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Erschienen in: Surgical Endoscopy 6/2013

01.06.2013

Real-time near-infrared (NIR) fluorescent cholangiography in single-site robotic cholecystectomy (SSRC): a single-institutional prospective study

verfasst von: Giuseppe Spinoglio, Fabio Priora, Paolo Pietro Bianchi, Francesco Saverio Lucido, Alessio Licciardello, Valeria Maglione, Federica Grosso, Raul Quarati, Ferruccio Ravazzoni, Luca Matteo Lenti

Erschienen in: Surgical Endoscopy | Ausgabe 6/2013

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Abstract

Background

Bile duct injury is a rare but serious complication of laparoscopic cholecystectomy and the primary cause is misinterpretation of biliary anatomy. This may occur more frequently with a single-incision approach due to difficulties in exposing and visualizing the triangle of Calot. Intraoperative cholangiography was proposed to overcome this problem, but due to multiple issues, it is not used routinely. Indocyanine green (ICG) near-infrared (NIR) fluorescent cholangiography is non invasive and provides real-time biliary images during surgery, which may improve the safety of single-incision cholecystectomy. This study aims to evaluate the efficacy and safety of this technique during single-site robotic cholecystectomy (SSRC).

Methods

Patients presenting with symptomatic biliary gallstones without suspicion of common bile duct stones underwent SSRC with ICG-NIR fluorescent cholangiography using the da Vinci Fluorescence Imaging Vision System. During patient preparation, 2.5 mg of ICG was injected intravenously. During surgery, the biliary anatomy was imaged in real time, which guided dissection of Calot’s triangle. Perioperative outcomes included biliary tree visualizations, operative time, conversion and complications rates, and length of hospital stay.

Results

There were 45 cases between July 2011 and January 2012. All procedures were completed successfully; there were no conversions and at least one structure was visualized in each patient. The rates of visualization were 93 % for the cystic duct, 88 % for the common hepatic duct, and 91 % for the common bile duct prior to Calot’s dissection; after Calot’s dissection, the rates were 97 % for all three ducts. Mean hospital stay was 1.1 days and there were no bile duct injuries or any other major complications.

