Erschienen in:
01.02.2009 | Case Report
Idiopathic orbital inflammatory disease successfully treated with rituximab
verfasst von:
Marcelo Derbli Schafranski
Erschienen in:
Clinical Rheumatology
|
Ausgabe 2/2009
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Abstract
We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.