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Journal of Neuro-Oncology

Erschienen in:

01.07.2015 | Editors' Invited Manuscript

Combining immunotherapy with radiation for the treatment of glioblastoma

verfasst von: Kevin K. H. Chow, Wendy Hara, Michael Lim, Gordon Li

Erschienen in: Journal of Neuro-Oncology | Ausgabe 3/2015

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Abstract

Glioblastoma is a devastating cancer with universally poor outcomes in spite of current standard multimodal therapy. Immunotherapy is an attractive new treatment modality given its potential for exquisite specificity and its favorable side effect profile; however, clinical trials of immunotherapy in GBM have thus far shown modest benefit. Optimally combining radiation with immunotherapy may be the key to unlocking the potential of both therapies given the evidence that radiation can enhance anti-tumor immunity. Here we review this evidence and discuss considerations for combined therapy.

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Titel: Combining immunotherapy with radiation for the treatment of glioblastoma
verfasst von: Kevin K. H. Chow
Wendy Hara
Michael Lim
Gordon Li
Publikationsdatum: 01.07.2015
Verlag: Springer US
Erschienen in: Journal of Neuro-Oncology / Ausgabe 3/2015
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-015-1762-9

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