfeldt MF, Hausel J, Nygren J, Andersen J, Revhaug A, Enhanced Recovery After Surgery Group (2005) Patterns in current perioperative practice: survey of colorectal surgeons in five northern European countries. BMJ 330(7505):1420–1421PubMedCrossRef Lassen K, Hannemann P, Ljungqvist O, Fearon K, Dejong CH, von Meyenfeldt MF, Hausel J, Nygren J, Andersen J, Revhaug A, Enhanced Recovery After Surgery Group (2005) Patterns in current perioperative practice: survey of colorectal surgeons in five northern European countries. BMJ 330(7505):1420–1421PubMedCrossRef
17.
Zurück zum Zitat Fearon KC, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CH, Lassen K, Nygren J, Hausel J, Soop M, Andersen J, Kehlet H (2005) Enhanced recovery aftersurgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24(3):466–477PubMedCrossRef Fearon KC, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CH, Lassen K, Nygren J, Hausel J, Soop M, Andersen J, Kehlet H (2005) Enhanced recovery aftersurgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24(3):466–477PubMedCrossRef
18.
Zurück zum Zitat Feroci F, Kröning KC, Lenzi E, Moraldi L, Cantafio S, Scatizzi M (2011) Laparoscopy within a fast-track program enhances the short-term results after elective surgery for resectable colorectal cancer. Surg Endosc 25(9):2919–2925PubMedCrossRef Feroci F, Kröning KC, Lenzi E, Moraldi L, Cantafio S, Scatizzi M (2011) Laparoscopy within a fast-track program enhances the short-term results after elective surgery for resectable colorectal cancer. Surg Endosc 25(9):2919–2925PubMedCrossRef
19.
Zurück zum Zitat Scatizzi M, Kröning KC, Boddi V, De Prizio M, Feroci F (2010) Fast-track surgery after laparoscopic colorectal surgery: is it feasible in a general surgery unit? Surgery 147(2):219–226PubMedCrossRef Scatizzi M, Kröning KC, Boddi V, De Prizio M, Feroci F (2010) Fast-track surgery after laparoscopic colorectal surgery: is it feasible in a general surgery unit? Surgery 147(2):219–226PubMedCrossRef
20.
Zurück zum Zitat Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J, Enhanced Recovery After Surgery Study Group (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146(5):571–577PubMedCrossRef Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J, Enhanced Recovery After Surgery Study Group (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146(5):571–577PubMedCrossRef
21.
Zurück zum Zitat Vlug MS, Wind J, Wind J, van der Zaag E, Ubbink DT, Cense HA, Bemelman WA (2009) Systematic review of laparoscopic versus open colonic surgery within an enhanced recovery programme. Colorectal Dis 11:335–343PubMedCrossRef Vlug MS, Wind J, Wind J, van der Zaag E, Ubbink DT, Cense HA, Bemelman WA (2009) Systematic review of laparoscopic versus open colonic surgery within an enhanced recovery programme. Colorectal Dis 11:335–343PubMedCrossRef
22.
Zurück zum Zitat Polle SW, Wind J, Fuhring JW, Hofland J, Gouma DJ, Bemelman WA (2007) Implementation of a fast-track perioperative care program: what are the difficulties? Dig Surg 24:441–449PubMedCrossRef Polle SW, Wind J, Fuhring JW, Hofland J, Gouma DJ, Bemelman WA (2007) Implementation of a fast-track perioperative care program: what are the difficulties? Dig Surg 24:441–449PubMedCrossRef
23.
Zurück zum Zitat Soop M, Nygren J, Ljungqvist O (2006) Optimizing perioperative management of patients undergoing colorectal surgery: what is new? Curr Opin Crit Care 12:166–170PubMedCrossRef Soop M, Nygren J, Ljungqvist O (2006) Optimizing perioperative management of patients undergoing colorectal surgery: what is new? Curr Opin Crit Care 12:166–170PubMedCrossRef
24.
