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Erschienen in: Current Urology Reports 6/2014

01.06.2014 | Minimally Invasive Surgery (V Bird and M Desai, Section Editors)

Early Experience of Robotic-Assisted Inguinal Lymphadenectomy: Review of Surgical Outcomes Relative to Alternative Approaches

verfasst von: Talar B. Kharadjian, Surena F. Matin, Curtis A. Pettaway

Erschienen in: Current Urology Reports | Ausgabe 6/2014

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Abstract

Inguinal lymph node dissection is a diagnostic and potentially curative treatment for penile carcinoma, which has historically been associated with high morbidity rates. This review summarizes the initial outcomes of robotic-assisted inguinal lymphadenectomy (RAIL) compared with the outcomes of the standard open and endoscopic approaches. The early experience suggests that RAIL may yield comparable oncologic outcomes, although future prospective studies of RAIL with greater numbers of participants and long-term follow-up are needed to evaluate the incidence and severity of perioperative and postoperative complications.
Literatur
2.
Zurück zum Zitat Gulia AK, Mandhani A, Muruganandham K, Kapoor R, Ansari MS, Srivastava A. Impact of delay in inguinal lymph node dissection in patients with carcinoma of penis. Indian J Cancer. 2009;46(3):214–8. doi:10.4103/0019-509X.51359.PubMedCrossRef Gulia AK, Mandhani A, Muruganandham K, Kapoor R, Ansari MS, Srivastava A. Impact of delay in inguinal lymph node dissection in patients with carcinoma of penis. Indian J Cancer. 2009;46(3):214–8. doi:10.​4103/​0019-509X.​51359.PubMedCrossRef
3.
Zurück zum Zitat Stuiver MM, Djajadiningrat RS, Graafland NM, Vincent AD, Lucas C, Horenblas S. Early wound complications after inguinal lymphadenectomy in penile cancer: a historical cohort study and risk-factor analysis. Eur Urol. 2013;64(3):486–92. doi:10.1016/j.eururo.2013.02.037. Epub 2013 Mar 6.PubMedCrossRef Stuiver MM, Djajadiningrat RS, Graafland NM, Vincent AD, Lucas C, Horenblas S. Early wound complications after inguinal lymphadenectomy in penile cancer: a historical cohort study and risk-factor analysis. Eur Urol. 2013;64(3):486–92. doi:10.​1016/​j.​eururo.​2013.​02.​037. Epub 2013 Mar 6.PubMedCrossRef
4.
Zurück zum Zitat D’Ancona CA, de Lucena RG, Querne FA, Martins MH, Denardi F, Netto Jr NR. Long-term followup of penile carcinoma treated with penectomy and bilateral modified inguinal lymphadenectomy. J Urol. 2004;172(2):498–501. discussion 501.PubMedCrossRef D’Ancona CA, de Lucena RG, Querne FA, Martins MH, Denardi F, Netto Jr NR. Long-term followup of penile carcinoma treated with penectomy and bilateral modified inguinal lymphadenectomy. J Urol. 2004;172(2):498–501. discussion 501.PubMedCrossRef
7.
Zurück zum Zitat Tobias-Machado M, Tavares A, Silva MN, Molina Jr WR, Forseto PH, Juliano RV, et al. Can video endoscopic inguinal lymphadenectomy achieve a lower morbidity than open lymph node dissection in penile cancer patients? J Endourol. 2008;22(8):1687–91. doi:10.1089/end.2007.0386.PubMedCrossRef Tobias-Machado M, Tavares A, Silva MN, Molina Jr WR, Forseto PH, Juliano RV, et al. Can video endoscopic inguinal lymphadenectomy achieve a lower morbidity than open lymph node dissection in penile cancer patients? J Endourol. 2008;22(8):1687–91. doi:10.​1089/​end.​2007.​0386.PubMedCrossRef
8.
Zurück zum Zitat Sotelo R, Sánchez-Salas R, Carmona O, Garcia A, Mariano M, Neiva G, et al. Endoscopic lymphadenectomy for penile carcinoma. J Endourol. 2007;21(4):364–7. discussion 367.PubMedCrossRef Sotelo R, Sánchez-Salas R, Carmona O, Garcia A, Mariano M, Neiva G, et al. Endoscopic lymphadenectomy for penile carcinoma. J Endourol. 2007;21(4):364–7. discussion 367.PubMedCrossRef
11.••
