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Obesity Surgery
Erschienen in: Obesity Surgery 9/2022

19.07.2022 | Review

Impact of Opioid-Free Anesthesia on Analgesia and Recovery Following Bariatric Surgery: a Meta-Analysis of Randomized Controlled Studies

verfasst von: Kuo-Chuan Hung, Chong-Chi Chiu, Chih-Wei Hsu, Chien-Ming Lin, Shu-Wei Liao, I.-Chia Teng, I.-Wen Chen, Cheuk-Kwan Sun

Erschienen in: Obesity Surgery | Ausgabe 9/2022

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Abstract

This meta-analysis aimed at exploring the impact of opioid-free anesthesia (OFA) on pain score and opioid consumption in patients undergoing bariatric surgery (BS). Literature search identified eight eligible trials. Forest plot revealed a significantly lower pain score (mean difference (MD) =  − 0.96, p = 0.0002; 318 patients), but not morphine consumption (MD =  − 5.85 mg, p = 0.1; 318 patients) at postoperative 24 h in patients with OFA than in those without. Pooled analysis also showed a lower pain score (p = 0.002), morphine consumption (p = 0.0003) in the postanesthetic care unit, and risk of postoperative nausea/vomiting (p = 0.0003) in the OFA group compared to the controls. In conclusion, this meta-analysis demonstrated that opioid-free anesthesia improved pain outcomes immediately and at 24 h after surgery without a beneficial impact on opioid consumption at postoperative 24 h.

Key points

• Roles of opioid-free anesthesia (OFA) in bariatric surgery (BS) were investigated.
• Outcomes included postoperative pain score, opioid use, and nausea/vomiting risk.
• OFA was associated with lower 24-h pain score but not opioid consumption.
• Lower pain score and opioid consumption were noted in the postanesthetic care unit.
• OFA correlated with a lower risk of postoperative nausea/vomiting.
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Metadaten
Titel
Impact of Opioid-Free Anesthesia on Analgesia and Recovery Following Bariatric Surgery: a Meta-Analysis of Randomized Controlled Studies
verfasst von
Kuo-Chuan Hung
Chong-Chi Chiu
Chih-Wei Hsu
Chien-Ming Lin
Shu-Wei Liao
I.-Chia Teng
I.-Wen Chen
Cheuk-Kwan Sun
Publikationsdatum
19.07.2022
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 9/2022
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-022-06213-7

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