nach oben

Journal of Behavioral Medicine

Erschienen in:

05.10.2017

Cancer-related loneliness mediates the relationships between social constraints and symptoms among cancer patients

verfasst von: Rebecca N. Adams, Catherine E. Mosher, Joseph G. Winger, Rafat Abonour, Kurt Kroenke

Erschienen in: Journal of Behavioral Medicine | Ausgabe 2/2018

Einloggen, um Zugang zu erhalten

Abstract

Cancer patients have high rates of persistent and disabling symptoms. Evidence suggests that social constraints (e.g., avoidance and criticism) negatively impact symptoms, but pathways linking these variables have yet to be identified. This study examined whether cancer-related loneliness (i.e., feeling socially disconnected related to having cancer) mediated the relationships between social constraints and symptoms (i.e., pain interference, fatigue, sleep disturbance, and cognitive complaints) in patients with various cancers (N = 182). Patients (51% female, mean age = 59) were recruited from the Indiana Cancer Registry and completed questionnaires assessing social constraints, cancer-related loneliness, and symptoms. Structural equation modeling was used to evaluate the hypothesized relationships among variables. The model demonstrated good fit. Consistent with our hypothesis, cancer-related loneliness mediated the relationships between social constraints and each symptom. Findings suggest that addressing cancer-related loneliness in symptom management interventions may mitigate the negative impact of social constraints on outcomes.

Adams, R. N., Mosher, C. E., Abonour, R., Robertson, M. J., Champion, V. L., & Kroenke, K. (2016a). Cognitive and situational precipitants of loneliness among patients with cancer: A qualitative analysis. Oncology Nursing Forum, 43, 156–163. doi:10.1188/16.ONF.156-163 CrossRefPubMedPubMedCentral

Adams, R. N., Mosher, C. E., Cohee, A. A., Stump, T. E., Monahan, P. O., Sledge, G. W., et al. (2016b). Avoidant coping and self-efficacy mediate relationships between perceived social constraints and symptoms among long-term breast cancer survivors. Psycho-Oncology. doi:10.1002/pon.4119

Adams, R. N., Mosher, C. E., Rand, K. L., Hirsh, A. T., Monahan, P. O., Abonour, R., et al. (2017). The Cancer Loneliness Scale and Cancer-Related Negative Social Expectations Scale: Development and validation. Quality of Life Research. doi:10.1007/s11136-017-1518-4

Agustsdottir, S., Kristinsdottir, A., Jonsdottir, K., Larusdottir, S. O., Smari, J., & Valdimarsdottir, H. B. (2010). The impact of dispositional emotional expressivity and social constraints on distress among prostate cancer patients in Iceland. British Journal of Health Psychology, 15, 51–61. doi:10.1348/135910709X426148 CrossRefPubMed

Amtmann, D., Cook, K. F., Jensen, M. P., Chen, W.-H., Choi, S., Revicki, D., et al. (2010). Development of a PROMIS item bank to measure pain interference. Pain, 150, 173–182. doi:10.1016/j.pain.2010.04.025 CrossRefPubMedPubMedCentral

Barsevick, A. M., Irwin, M. R., Hinds, P., Miller, A., Berger, A., Jacobsen, P., et al. (2013). Recommendations for high-priority research on cancer-related fatigue in children and adults. Journal of the National Cancer Institute, 105, 1432–1440. doi:10.1093/jnci/djt242 CrossRefPubMedPubMedCentral

Bower, J. E. (2014). Cancer-related fatigue—Mechanisms, risk factors, and treatments. Nature Reviews Clinical Oncology, 11, 597–609. doi:10.1038/nrclinonc.2014.127 CrossRefPubMedPubMedCentral

Buysse, D. J., Yu, L., Moul, D. E., Germain, A., Stover, A., Dodds, N. E., et al. (2010). Development and validation of patient-reported outcome measures for sleep disturbance and sleep-related impairments. Sleep, 33, 781. doi:10.1093/sleep/33.6.781 CrossRefPubMedPubMedCentral

Cacioppo, J. T., & Hawkley, L. C. (2009). Perceived social isolation and cognition. Trends in Cognitive Sciences, 13, 447–454. doi:10.1016/j.tics.2009.06.005 CrossRefPubMedPubMedCentral

Cella, D., Davis, K., Breitbart, W., & Curt, G. (2001). Cancer-related fatigue: Prevalence of proposed diagnostic criteria in a United States sample of cancer survivors. Journal of Clinical Oncology, 19, 3385–3391. doi:10.1200/JCO.2001.19.14.3385 CrossRefPubMed