Conclusion

Real-time high-resolution fluorescent imaging to identify the biliary tree anatomy during SSRC using the da Vinci Fluorescence Imaging Vision System was safe and effective.
Literatur
1.
Zurück zum Zitat Adamsen S, Hansen OH, Funch-Jensen P, Schulze S, Stage JG, Wara P (1997) Bile duct injury during laparoscopic cholecystectomy: a prospective nationwide series. J Am Coll Surg 184:571–578PubMed Adamsen S, Hansen OH, Funch-Jensen P, Schulze S, Stage JG, Wara P (1997) Bile duct injury during laparoscopic cholecystectomy: a prospective nationwide series. J Am Coll Surg 184:571–578PubMed
2.
Zurück zum Zitat Flum DR, Cheadle A, Prela C, Dellinger EP, Chan L (2003) Bile duct injury during cholecystectomy and survival in medicare beneficiaries. JAMA 290:2168–2173PubMedCrossRef Flum DR, Cheadle A, Prela C, Dellinger EP, Chan L (2003) Bile duct injury during cholecystectomy and survival in medicare beneficiaries. JAMA 290:2168–2173PubMedCrossRef
3.
Zurück zum Zitat Strasberg SM, Hertl M, Soper NJ (1995) An analysis of the problem of biliary injury during laparoscopic cholecystectomy. J Am Coll Surg 180:101–125PubMed Strasberg SM, Hertl M, Soper NJ (1995) An analysis of the problem of biliary injury during laparoscopic cholecystectomy. J Am Coll Surg 180:101–125PubMed
4.
Zurück zum Zitat Dolan JP, Diggs BS, Sheppard BC, Hunter JG (2005) 10-year trend in the national volume of bile duct injuries requiring operative repair. Surg Endosc 19:967–973PubMedCrossRef Dolan JP, Diggs BS, Sheppard BC, Hunter JG (2005) 10-year trend in the national volume of bile duct injuries requiring operative repair. Surg Endosc 19:967–973PubMedCrossRef
5.
Zurück zum Zitat Connor S, Garden OJ (2006) Bile duct injury in the era of laparoscopic cholecystectomy. Br J Surg 93:158–168PubMedCrossRef Connor S, Garden OJ (2006) Bile duct injury in the era of laparoscopic cholecystectomy. Br J Surg 93:158–168PubMedCrossRef
6.
Zurück zum Zitat de Reuver PR, Sprangers MA, Rauws EA, Lameris JS, Busch OR, van Gulik TM, Gouma DJ (2008) Impact of bile duct injury after laparoscopic cholecystectomy on quality of life: a longitudinal study after multidisciplinary treatment. Endoscopy 40(8):637–643PubMedCrossRef de Reuver PR, Sprangers MA, Rauws EA, Lameris JS, Busch OR, van Gulik TM, Gouma DJ (2008) Impact of bile duct injury after laparoscopic cholecystectomy on quality of life: a longitudinal study after multidisciplinary treatment. Endoscopy 40(8):637–643PubMedCrossRef
7.
Zurück zum Zitat Kern KA (1997) Malpractice litigation involving laparoscopic cholecystectomy. Cost, cause, and consequences. Arch Surg 132(4):392–397PubMedCrossRef Kern KA (1997) Malpractice litigation involving laparoscopic cholecystectomy. Cost, cause, and consequences. Arch Surg 132(4):392–397PubMedCrossRef
8.
Zurück zum Zitat McLean TR (2005) Monetary lessons from litigation involving laparoscopic cholecystectomy. Am Surg 71(7):606–612PubMed McLean TR (2005) Monetary lessons from litigation involving laparoscopic cholecystectomy. Am Surg 71(7):606–612PubMed
9.
Zurück zum Zitat Scurr JR, Brigstocke JR, Shields DA, Scurr JH (2010) Medicolegal claims following laparoscopic cholecystectomy in the UK and Ireland. Ann R Coll Surg Engl 92(4):286–291PubMedCrossRef Scurr JR, Brigstocke JR, Shields DA, Scurr JH (2010) Medicolegal claims following laparoscopic cholecystectomy in the UK and Ireland. Ann R Coll Surg Engl 92(4):286–291PubMedCrossRef
10.
Zurück zum Zitat Gossage JA, Forshaw MJ (2010) Prevalence and outcome of litigation claims in England after laparoscopic cholecystectomy. Int J Clin Pract 64(13):1832–1835PubMedCrossRef Gossage JA, Forshaw MJ (2010) Prevalence and outcome of litigation claims in England after laparoscopic cholecystectomy. Int J Clin Pract 64(13):1832–1835PubMedCrossRef
11.
Zurück zum Zitat Nuzzo G, Giuliante F, Giovannini I, Ardito F, D’Acapito F, Vellone M, Murazio M, Capelli G (2005) Bile duct injury during laparoscopic cholecystectomy: results of an Italian national survey on 56 591 cholecystectomies. Arch Surg 140:986–992PubMedCrossRef Nuzzo G, Giuliante F, Giovannini I, Ardito F, D’Acapito F, Vellone M, Murazio M, Capelli G (2005) Bile duct injury during laparoscopic cholecystectomy: results of an Italian national survey on 56 591 cholecystectomies. Arch Surg 140:986–992PubMedCrossRef