Zurück zum Zitat Walter CJ, Smith A, Guillou P (2006) Perceptions of the application of fast-track surgical principles by generalsurgeons. Ann R Coll Surg Engl 88:191–195PubMedCrossRef Walter CJ, Smith A, Guillou P (2006) Perceptions of the application of fast-track surgical principles by generalsurgeons. Ann R Coll Surg Engl 88:191–195PubMedCrossRef
25.
Zurück zum Zitat Kahokehr A, Sammour T, Zargar-Shoshtari K, Thompson LG, Hill AG (2009) Implementation of ERAS and how to overcome the barriers. Int J Surg 7:16–19PubMedCrossRef Kahokehr A, Sammour T, Zargar-Shoshtari K, Thompson LG, Hill AG (2009) Implementation of ERAS and how to overcome the barriers. Int J Surg 7:16–19PubMedCrossRef
26.
Zurück zum Zitat Hendry PO, Hausel J, Nygren J, Lassen K, Dejong CH, Ljungqvist O, Fearon KC, Enhanced Recovery After Surgery Study Group (2009) Determinants of outcome after colorectal resection within an enhanced recovery programme. Br J Surg 96(2):197–205PubMedCrossRef Hendry PO, Hausel J, Nygren J, Lassen K, Dejong CH, Ljungqvist O, Fearon KC, Enhanced Recovery After Surgery Study Group (2009) Determinants of outcome after colorectal resection within an enhanced recovery programme. Br J Surg 96(2):197–205PubMedCrossRef
27.
Zurück zum Zitat Adamina M, Kehlet H, Tomlinson GA, Senagore AJ, Delaney CP (2011) Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery. Surgery 149(6):830–840PubMedCrossRef Adamina M, Kehlet H, Tomlinson GA, Senagore AJ, Delaney CP (2011) Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery. Surgery 149(6):830–840PubMedCrossRef
28.
Zurück zum Zitat Vlug MS, Wind J, Hollmann MW, Ubbink DT, Cense HA, Engel AF, Gerhards MF, van Wagensveld BA, van der Zaag ES, van Geloven AA, Sprangers MA, Cuesta MA, Bemelman WA, LAFA study group (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical Trial (LAFA-study). Ann Surg 254(6):868–875PubMedCrossRef Vlug MS, Wind J, Hollmann MW, Ubbink DT, Cense HA, Engel AF, Gerhards MF, van Wagensveld BA, van der Zaag ES, van Geloven AA, Sprangers MA, Cuesta MA, Bemelman WA, LAFA study group (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical Trial (LAFA-study). Ann Surg 254(6):868–875PubMedCrossRef
29.
Zurück zum Zitat Basse L, Werner M, Kehlet H (2000) Is urinary drainage necessary during continuous epidural analgesia after colonic resection? Reg Anesth Pain Med 25(5):498–501PubMed Basse L, Werner M, Kehlet H (2000) Is urinary drainage necessary during continuous epidural analgesia after colonic resection? Reg Anesth Pain Med 25(5):498–501PubMed
30.
Zurück zum Zitat Andersen HK, Lewis SJ, Thomas S (2006) Early enteral nutrition within 24 h of colorectal surgery versus later commencement of feeding for postoperative complications. Cochrane Database Syst Rev. CD004080 Andersen HK, Lewis SJ, Thomas S (2006) Early enteral nutrition within 24 h of colorectal surgery versus later commencement of feeding for postoperative complications. Cochrane Database Syst Rev. CD004080
Metadaten
Titel
Fast-track colorectal surgery: protocol adherence influences postoperative outcomes
verfasst von
Francesco Feroci
Elisa Lenzi
Maddalena Baraghini
Alessia Garzi
Andrea Vannucchi
Stefano Cantafio
Marco Scatizzi
Publikationsdatum
01.01.2013
Verlag
Springer-Verlag
Erschienen in
International Journal of Colorectal Disease / Ausgabe 1/2013
Print ISSN: 0179-1958
Elektronische ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-012-1569-5

Weitere Artikel der Ausgabe 1/2013

International Journal of Colorectal Disease 1/2013 Zur Ausgabe

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Was nützt die Kraniektomie bei schwerer tiefer Hirnblutung?

17.05.2024 Hirnblutung Nachrichten

Eine Studie zum Nutzen der druckentlastenden Kraniektomie nach schwerer tiefer supratentorieller Hirnblutung deutet einen Nutzen der Operation an. Für überlebende Patienten ist das dennoch nur eine bedingt gute Nachricht.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.