Cella, D., Lai, J.-S., Nowinski, C., Victorson, D., Peterman, A., Miller, D., et al. (2012). Neuro-QOL brief measures of health-related quality of life for clinical research in neurology. Neurology, 78, 1860–1867. doi:10.1212/WNL.0b013e318258f744 CrossRefPubMedPubMedCentral

Cella, D., Riley, W., Stone, A., Rothrock, N., Reeve, B., Yount, S., et al. (2010). The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008. Journal of Clinical Epidemiology, 63, 1179–1194. doi:10.1016/j.jclinepi.2010.04.011 CrossRefPubMedPubMedCentral

Cella, D., Yount, S., Rothrock, N., Gershon, R., Cook, K., Reeve, B., et al. (2007). The Patient-Reported Outcomes Measurement Information System (PROMIS): Progress of an NIH roadmap cooperative group during its first two years. Medical Care, 45, S3–S11. doi:10.1097/01.mlr.0000258615.42478.55 CrossRefPubMedPubMedCentral

Cleary, E. H., & Stanton, A. L. (2015). Mediators of an internet-based psychosocial intervention for women with breast cancer. Health Psychology, 34, 477–485. doi:10.1037/hea0000170 CrossRefPubMed

Dagan, M., Sanderman, R., Hoff, C., Meijerink, W. J., Baas, P. C., van Haastert, M., et al. (2014). The interplay between partners’ responsiveness and patients’ need for emotional expression in couples coping with cancer. Journal of Behavioral Medicine, 37, 828–838. doi:10.1007/s10865-013-9543-4 CrossRefPubMed

Danhauer, S. C., Russell, G. B., Tedeschi, R. G., Jesse, M. T., Vishnevsky, T., Daley, K., et al. (2013). A longitudinal investigation of posttraumatic growth in adult patients undergoing treatment for acute leukemia. Journal of Clinical Psychology in Medical Settings, 20, 13–24. doi:10.1007/s10880-012-9304-5 CrossRefPubMedPubMedCentral

Eakin, E. G., & Strycker, L. A. (2001). Awareness and barriers to use of cancer support and information resources by HMO patients with breast, prostate, or colon cancer: Patient and provider perspectives. Psycho-Oncology, 10, 103–113. doi:10.1002/pon.500 CrossRefPubMed

Ferrell, B., Dow, K. H., & Grant, M. (1995). Measurement of the quality of life in cancer survivors. Quality of Life Research, 4, 523–531. doi:10.1007/BF00634747 CrossRefPubMed

Fitzpatrick, J., Liang, S., Feng, D., Crawford, D., Sorell, G. T., & Morgan-Fleming, B. (2006). Social values and self-disclosure: A comparison of Chinese native, Chinese resident (in US) and North American spouses. Journal of Comparative Family Studies, 37, 113–127.

Fukui, S., Koike, M., Ooba, A., & Uchitomi, Y. (2003). The effect of a psychosocial group intervention on loneliness and social support for Japanese women with primary breast cancer. Oncology Nursing Forum, 30, 823–830. doi:10.1188/03.ONF.823-830 CrossRefPubMed

Gatchel, R. J., Peng, Y. B., Peters, M. L., Fuchs, P. N., & Turk, D. C. (2007). The biopsychosocial approach to chronic pain: Scientific advances and future directions. Psychological Bulletin, 133, 581–624. doi:10.1037/0033-2909.133.4.581 CrossRefPubMed

Glare, P. A., Davies, P. S., Finlay, E., Gulati, A., Lemanne, D., Moryl, N., et al. (2014). Pain in cancer survivors. Journal of Clinical Oncology, 32, 1739–1747. doi:10.1200/JCO.2013.52.4629 CrossRefPubMedPubMedCentral

Halbert, C. H., Wrenn, G., Weathers, B., Delmoor, E., Ten Have, T., & Coyne, J. C. (2010). Sociocultural determinants of men’s reactions to prostate cancer diagnosis. Psycho-Oncology, 19, 553–560. doi:10.1002/pon.1574 CrossRefPubMedPubMedCentral

Harrington, C. B., Hansen, J. A., Moskowitz, M., Todd, B. L., & Feuerstein, M. (2010). It’s not over when it’s over: Long-term symptoms in cancer survivors—A systematic review. The International Journal of Psychiatry in Medicine, 40, 163–181. doi:10.2190/PM.40.2.c CrossRefPubMed