Zurück zum Zitat Matin SF, Cormier JN, Ward JF, Pisters LL, Wood CG, Dinney CP, et al. Phase 1 prospective evaluation of the oncological adequacy of robotic assisted video-endoscopic inguinal lymphadenectomy in patients with penile carcinoma. BJU Int. 2013;111(7):1068–74. doi:10.1111/j.1464-410X.2012.11729.x.This is the only prospective study of RAIL to date. In addition to reporting the operative findings of RAIL, the authors provide an independent surgeon's assessment of the procedure's oncologic adequacy.PubMedCentralPubMedCrossRef Matin SF, Cormier JN, Ward JF, Pisters LL, Wood CG, Dinney CP, et al. Phase 1 prospective evaluation of the oncological adequacy of robotic assisted video-endoscopic inguinal lymphadenectomy in patients with penile carcinoma. BJU Int. 2013;111(7):1068–74. doi:10.​1111/​j.​1464-410X.​2012.​11729.​x.This is the only prospective study of RAIL to date. In addition to reporting the operative findings of RAIL, the authors provide an independent surgeon's assessment of the procedure's oncologic adequacy.PubMedCentralPubMedCrossRef
12.
Zurück zum Zitat Thyavihally Y, Pednekar A, Pokharkar H. 850 da Vinci robot assisted VIDEO endoscopic inguinal lymphadenctomy (R-VEIL): initial exeperience. J Urol. 2013;189(4):349.CrossRef Thyavihally Y, Pednekar A, Pokharkar H. 850 da Vinci robot assisted VIDEO endoscopic inguinal lymphadenctomy (R-VEIL): initial exeperience. J Urol. 2013;189(4):349.CrossRef
13.•
Zurück zum Zitat Schwentner C, Todenhöfer T, Seibold J, Alloussi SH, Mischinger J, Aufderklamm S, et al. Endoscopic inguinofemoral lymphadenectomy–extended follow-up. J Endourol. 2013;27(4):497–503. doi:10.1089/end.2012.0489. Epub 2012 Dec 26. This retrospective study compares the differences in therapeutic outcome between endoscopic and open inguinofemoral lymphadenectomy over a mean follow-up period of 56 months for patients with penile carcinoma, melanoma, and other genitourinary malignancies. Statistical significance (calculated using chi squares and Fischer exact tests) between the two approaches was observed for operative time and complication rate.PubMedCrossRef Schwentner C, Todenhöfer T, Seibold J, Alloussi SH, Mischinger J, Aufderklamm S, et al. Endoscopic inguinofemoral lymphadenectomy–extended follow-up. J Endourol. 2013;27(4):497–503. doi:10.​1089/​end.​2012.​0489. Epub 2012 Dec 26. This retrospective study compares the differences in therapeutic outcome between endoscopic and open inguinofemoral lymphadenectomy over a mean follow-up period of 56 months for patients with penile carcinoma, melanoma, and other genitourinary malignancies. Statistical significance (calculated using chi squares and Fischer exact tests) between the two approaches was observed for operative time and complication rate.PubMedCrossRef
14.
Zurück zum Zitat Leijte JA, Hughes B, Graafland NM, Kroon BK, Olmos RA, Nieweg OE, et al. Two-center evaluation of dynamic sentinel node biopsy for squamous cell carcinoma of the penis. J Clin Oncol. 2009;27(20):3325–9. doi:10.1200/JCO.2008.20.6870. Epub 2009 May 4.PubMedCrossRef Leijte JA, Hughes B, Graafland NM, Kroon BK, Olmos RA, Nieweg OE, et al. Two-center evaluation of dynamic sentinel node biopsy for squamous cell carcinoma of the penis. J Clin Oncol. 2009;27(20):3325–9. doi:10.​1200/​JCO.​2008.​20.​6870. Epub 2009 May 4.PubMedCrossRef
15.••
