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Journal of Gastrointestinal Cancer

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01.03.2013 | Review Article

Clinical and Endoscopic Features of Angiosarcoma of the Colon: Two Case Reports and a Review of the Literature

verfasst von: Muhammed Sherid, Humberto Sifuentes, Jeff Brasky, Dhiren A. Shah, Eli D. Ehrenpreis

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 1/2013

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Abstract

Background

Angiosarcoma of the gastrointestinal tract is an extremely rare tumor. We present two cases of angiosarcoma of the colon. One patient developed syncope and anemia and the other had rectal bleeding.

Discussion

Endoscopic findings of the colon were different; the first case demonstrated a reddened colonic fold without an obvious mass and the other had an ulcerated friable mass. Both of the tumors had positive immunohistochemical stains for CD31 and CD34 (one was also positive for CD117). Surgery was not performed in either case. Treatment included chemotherapy with imatinib for the first patient and paclitaxel for the second. Prognosis for this tumor is generally poor; in our cases, one patient was still alive after 5 months of follow-up and the other died within 2 months of diagnosis. After presenting our cases, we reviewed the current literature on angiosarcoma of the colon.

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Titel: Clinical and Endoscopic Features of Angiosarcoma of the Colon: Two Case Reports and a Review of the Literature
verfasst von: Muhammed Sherid
Humberto Sifuentes
Jeff Brasky
Dhiren A. Shah
Eli D. Ehrenpreis
Publikationsdatum: 01.03.2013
Verlag: Springer US
Erschienen in: Journal of Gastrointestinal Cancer / Ausgabe 1/2013
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-012-9431-0

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