Hawkley, L. C., & Cacioppo, J. T. (2003). Loneliness and pathways to disease. Brain, Behavior, and Immunity, 17, 98–105. doi:10.1016/S0889-1591(02)00073-9 CrossRef

Howlader, N., Noone, A. M., Krapcho, M., Miller, D., Bishop, K., Kosary, C. L., et al. (Eds.). (2017). SEER cancer statistics review, 1975–2014, National Cancer Institute, Bethesda, MD, https://seer.cancer.gov/csr/1975_2014/, based on November 2016 SEER data submission, posted to the SEER web site, April 2017

Hoyt, M. A. (2009). Gender role conflict and emotional approach coping in men with cancer. Psychology and Health, 24, 981–996. doi:10.1080/08870440802311330 CrossRefPubMed

Hu, L., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling, 6, 1–55. doi:10.1080/10705519909540118 CrossRef

Janelsins, M. C., Kesler, S. R., Ahles, T. A., & Morrow, G. R. (2014). Prevalence, mechanisms, and management of cancer-related cognitive impairment. International Review of Psychiatry, 26, 102–113. doi:10.3109/09540261.2013.864260 CrossRefPubMedPubMedCentral

Jaremka, L. M., Andridge, R. R., Fagundes, C. P., Alfano, C. M., Povoski, S. P., Lipari, A. M., et al. (2014). Pain, depression, and fatigue: Loneliness as a longitudinal risk factor. Health Psychology, 33, 948–957. doi:10.1037/a0034012 CrossRefPubMed

Jaremka, L. M., Fagundes, C. P., Glaser, R., Bennett, J. M., Malarkey, W. B., & Kiecolt-Glaser, J. K. (2013). Loneliness predicts pain, depression, and fatigue: Understanding the role of immune dysregulation. Psychoneuroendocrinology, 38, 1310–1317. doi:10.1016/j.psyneuen.2012.11.016 CrossRefPubMed

Jensen, R. E., King-Kallimanis, B. L., Sexton, E., Reeve, B. B., Moinpour, C. M., Potosky, A. L., et al. (2016). Measurement properties of PROMIS Sleep Disturbance Short Forms in a large, ethnically diverse cancer cohort. Psychological Test and Assessment Modeling, 58, 353–370.

Kline, R. B. (2011). Principles and practice of structural equation modeling (3rd ed.). New York: The Guilford Press.

Kroenke, K., Johns, S. A., Theobald, D., Wu, J., & Tu, W. (2013). Somatic symptoms in cancer patients trajectory over 12 months and impact on functional status and disability. Supportive Care in Cancer, 21, 765–773. doi:10.1007/s00520-012-1578-5 CrossRefPubMed

Kroenke, K., Zhong, X., Theobald, D., Wu, J., Tu, W., & Carpenter, J. S. (2010). Somatic symptoms in patients with cancer experiencing pain or depression: Prevalence, disability, and health care use. Archives of Internal Medicine, 170, 1686–1694. doi:10.1001/archinternmed.2010.337 CrossRefPubMedPubMedCentral

Lai, J.-S., Cella, D., Choi, S., Junghaenel, D. U., Christodoulou, C., Gershon, R., et al. (2011). How item banks and their application can influence measurement practice in rehabilitation medicine: A PROMIS fatigue item bank example. Archives of Physical Medicine and Rehabilitation, 92, S20–S27. doi:10.1016/j.apmr.2010.08.033 CrossRefPubMedPubMedCentral

Lai, J.-S., Crane, P. K., & Cella, D. (2006). Factor analysis techniques for assessing sufficient unidimensionality of cancer related fatigue. Quality of Life Research, 15, 1179–1190. doi:10.1007/s11136-006-0060-6 CrossRefPubMed

Lepore, S. (2001). A social–cognitive processing model of emotional adjustment to cancer. In A. Baum & B. L. Andersen (Eds.), Psychosocial interventions for cancer (pp. 99–118). Washington, DC: American Psychological Association.CrossRef

Lepore, S., & Revenson, T. (2007). Social constraints on disclosure and adjustment to cancer. Social and Personality Psychology Compass, 1, 313–333. doi:10.1111/j.1751-9004.2007.00013.x CrossRef