Zurück zum Zitat Lam W, Alnajjar HM, La-Touche S, Perry M, Sharma D, Corbishley C, et al. Dynamic sentinel lymph node biopsy in patients with invasive squamous cell carcinoma of the penis: a prospective study of the long-term outcome of 500 inguinal basins assessed at a single institution. Eur Urol. 2013;63(4):657–63. doi:10.1016/j.eururo.2012.10.035. Epub 2012 Oct 27. This prospective study analyzed the use of DSNB and ultrasound scan both with and without fine-needle aspiration cytology for clinically node-negative squamous cell penile carcinoma. DSNB sensitivity was observed to be 92%, with a false-negative rate of 5% per inguinal basin. DSNB morbidity was found to be 7.6% in this series.PubMedCrossRef Lam W, Alnajjar HM, La-Touche S, Perry M, Sharma D, Corbishley C, et al. Dynamic sentinel lymph node biopsy in patients with invasive squamous cell carcinoma of the penis: a prospective study of the long-term outcome of 500 inguinal basins assessed at a single institution. Eur Urol. 2013;63(4):657–63. doi:10.​1016/​j.​eururo.​2012.​10.​035. Epub 2012 Oct 27. This prospective study analyzed the use of DSNB and ultrasound scan both with and without fine-needle aspiration cytology for clinically node-negative squamous cell penile carcinoma. DSNB sensitivity was observed to be 92%, with a false-negative rate of 5% per inguinal basin. DSNB morbidity was found to be 7.6% in this series.PubMedCrossRef
17.
Zurück zum Zitat El-Tabey NA, Shoma AM. Port site metastases after robot-assisted laparoscopic radical cystectomy. Urology. 2005;66(5):1110.PubMedCrossRef El-Tabey NA, Shoma AM. Port site metastases after robot-assisted laparoscopic radical cystectomy. Urology. 2005;66(5):1110.PubMedCrossRef
18.
Zurück zum Zitat Canter DJ, Dobbs RW, Jafri SM, Herrel LA, Ogan K, Delman KA, et al. Functional, oncologic, and technical outcomes after endoscopic groin dissection for penile carcinoma. Can J Urol. 2012;19(4):6395–400.PubMed Canter DJ, Dobbs RW, Jafri SM, Herrel LA, Ogan K, Delman KA, et al. Functional, oncologic, and technical outcomes after endoscopic groin dissection for penile carcinoma. Can J Urol. 2012;19(4):6395–400.PubMed
19.
Zurück zum Zitat Pahwa HS, Misra S, Kumar A, Kumar V, Agarwal A, Srivastava R. Video Endoscopic Inguinal Lymphadenectomy (VEIL)–a prospective critical perioperative assessment of feasibility and morbidity with points of technique in penile carcinoma. World J Surg Oncol. 2013;11:42. doi:10.1186/1477-7819-11-42.PubMedCentralPubMedCrossRef Pahwa HS, Misra S, Kumar A, Kumar V, Agarwal A, Srivastava R. Video Endoscopic Inguinal Lymphadenectomy (VEIL)–a prospective critical perioperative assessment of feasibility and morbidity with points of technique in penile carcinoma. World J Surg Oncol. 2013;11:42. doi:10.​1186/​1477-7819-11-42.PubMedCentralPubMedCrossRef
20.
Zurück zum Zitat Zhou XL, Zhang JF, Zhang JF, Zhou SJ, Yuan XQ. Endoscopic inguinal lymphadenectomy for penile carcinoma and genital malignancy: a preliminary report. J Endourol. 2013;27(5):657–61. doi:10.1089/end.2012.0437. Epub 2013 Mar 7.PubMedCrossRef Zhou XL, Zhang JF, Zhang JF, Zhou SJ, Yuan XQ. Endoscopic inguinal lymphadenectomy for penile carcinoma and genital malignancy: a preliminary report. J Endourol. 2013;27(5):657–61. doi:10.​1089/​end.​2012.​0437. Epub 2013 Mar 7.PubMedCrossRef
21.
Zurück zum Zitat Koifman L, Hampl D, Koifman N, Vides AJ, Ornellas AA. Radical open inguinal lymphadenectomy for penile carcinoma: surgical technique, early complications, and late utcomes– evaluation of 340 procedures. J Urol. 2013;190(6):2086–92. doi:10.1016/j.juro.2013.06.016. Epub 2013 Jun 11.PubMedCrossRef Koifman L, Hampl D, Koifman N, Vides AJ, Ornellas AA. Radical open inguinal lymphadenectomy for penile carcinoma: surgical technique, early complications, and late utcomes– evaluation of 340 procedures. J Urol. 2013;190(6):2086–92. doi:10.​1016/​j.​juro.​2013.​06.​016. Epub 2013 Jun 11.PubMedCrossRef
Metadaten
Titel
Early Experience of Robotic-Assisted Inguinal Lymphadenectomy: Review of Surgical Outcomes Relative to Alternative Approaches
verfasst von
Talar B. Kharadjian
Surena F. Matin
Curtis A. Pettaway
Publikationsdatum
01.06.2014
Verlag
Springer US
Erschienen in
Current Urology Reports / Ausgabe 6/2014
Print ISSN: 1527-2737
Elektronische ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-014-0412-7

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