12.
Zurück zum Zitat Way LW, Stewart L, Gantert W, Liu K, Lee CM, Whang K, Hunter JG (2003) Causes and prevention of laparoscopic bile duct injuries: analysis of 252 cases from a human factors and cognitive psychology perspective. Ann Surg 237:460–469PubMed Way LW, Stewart L, Gantert W, Liu K, Lee CM, Whang K, Hunter JG (2003) Causes and prevention of laparoscopic bile duct injuries: analysis of 252 cases from a human factors and cognitive psychology perspective. Ann Surg 237:460–469PubMed
13.
Zurück zum Zitat Wu YV, Linehan DC (2010) Bile duct injuries in the era of laparoscopic cholecystectomies. Surg Clin North Am 90(4):787–802PubMedCrossRef Wu YV, Linehan DC (2010) Bile duct injuries in the era of laparoscopic cholecystectomies. Surg Clin North Am 90(4):787–802PubMedCrossRef
14.
Zurück zum Zitat MacFadyen BV (2006) Intraoperative cholangiography: past, present, and future. Surg Endosc 20(Suppl 2):S436–S440PubMedCrossRef MacFadyen BV (2006) Intraoperative cholangiography: past, present, and future. Surg Endosc 20(Suppl 2):S436–S440PubMedCrossRef
15.
Zurück zum Zitat Connor S, Garden OJ (2006) Bile duct injury in the era of laparoscopic cholecystectomy. Br J Surg 93(2):158–168PubMedCrossRef Connor S, Garden OJ (2006) Bile duct injury in the era of laparoscopic cholecystectomy. Br J Surg 93(2):158–168PubMedCrossRef
16.
Zurück zum Zitat Yousefpour Azary S, Kalbasi H, Setayesh A, Mousavi M, Hashemi A, Khodadoostan M, Zali MR, Mohammad Alizadeh AH (2011) Predictive value and main determinants of abnormal features of intraoperative cholangiography during cholecystectomy. Hepatobiliary Pancreat Dis Int 10(3):308–312PubMedCrossRef Yousefpour Azary S, Kalbasi H, Setayesh A, Mousavi M, Hashemi A, Khodadoostan M, Zali MR, Mohammad Alizadeh AH (2011) Predictive value and main determinants of abnormal features of intraoperative cholangiography during cholecystectomy. Hepatobiliary Pancreat Dis Int 10(3):308–312PubMedCrossRef
17.
Zurück zum Zitat Yeo D, Mackay S, Martin D (2012) Single-incision laparoscopic cholecystectomy with routine intraoperative cholangiography and common bile duct exploration via the umbilical port. Surg Endosc 26(4):1122–1127PubMedCrossRef Yeo D, Mackay S, Martin D (2012) Single-incision laparoscopic cholecystectomy with routine intraoperative cholangiography and common bile duct exploration via the umbilical port. Surg Endosc 26(4):1122–1127PubMedCrossRef
18.
Zurück zum Zitat Ford JA, Soop M, Du J, Loveday BP, Rodgers M (2012) Systematic review of intraoperative cholangiography in cholecystectomy. Br J Surg 99(2):160–167PubMedCrossRef Ford JA, Soop M, Du J, Loveday BP, Rodgers M (2012) Systematic review of intraoperative cholangiography in cholecystectomy. Br J Surg 99(2):160–167PubMedCrossRef
19.
Zurück zum Zitat Flum DR, Dellinger EP, Cheadle A, Chan L, Koepsell T (2003) Intraoperative cholangiography and risk of common bile duct injury during cholecystectomy. JAMA 289(13):1639–1644PubMedCrossRef Flum DR, Dellinger EP, Cheadle A, Chan L, Koepsell T (2003) Intraoperative cholangiography and risk of common bile duct injury during cholecystectomy. JAMA 289(13):1639–1644PubMedCrossRef
20.
21.
Zurück zum Zitat Ladocsi LT, Benitez LD, Filippone DR, Nance FC (1997) Intraoperative cholangiography in laparoscopic cholecystectomy: a review of 734 consecutive cases. Am Surg 63(2):150–156PubMed Ladocsi LT, Benitez LD, Filippone DR, Nance FC (1997) Intraoperative cholangiography in laparoscopic cholecystectomy: a review of 734 consecutive cases. Am Surg 63(2):150–156PubMed
22.