Lepore, S., Silver, R. C., Wortman, C. B., & Wayment, H. A. (1996). Social constraints, intrusive thoughts, and depressive symptoms among bereaved mothers. Journal of Personality and Social Psychology, 70, 271–292. doi:10.1037//0022-3514.70.2.271 CrossRefPubMed

Magasi, S., Ryan, G., Revicki, D., Lenderking, W., Hays, R. D., Brod, M., et al. (2012). Content validity of patient-reported outcome measures: Perspectives from a PROMIS meeting. Quality of Life Research, 21, 739–746. doi:10.1007/s11136-009-9496-9 CrossRefPubMed

Mao, J. J., Armstrong, K., Bowman, M. A., Xie, S. X., Kadakia, R., & Farrar, J. T. (2007). Symptom burden among cancer survivors: Impact of age and comorbidity. The Journal of the American Board of Family Medicine, 20, 434–443. doi:10.3122/jabfm.2007.05.060225 CrossRefPubMed

Masi, C. M., Chen, H.-Y., Hawkley, L. C., & Cacioppo, J. T. (2010). A meta-analysis of interventions to reduce loneliness. Personality and Social Psychology Review, 15, 219–266. doi:10.1177/1088868310377394 CrossRefPubMed

Mosher, C. E., Lepore, S., Wu, L., Austin, J., Valdimarsdottir, H., Rowley, S., et al. (2012). Social correlates of distress following hematopoietic stem cell transplantation: Exploring the role of loneliness and cognitive processing. Journal of Health Psychology, 17, 1022–1032. doi:10.1177/1359105311432490 CrossRefPubMedPubMedCentral

Peplau, L. A., & Perlman, D. (1982). Perspectives on loneliness. In L. A. Peplau & D. Perlman (Eds.), Loneliness: A sourcebook of current theory, research and therapy (pp. 1–18). New York: Wiley.

Rijken, M., Komproe, I. H., Ros, W. J., Winnubst, J. A., & Heesch, N. C. (1995). Subjective well-being of elderly women: Conceptual differences between cancer patients, women suffering from chronic ailments and healthy women. British Journal of Clinical Psychology, 34, 289–300. doi:10.1111/j.2044-8260.1995.tb01463.x CrossRefPubMed

Samarel, N., Tulman, L., & Fawcett, J. (2002). Effects of two types of social support and education on adaptation to early-stage breast cancer. Research in Nursing & Health, 25, 459–470. doi:10.1002/nur.10061 CrossRef

Savard, J., & Morin, C. M. (2001). Insomnia in the context of cancer: A review of a neglected problem. Journal of Clinical Oncology, 19, 895–908. doi:10.1200/JCO.2001.19.3.895 CrossRefPubMed

Savard, J., Simard, S., Blanchet, J., Ivers, H., & Morin, C. M. (2001). Prevalence, clinical characteristics, and risk factors for insomnia in the context of breast cancer. Sleep, 24, 583. doi:10.1093/sleep/24.5.583 CrossRefPubMed

Schmidt, J. E., Beckjord, E., Bovbjerg, D. H., Low, C. A., Posluszny, D. M., Lowery, A. E., et al. (2016). Prevalence of perceived cognitive dysfunction in survivors of a wide range of cancers: Results from the 2010 LIVESTRONG survey. Journal of Cancer Survivorship, 10, 302–311. doi:10.1007/s11764-015-0476-5 CrossRefPubMed

Servaes, P., Verhagen, S., & Bleijenberg, G. (2002). Determinants of chronic fatigue in disease-free breast cancer patients: A cross-sectional study. Annals of Oncology, 13, 589–598. doi:10.1093/annonc/mdf082 CrossRefPubMed

Stachler, R. J., Schultz, L. R., Nerenz, D., & Yaremchuk, K. L. (2014). PROMIS evaluation for head and neck cancer patients: A comprehensive quality-of-life outcomes assessment tool. The Laryngoscope, 124, 1368–1376. doi:10.1002/lary.23853 CrossRefPubMed

Teresi, J. A., Ocepek-Welikson, K., Cook, K. F., Kleinman, M., Ramirez, M., Reid, M. C., et al. (2016). Measurement equivalence of the Patient Reported Outcomes Measurement Information System^®(PROMIS^®) Pain Interference Short Form items: Application to ethnically diverse cancer and palliative care populations. Psychological Test and Assessment Modeling, 58, 255–307.PubMedPubMedCentral

van den Beuken-van Everdingen, M., De Rijke, J., Kessels, A., Schouten, H., Van Kleef, M., & Patijn, J. (2007). Prevalence of pain in patients with cancer: A systematic review of the past 40 years. Annals of Oncology, 18, 1437–1449. doi:10.1093/annonc/mdm056 CrossRefPubMed