Zurück zum Zitat Corsale I, Ruggiero R, Mandato M, Zenone P, De Martino A, Ripa C, Perrotta S, Guida A, Procaccini F, Procaccini E (2002) Intraoperative cholangiography in videolaparoscopic cholecystectomy: indications, advantages, and limitations. G Chir 23(6–7):269–273PubMed Corsale I, Ruggiero R, Mandato M, Zenone P, De Martino A, Ripa C, Perrotta S, Guida A, Procaccini F, Procaccini E (2002) Intraoperative cholangiography in videolaparoscopic cholecystectomy: indications, advantages, and limitations. G Chir 23(6–7):269–273PubMed
23.
Zurück zum Zitat Piacentini F, Perri S, Pietrangeli F, Nardi M Jr., Dalla Torre A, Nicita A, Lotti R, Castaldo P, Gabbrielli F, Castiglia D, Citone G (2003) Intraoperative cholangiography during laparoscopic cholecystectomy: selective or routine? G Chir 24:123–128PubMed Piacentini F, Perri S, Pietrangeli F, Nardi M Jr., Dalla Torre A, Nicita A, Lotti R, Castaldo P, Gabbrielli F, Castiglia D, Citone G (2003) Intraoperative cholangiography during laparoscopic cholecystectomy: selective or routine? G Chir 24:123–128PubMed
24.
Zurück zum Zitat Karthikesalingam A, Markar SR, Weerakkody R, Walsh SR, Carroll N, Praseedom RK (2009) Radiation exposure during laparoscopic cholecystectomy with routine intraoperative cholangiography. Surg Endosc 23:1845–1848PubMedCrossRef Karthikesalingam A, Markar SR, Weerakkody R, Walsh SR, Carroll N, Praseedom RK (2009) Radiation exposure during laparoscopic cholecystectomy with routine intraoperative cholangiography. Surg Endosc 23:1845–1848PubMedCrossRef
25.
Zurück zum Zitat Flum DR, Flowers C, Veenstra DL (2003) A cost-effectiveness analysis of intraoperative cholangiography in the prevention of bile duct injury during laparoscopic cholecystectomy. J Am Coll Surg 196:385–393PubMedCrossRef Flum DR, Flowers C, Veenstra DL (2003) A cost-effectiveness analysis of intraoperative cholangiography in the prevention of bile duct injury during laparoscopic cholecystectomy. J Am Coll Surg 196:385–393PubMedCrossRef
26.
Zurück zum Zitat Schaafsma BE, Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL (2011) The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. J Surg Oncol 104(3):323–332PubMedCrossRef Schaafsma BE, Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL (2011) The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. J Surg Oncol 104(3):323–332PubMedCrossRef
27.
Zurück zum Zitat Aoki T, Murakami M, Yasuda D, Shimizu Y, Kusano T, Matsuda K, Niiya T, Kato H, Murai N, Otsuka K, Kusano M, Kato T (2010) Intraoperative fluorescent imaging using indocyanine green for liver mapping and cholangiography. J Hepatobiliary Pancreat Surg 17(5):590–594CrossRef Aoki T, Murakami M, Yasuda D, Shimizu Y, Kusano T, Matsuda K, Niiya T, Kato H, Murai N, Otsuka K, Kusano M, Kato T (2010) Intraoperative fluorescent imaging using indocyanine green for liver mapping and cholangiography. J Hepatobiliary Pancreat Surg 17(5):590–594CrossRef
28.
Zurück zum Zitat Ishizawa T, Bandai Y, Ijichi M, Kaneko J, Hasegawa K, Kokudo N (2010) Fluorescent cholangiography illuminating the biliary tree during laparoscopic cholecystectomy. Br J Surg 97(9):1369–1377PubMedCrossRef Ishizawa T, Bandai Y, Ijichi M, Kaneko J, Hasegawa K, Kokudo N (2010) Fluorescent cholangiography illuminating the biliary tree during laparoscopic cholecystectomy. Br J Surg 97(9):1369–1377PubMedCrossRef
29.
Zurück zum Zitat Garden OJ (2010) Fluorescent cholangiography illuminating the biliary tree during laparoscopic cholecystectomy (Br J Surg 2010; 97: 1369–1377). Br J Surg 9:1378CrossRef Garden OJ (2010) Fluorescent cholangiography illuminating the biliary tree during laparoscopic cholecystectomy (Br J Surg 2010; 97: 1369–1377). Br J Surg 9:1378CrossRef
30.
Zurück zum Zitat Ishizawa T, Kaneko J, Inoue Y, Takemura N, Seyama Y, Aoki T, Beck Y, Sugawara Y, Hasegawa K, Harada N, Ijichi M, Kusaka K, Shibasaki M, Bandai Y, Kokudo N (2011) Application of fluorescent cholangiography to single-incision laparoscopic cholecystectomy. Surg Endosc 25(8):2631–2636PubMedCrossRef Ishizawa T, Kaneko J, Inoue Y, Takemura N, Seyama Y, Aoki T, Beck Y, Sugawara Y, Hasegawa K, Harada N, Ijichi M, Kusaka K, Shibasaki M, Bandai Y, Kokudo N (2011) Application of fluorescent cholangiography to single-incision laparoscopic cholecystectomy. Surg Endosc 25(8):2631–2636PubMedCrossRef