Von Ah, D., Carpenter, J. S., Saykin, A., Monahan, P., Wu, J., Yu, M., et al. (2012). Advanced cognitive training for breast cancer survivors: A randomized controlled trial. Breast Cancer Research and Treatment, 135, 799–809. doi:10.1007/s10549-012-2210-6 CrossRef

Wagner, L. I., Schink, J., Bass, M., Patel, S., Diaz, M. V., Rothrock, N., et al. (2015). Bringing PROMIS to practice: Brief and precise symptom screening in ambulatory cancer care. Cancer, 121, 927–934. doi:10.1002/cncr.29104 CrossRefPubMed

Wang, X. S., Zhao, F., Fisch, M. J., O’mara, A. M., Cella, D., Mendoza, T. R., et al. (2014). Prevalence and characteristics of moderate to severe fatigue: A multicenter study in cancer patients and survivors. Cancer, 120, 425–432. doi:10.1002/cncr.28434 CrossRefPubMedPubMedCentral

Widows, M. R., Jacobsen, P. B., & Fields, K. K. (2000). Relation of psychological vulnerability factors to posttraumatic stress disorder symptomatology in bone marrow transplant recipients. Psychosomatic Medicine, 62, 873–882. doi:10.1097/00006842-200011000-00018 CrossRefPubMed

Wilson, R. S., Krueger, K. R., Arnold, S. E., Schneider, J. A., Kelly, J. F., Barnes, L. L., et al. (2007). Loneliness and risk of Alzheimer disease. Archives of General Psychiatry, 64, 234–240. doi:10.1001/archpsyc.64.2.234 CrossRefPubMed

Wong, C. C. Y., & Lu, Q. (2016). Do social constraints always hurt? Acculturation moderates the relationships between social constraints and physical symptoms of Chinese American breast cancer survivors. Asian American Journal of Psychology, 7, 129–136. doi:10.1037/aap0000045 CrossRef

Yeung, N. C., Ramirez, J., & Lu, Q. (2017). Perceived stress as a mediator between social constraints and sleep quality among Chinese American breast cancer survivors. Supportive Care in Cancer. doi:10.1007/s00520-017-3632-9

Yu, L., Buysse, D. J., Germain, A., Moul, D. E., Stover, A., Dodds, N. E., et al. (2012). Development of short forms from the PROMIS™ sleep disturbance and sleep-related impairment item banks. Behavioral Sleep Medicine, 10, 6–24. doi:10.1080/15402002.2012.636266 CrossRef

Titel: Cancer-related loneliness mediates the relationships between social constraints and symptoms among cancer patients
verfasst von: Rebecca N. Adams
Catherine E. Mosher
Joseph G. Winger
Rafat Abonour
Kurt Kroenke
Publikationsdatum: 05.10.2017
Verlag: Springer US
Erschienen in: Journal of Behavioral Medicine / Ausgabe 2/2018
Print ISSN: 0160-7715
Elektronische ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-017-9892-5

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Cancer-related loneliness mediates the relationships between social constraints and symptoms among cancer patients

Abstract

Neu im Fachgebiet Psychiatrie

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

ADHS-Medikation erhöht das kardiovaskuläre Risiko

Klinikreform soll zehntausende Menschenleben retten

Typ-2-Diabetes und Depression folgen oft aufeinander

Update Psychiatrie

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2018

Psychological pathways from racial discrimination to cortisol in African American males and females

Relation of parent knowledge to glycemic control among emerging adults with type 1 diabetes: a mediational model

The longitudinal, bidirectional relationships between parent reports of child secondhand smoke exposure and child smoking trajectories

Developing a typology of patient-generated behavioral goals for cognitive behavioral therapy for chronic pain (CBT-CP): classification and predicting outcomes

Adaptation to inflammatory rheumatic disease: Do illness representations predict patients’ physical functioning over time? A complex relationship

Baseline predictors of DMT reinitiation among patients with multiple sclerosis following an MI–CBT intervention

Neu im Fachgebiet Psychiatrie

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

ADHS-Medikation erhöht das kardiovaskuläre Risiko

Klinikreform soll zehntausende Menschenleben retten

Typ-2-Diabetes und Depression folgen oft aufeinander

Update Psychiatrie