31.
Zurück zum Zitat Spinoglio G, Lenti LM, Maglione V, Lucido FS, Priora F, Bianchi PP, Grosso F, Quarati R (2012) Single-site robotic cholecystectomy (SSRC) versus single-incision laparoscopic cholecystectomy (SILC): comparison of learning curves. First European experience. Surg Endosc 26(6):1648–1655PubMedCrossRef Spinoglio G, Lenti LM, Maglione V, Lucido FS, Priora F, Bianchi PP, Grosso F, Quarati R (2012) Single-site robotic cholecystectomy (SSRC) versus single-incision laparoscopic cholecystectomy (SILC): comparison of learning curves. First European experience. Surg Endosc 26(6):1648–1655PubMedCrossRef
32.
Zurück zum Zitat Wren SM, Curet MJ (2011) Single-port robotic cholecystectomy: results from a first human use clinical study of the new da Vinci single-site surgical platform. Arch Surg 146(10):1122–1127PubMedCrossRef Wren SM, Curet MJ (2011) Single-port robotic cholecystectomy: results from a first human use clinical study of the new da Vinci single-site surgical platform. Arch Surg 146(10):1122–1127PubMedCrossRef
33.
Zurück zum Zitat Kroh M, El-Hayek K, Rosenblatt S, Chand B, Escobar P, Kaouk J, Chalikonda S (2011) First human surgery with a novel single-port robotic system: cholecystectomy using the da Vinci Single-Site platform. Surg Endosc 25(11):3566–3573PubMedCrossRef Kroh M, El-Hayek K, Rosenblatt S, Chand B, Escobar P, Kaouk J, Chalikonda S (2011) First human surgery with a novel single-port robotic system: cholecystectomy using the da Vinci Single-Site platform. Surg Endosc 25(11):3566–3573PubMedCrossRef
34.
Zurück zum Zitat Morel P, Hagen ME, Bucher P, Buchs NC, Pugin F (2011) Robotic single-port cholecystectomy using a new platform: initial clinical experience. J Gastrointest Surg 15(12):2182–2186PubMedCrossRef Morel P, Hagen ME, Bucher P, Buchs NC, Pugin F (2011) Robotic single-port cholecystectomy using a new platform: initial clinical experience. J Gastrointest Surg 15(12):2182–2186PubMedCrossRef
35.
Zurück zum Zitat Pietrabissa A, Sbrana F, Morelli L, Badessi F, Pugliese L, Vinci A, Klersy C, Spinoglio G (2012) Overcoming the challenges of single-incision cholecystectomy with robotic single-site technology. Arch Surg 147(8):709–714PubMedCrossRef Pietrabissa A, Sbrana F, Morelli L, Badessi F, Pugliese L, Vinci A, Klersy C, Spinoglio G (2012) Overcoming the challenges of single-incision cholecystectomy with robotic single-site technology. Arch Surg 147(8):709–714PubMedCrossRef
36.
Zurück zum Zitat Buchs NC, Hagen ME, Pugin F, Volonte F, Bucher P, Shiffer E, Morel P (2012) Intra-operative fluorescent cholangiography using indocyanin green during robotic single site cholecystectomy. Int J Med Robot 8(4):436–440PubMedCrossRef Buchs NC, Hagen ME, Pugin F, Volonte F, Bucher P, Shiffer E, Morel P (2012) Intra-operative fluorescent cholangiography using indocyanin green during robotic single site cholecystectomy. Int J Med Robot 8(4):436–440PubMedCrossRef
37.
Zurück zum Zitat Houston JP, Thompson AB, Gurfinkel M, Sevick-Muraca EM (2003) Sensitivity and depth penetration of continuous wave versus frequency-domain photon migration near-infrared fluorescence contrast-enhanced imaging. Photochem Photobiol 77:420–430PubMedCrossRef Houston JP, Thompson AB, Gurfinkel M, Sevick-Muraca EM (2003) Sensitivity and depth penetration of continuous wave versus frequency-domain photon migration near-infrared fluorescence contrast-enhanced imaging. Photochem Photobiol 77:420–430PubMedCrossRef
Metadaten
Titel
Real-time near-infrared (NIR) fluorescent cholangiography in single-site robotic cholecystectomy (SSRC): a single-institutional prospective study
verfasst von
Giuseppe Spinoglio
Fabio Priora
Paolo Pietro Bianchi
Francesco Saverio Lucido
Alessio Licciardello
Valeria Maglione
Federica Grosso
Raul Quarati
Ferruccio Ravazzoni
Luca Matteo Lenti
Publikationsdatum
01.06.2013
Verlag
Springer-Verlag
Erschienen in
Surgical Endoscopy / Ausgabe 6/2013
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-012-2733-2

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